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138 Possible Causes for Palpable Purpura, Raynaud's Disease

  • Vasculitis

    Some of the most common types of vasculitis are: Raynaud’s disease (Raynaud's phenomenon) Buerger’s disease (thromboangitis obliterans) Takayasu’s arteritis The UC Davis Vascular[] Cutaneous leukocytoclastic vasculitis (LCV) is type of small vessel vasculitis that commonly presents as palpable purpura involving the lower extremities and buttocks.[] Leukocytoclastic vasculitis (LCV) is a disease characterized by inflammation of small vessels presenting with petechiae and palpable purpura.[]

  • Polyarteritis Nodosa

    Skin: About 40% of patients develop a rash, bruising, nodules and Raynaud phenomenon . Cardiovascular system: Cardiac disease affects 35% of patients with PAN.[] Feels like there is an outbreak of vasculitis recently at the SFVA with a few morning reports on palpable purpura and it’s characteristic finding on pathology: leukocytoclastic[] Other systemic manifestations include cutaneous involvement (eg, subcutaneous nodules), purpura or Raynaud phenomenon, coronary arteritis, pericarditis, and hematologic abnormalities[]

  • Idiopathic Cryoglobulinemia

    phenomenon, Raynaud's phenomenon, retinal hemorrhage, secondary cryoglobulinemia, Sjögren syndrome, Sjögren's syndrome, simple cryoglobulinemia, SLE, stroke, systemic lupus[] Cryoglobulin deposition causes a vasculitis that leads to petechiae and palpable purpura.[] phenomenon Arterial thrombosis Gangrene Arthralgia and arthritis in the PIP and MCP joints (fingers, hands and toe joints), knees and ankles Fatigue Myalgias (muscle pains[]

  • Cryoimmunoglobulinemic Syndrome

    ’s disease — Bull.[] […] findings  Biopsy ... 1/2011 MMI RPGN.ppt presentation ... • RF high • palpable purpura (leukocytoclastic vasculitis ) • Dx: biopsy • Bx: basement membrane ...[] C0034091 HENOCH SCHONLEIN SYNDROME C0034152 THROMBOTIC THROMBOCYTOPENIC PURPURA C0034155 RAYNAUDS DISEASE C0034734 Raynauds Phenomenon C0034735 REITERS DISEASE C0035012 RENAL[]

  • Mixed Connective Tissue Disease

    Raynaud’s phenomenon is a common feature of this disease in which the fingers may become cold and numb during stress or in cold conditions.[] purpura Erythematous plaques reminiscent of discoid lupus erythematosus Facial erythema Hair loss ( localised scarring and diffuse non-scarring alopecia ) Painful dermal[] MCTD can be associated with Raynaud disease and can also cause arthritis, fevers and malaise (unexplainable fatigue).[]

  • Cryoglobulinemia

    Tabs Content Clinical Overview Diagnosis Indications for Testing Clinical signs and symptoms of cryoglobulinemia (eg, skin ulcers, digital pain, Raynaud disease) Laboratory[] Cutaneous lesions may include palpable purpura, urticaria-like lesions, livedo reticularis, Raynaud's phenomenon, acrocyanosis, gangrene and ulceration.[] Keys to Diagnosis: Palpable purpura in a dependent distribution is most suggestive of cryoglobulinemia.[]

  • Systemic Lupus Erythematosus

    […] is most common cause of mortality hip osteonecrosis is common in patients taking glucocorticoids Raynaud's phenomenon Presentation Symptoms fever pain in multiple joints[] purpura or urticarial vasculitis Livedo reticularis (a network pattern of blood vessels ) in 20–30% patients with SLE Papular mucinosis (deposits of mucin in skin) Calcinosis[] Anti-Ro/SSA antibodies have been associated with photosensitivity, a rash known as subacute cutaneous lupus, cutaneous vasculitis (palpable purpura), interstitial lung disease[]

  • Immune Complex Disease

    Questions and Answers about Raynaud's Phenomenon. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) [On-line information].[] A man with ocular myasthenia gravis had rapidly progressing pulmonary hemorrhage, acute renal failure, arthralgias, and palpable purpura.[] The clinical symptom is palpable purpura with predilection for the lower legs.[]

  • Hypocomplementemic Vasculitis

    It is also possible for one to additionally develop pulmonary or kidney disease, inflammation of the uvea and Raynaud phenomenon.[] There was scleral erythema, urticaria on the torso, palpable purpura on the legs, and swelling and tenderness of the hand joints. A diagnostic procedure was performed.[] Physical exam Palpable purpura is pathognomonic for vasculitis. Palpable purpura consists of elevated, nonblanching erythematous lesions.[]

  • Dermatomyositis

    Antisynthetase syndrome : myositis, arthritis, interstitial lung disease, mechanic's hands and Raynaud phenomenon Who gets dermatomyositis?[] purpura papules, ulcers, infarct, and possible digital gangrene caused by small- and medium-vessel vasculitis (inflammation of the blood vessels) Dystrophic cuticles Facial[] Associated conditions include: Raynaud's phenomenon. Other connective tissue diseases. Cardiovascular disease. Lung disease. 15. DIAGNOSTIC CRITERIA 1.[]

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