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27 Possible Causes for Pancytopenia, Polyclonal Hyperglobulinemia, Weakness

  • Multicentric Castleman's Disease

    Diffuse lymph-node enlargement, splenomegaly and pancytopenia were detected. Induction with Rituximab was made because pancytopenia was present.[ncbi.nlm.nih.gov] A physical exam showed tachypnea, generalized cutaneous hyperpigmentation and skin hardening of extremities, muscle weakness, hypoesthesia and hyporeflexia.[ncbi.nlm.nih.gov] hyperglobulinemia, elevated transaminases and renal disease. 2 , 5 , 7 Dispenzieri et al. 8 analyzed the clinical spectrum of Castleman’s disease in 113 patients.[pagepress.org]

  • Primary Myelofibrosis

    This is then followed by pancytopenia (a reduction in the number of red and white blood cells, as well as platelets).[aoporphan.com] CASE REPORT A 51-year-old Korean man was admitted to our hospital with general weakness and left-side abdominal pain.[ncbi.nlm.nih.gov] Polyclonal hyperglobulinemia may be present. Patients with sporadic idiopathic or familial pulmonary hypertension have significant marrow fibrosis.[patient-help.com]

  • HIV Infection

    […] osteomalacia* Protease inhibitors with statins: myopathy Hematologic or oncologic Anemia of chronic disease Lymphoma, multiple myeloma Bone marrow infiltration (leading to pancytopenia[aafp.org] A 35 year-old homosexual man presented with a 5-week history of headaches followed by a 3-week history of horizontal diplopia, limb weakness and right 6th cranial nerve palsy[ncbi.nlm.nih.gov] Hyperactivation is reflected in dramatic polyclonal hyperglobulinemia, only a portion of which is directed against HIV antigens;(59) bone marrow plasmacytosis;(60) heightened[hivinsite.ucsf.edu]

  • Castleman Disease

    There is often significant anemia which may be hemolytic, often reflecting pancytopenia or hemophagocytic syndrome (Stebbing 2009).[hivbook.com] Symptoms and signs of MCD include fever, night sweats, loss of appetite, nausea/vomiting, weight loss, cough, shortness of breath, weakness or fatigue from anemia, enlarged[secure.ssa.gov] The disease is characterized by fever, weight loss, anemia, polyclonal hyperglobulinemia, splenomegaly, thrombocytosis and peripheral lymphadenopathy.[ncbi.nlm.nih.gov]

  • Congenital Intrinsic Factor Deficiency

    Gene GIF (AR) Diagnostic Test Plasma Vitamin B12, Folate Neurological Ataxia, dystonia Non-Neurological Megaloblastic anemia, pancytopenia Treatment HydroxyCobalamin Level[treatable-id.org] Weakness: Asthenia in general, mental as well as physical; marked more so by the absence of any underlying infection.[symptoma.com] NOS (R77.1) monoclonal gammopathy (of undetermined significance) (D47.2) Excludes2: transplant failure and rejection (T86.-) D89.0 Polyclonal hypergammaglobulinemia Benign[en.wikisource.org]

  • Posthemorrhagic Anaemia of the Newborn

    […] with malformations 284.1 Pancytopenia Excludes: pancytopenia (due to) (with): aplastic anemia NOS (284.9) bone marrow infiltration (284.2) constitutional red blood cell aplasia[theodora.com] If the condition is severe the infants have weakness, tachycardia and distress out of proportion to any degree of cyanosis.[pediatrics.aappublications.org] NOS (R77.1) monoclonal gammopathy (of undetermined significance) (D47.2) Excludes2: transplant failure and rejection (T86.-) D89.0 Polyclonal hypergammaglobulinemia Benign[en.wikisource.org]

  • Idiopathic Cryoglobulinemia

    . • However, a high rate of hematologic side effects (mainly grade 3 and 4 pancytopenia) was recorded. 1. Saadoun D, et al.[slideshare.net] Legs Arms Weakness may be severe in rare patient Autonomic: Usually normal Electrophysiology: Axonal loss Treatment: Poor response Toxic (due to chemotherapy) Thalidomide[neuromuscular.wustl.edu] NOS ( R77.1 ) monoclonal gammopathy (of undetermined significance) ( D47.2 ) Excludes2 transplant failure and rejection ( T86 .-) D89.0 Polyclonal hypergammaglobulinemia[icd10coded.com]

  • Chronic Active Hepatitis

    Abstract A 28-year-old man was admitted to our department with intermittent fever, hepatosplenomegaly and pancytopenia.[ncbi.nlm.nih.gov] We report the case of a 53-year-old female patient, who developed bilateral blepharoptosis, limb weakness, dysphagia, and dyspnea several days after human natural interferon-beta[ncbi.nlm.nih.gov] hyperglobulinemia.[hepatitiscentral.com]

  • H Syndrome

    IVIC Syndrome with mild thrombocytopenia and leukocytosis; 4) WT Syndrome involving a wide array of hematologic abnormalities including easy bruising, hypoplastic anemia, pancytopenia[bloodjournal.org] The person will have weakness in their arms and legs. There may be weakness in muscles controlled by cranial nerves.[emedicinehealth.com] The facial weakness caused by Ramsay Hunt syndrome may make it difficult for you to close your eyelid.[mayoclinic.org]

  • Chronic Active Hepatitis B

    A 28-year-old man was admitted to our department with intermittent fever, hepatosplenomegaly and pancytopenia.[ncbi.nlm.nih.gov] Eventually, the liver damage can lead to symptoms such as weakness, loss of appetite, nausea, vomiting, itchy skin, jaundice, pain in the right upper abdomen, and fluid build[news-medical.net] hyperglobulinemia.[hepatitiscentral.com]

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