Create issue ticket

3,008 Possible Causes for Pancytopenia, Short Stature in Children, Wide Space Between the First and Second Toe

  • Down Syndrome

    Since the circulating blast count is often low in ML-DS and the predominant haematological picture may be of slowly progressive pancytopenia, a bone marrow aspirate is usually[doi.org] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] Short stature as the major manifestation of celiac disease in older children. Clin Pediatr 1986; 25:13–6. 12. Rossi TM, Kumar V, Lerner A, et al.[journals.lww.com]

  • Seckel Syndrome

    The 12-yr-old female had pancytopenia, which is seen occasionally in patients with Seckel syndrome and is also a feature of Fanconi anemia, a well-recognized autosomal recessive[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] One child had classical Seckel syndrome, a sib pair had the features of the syndrome with less severe short stature, and in two children the diagnosis was not confirmed.[ncbi.nlm.nih.gov]

  • Dubowitz Syndrome

    Neoplastic risk haematological malignancies and pancytopenia in 10%, childhood myelodysplasia in particular; lymphomas Inborn conditions appears to be normal or near to normal[atlasgeneticsoncology.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] More about psychosocial adaptation to short stature can be learned from parents of short children and from your growth clinic doctor, nurse and psychologist.[web.archive.org]

  • Shwachman Syndrome

    A suppressor mechanism could not be demonstrated as the cause of the severe pancytopenia, based on in vitro bone marrow co-culture experiments.[ncbi.nlm.nih.gov] Many children with this disease are short in stature and speech delays and slow development of motor skills are also common.[seattlecca.org] Lipomatosis of the pancreas found on MR and CT and the clinical findings pancytopenia, short stature, and recurrent infections are typical for Shwachman syndrome.[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Niemann-Pick Disease

    Patients with type B NPD have minimal neurologic involvement but pancytopenia is common.[symptoma.com] stature and eye abnormalities Type C Symptoms of the type C form of Niemann-Pick disease usually begin to appear in children around 5 years old.[healthline.com] Pancytopenia is common.[msdmanuals.com]

    Missing: Wide Space Between the First and Second Toe
  • Isovaleric Acidemia

    Severe pancytopenia developed in two infants with isovaleric acidemia.[ncbi.nlm.nih.gov] A case of isovaleric acidemia appearing as diabetic ketoacidosis with acute encephalopathy and pancytopenia was reported.[ncbi.nlm.nih.gov] She presented with two episodes of vomiting, poor activity and pancytopenia without obvious metabolic acidosis and hyperammonemia.[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Growth Failure

    Amenorrhea was initially attributed to low body weight ( Mild pancytopenia was first noted at age 16.[journals.aace.com] […] lead to short stature.[rileychildrens.org] LIG4 mutations were subsequently reported in individuals with microcephaly, mild immunodeficiency, developmental delay, and pancytopenia [O'Driscoll et al., 2001, 2004 ; Unal[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Aplastic Anemia

    Differentiation of AN-associated pancytopenia from other types of pancytopenia, especially idiopathic aplastic anemia (IAA), has not been studied.[ncbi.nlm.nih.gov] For example, children with Fanconi anemia may have abnormalities of the upper extremities, characteristic facies, short stature, and cafe-au-lait lesions.[clinicaladvisor.com] In children and young adults, short stature, café au lait spots and skeletal anomalies suggest the possibility of a congenital form of aplastic anaemia [ 5 ].[patient.info]

    Missing: Wide Space Between the First and Second Toe
  • Leukoerythroblastic Anemia

    Myeloproliferative Disease, Autosomal Recessive Myeloproliferative Disorder, Chronic, with Eosinophilia myeloproliferative neoplasm neonatal anemia normocytic anemia pancytopenia[rgd.mcw.edu] Congenital anomalies include short stature; microcephaly; hypogenitalism; strabismus; anomalies of the thumbs, radii, and kidneys and urinary tract; mental retardation; and[answers.com] Pancytopenia secondary to oxalosis in a 23-year-old woman. Blood 1998;91:4394. [ PUBMED ] [ FULLTEXT ] 4. Halil O, Farringdon K.[ijpmonline.org]

    Missing: Wide Space Between the First and Second Toe
  • Atelosteogenesis Type 2

    […] vision, see Arts syndrome ataxia-deafness-optic atrophy, lethal, see Arts syndrome ataxia-hypogonadism-choroidal dystrophy syndrome, see Boucher-Neuhäuser syndrome ataxia-pancytopenia[mygenomics.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] A constitutional short stature in children is not considered as a short stature or dwarfism as the condition happens temporarily and the child will resume normal growth eventually[epainassist.com]

Similar symptoms