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1,208 Possible Causes for Pancytopenia, Splenomegaly

  • Infectious Mononucleosis

    Clinical estimates of splenomegaly are fallible.[] […] infection as an adult is a risk factor for the development of multiple sclerosis. [1, 2] Hematologic complications can include development of autoimmune hemolytic anemia, pancytopenia[] In adolescent and adult patients presenting with sore throat, the presence of posterior cervical, inguinal or axillary adenopathy, palatine petechiae, splenomegaly, or atypical[]

  • Hairy Cell Leukemia

    Most patients are middle-aged to elderly adults and present with splenomegaly and pancytopenia.[] We should keep in mind other reasons for vasculitis such as lymphoproliferative disease, especially whose who have hematological abnormalities such as pancytopenia. 2014 Asia[] Abstract Hairy cell leukemia typically presents with pancytopenia and often mimics aplastic anemia.[]

  • Hypersplenism

    RESULTS: While 38 patients displayed splenomegaly, 121 showed normal spleen volumes at 6 months after LDLT (LDLT).[] Pancytopenia can be limited by reducing the volume of the functional spleen.[] He was initially asymptomatic though there was mild pancytopenia.[]

  • Visceral Leishmaniasis

    Infantile VL may begin suddenly, with high fever and vomiting, or insidiously, with irregular daily fever, anorexia, and marked splenomegaly.[] We present an unusual case of febrile pancytopenia in a nonagenarian who was diagnosed with visceral leishmaniasis.[] It can be difficult to diagnose this disease in endemic settings as several causes of febrile splenomegaly exist, notably malaria.[]

  • Leukoerythroblastic Anemia

    The French authors, Emil-Weil and Clerc, 1 in 1902, and Vaquez and Aubertin, 2 in 1904, first discussed a syndrome characterized by splenomegaly due to myeloid change and[] Myeloproliferative Disease, Autosomal Recessive Myeloproliferative Disorder, Chronic, with Eosinophilia myeloproliferative neoplasm neonatal anemia normocytic anemia pancytopenia[] Pancytopenia secondary to oxalosis in a 23-year-old woman. Blood 1998;91:4394. [ PUBMED ] [ FULLTEXT ] 4. Halil O, Farringdon K.[]

  • Primary Myelofibrosis

    Abstract We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[] This is then followed by pancytopenia (a reduction in the number of red and white blood cells, as well as platelets).[] Significant thrombopenia ( KEYWORDS: Myelofibrosis; Palliation; Splenic irradiation; Splenomegaly[]

  • Myeloproliferative Disease

    CML: demonstrates increased production of neutrophils and marked splenomegaly.[] Four years later, at the age of 16, her brother was diagnosed as having acute myelofibrosis, and some months afterwards he died from fulminant pneumonia coincidently with pancytopenia[] ( D61.82 ) pancytopenia (due to) (with) congenital (pure) red cell aplasia ( D61.01 ) pancytopenia (due to) (with) hairy cell leukemia ( C91.4- ) pancytopenia (due to) (with[]

  • Aggressive Systemic Mastocytosis

    Abstract A 43 year-old woman presented with fever, abdominal pain, epato-splenomegaly, ascites, cholestasis, anemia, thrombocytopenia and previous diagnosis of sclerosing[] […] organomegaly and organ dysfunction, impairment of hematopoietic function (which may result in disruption of the blood count ranging from isolated cytopenia to more or less marked pancytopenia[] Retro-orbital injections of P815 NT cells in syngeneic DBA/2 mice resulted in rapid development of aggressive SM within 13-16 days characterized by splenomegaly, extramedullary[]

  • Post-Polycythemia Vera Myelofibrosis

    KEYWORDS: myelofibrosis; ruxolitinib; splenomegaly; tumor lysis syndrome[] Later he developed leukopenia and pancytopenia. Bone marrow biopsies showed fibrosis.[] Enlargement of the spleen is called splenomegaly , which also contributes to causing pancytopenia, particularly thrombocytopenia and anemia .[]

  • Malignant Histiocytosis

    The long duration of massive splenomegaly suggests that this patient could represent a chronic form of MH.[] […] pancreas at initial presentation is exceptional, this entity should be included in the differential diagnosis of acute pancreatitis, especially when hepatosplenomegaly and pancytopenia[] Her clinical course was complicated in the last year by several infectious and noninfectious events, and after pancytopenia, fever, and extremely high levels of lactate dehydrogenase[]

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