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1,208 Possible Causes for Pancytopenia, Splenomegaly

  • Infectious Mononucleosis

    Clinical estimates of splenomegaly are fallible.[ncbi.nlm.nih.gov] […] infection as an adult is a risk factor for the development of multiple sclerosis. [1, 2] Hematologic complications can include development of autoimmune hemolytic anemia, pancytopenia[emedicine.com] In adolescent and adult patients presenting with sore throat, the presence of posterior cervical, inguinal or axillary adenopathy, palatine petechiae, splenomegaly, or atypical[ncbi.nlm.nih.gov]

  • Hairy Cell Leukemia

    Most patients are middle-aged to elderly adults and present with splenomegaly and pancytopenia.[icd9data.com] We should keep in mind other reasons for vasculitis such as lymphoproliferative disease, especially whose who have hematological abnormalities such as pancytopenia. 2014 Asia[ncbi.nlm.nih.gov] Abstract Hairy cell leukemia typically presents with pancytopenia and often mimics aplastic anemia.[ncbi.nlm.nih.gov]

  • Hypersplenism

    RESULTS: While 38 patients displayed splenomegaly, 121 showed normal spleen volumes at 6 months after LDLT (LDLT).[ncbi.nlm.nih.gov] Pancytopenia can be limited by reducing the volume of the functional spleen.[ncbi.nlm.nih.gov] He was initially asymptomatic though there was mild pancytopenia.[ncbi.nlm.nih.gov]

  • Visceral Leishmaniasis

    Infantile VL may begin suddenly, with high fever and vomiting, or insidiously, with irregular daily fever, anorexia, and marked splenomegaly.[ncbi.nlm.nih.gov] We present an unusual case of febrile pancytopenia in a nonagenarian who was diagnosed with visceral leishmaniasis.[ncbi.nlm.nih.gov] It can be difficult to diagnose this disease in endemic settings as several causes of febrile splenomegaly exist, notably malaria.[doi.org]

  • Leukoerythroblastic Anemia

    The French authors, Emil-Weil and Clerc, 1 in 1902, and Vaquez and Aubertin, 2 in 1904, first discussed a syndrome characterized by splenomegaly due to myeloid change and[jamanetwork.com] Myeloproliferative Disease, Autosomal Recessive Myeloproliferative Disorder, Chronic, with Eosinophilia myeloproliferative neoplasm neonatal anemia normocytic anemia pancytopenia[rgd.mcw.edu] Pancytopenia secondary to oxalosis in a 23-year-old woman. Blood 1998;91:4394. [ PUBMED ] [ FULLTEXT ] 4. Halil O, Farringdon K.[ijpmonline.org]

  • Primary Myelofibrosis

    Abstract We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[ncbi.nlm.nih.gov] This is then followed by pancytopenia (a reduction in the number of red and white blood cells, as well as platelets).[aoporphan.com] Significant thrombopenia ( KEYWORDS: Myelofibrosis; Palliation; Splenic irradiation; Splenomegaly[ncbi.nlm.nih.gov]

  • Myeloproliferative Disease

    CML: demonstrates increased production of neutrophils and marked splenomegaly.[ncbi.nlm.nih.gov] Four years later, at the age of 16, her brother was diagnosed as having acute myelofibrosis, and some months afterwards he died from fulminant pneumonia coincidently with pancytopenia[ncbi.nlm.nih.gov] ( D61.82 ) pancytopenia (due to) (with) congenital (pure) red cell aplasia ( D61.01 ) pancytopenia (due to) (with) hairy cell leukemia ( C91.4- ) pancytopenia (due to) (with[icd10data.com]

  • Aggressive Systemic Mastocytosis

    Abstract A 43 year-old woman presented with fever, abdominal pain, epato-splenomegaly, ascites, cholestasis, anemia, thrombocytopenia and previous diagnosis of sclerosing[ncbi.nlm.nih.gov] […] organomegaly and organ dysfunction, impairment of hematopoietic function (which may result in disruption of the blood count ranging from isolated cytopenia to more or less marked pancytopenia[orpha.net] Retro-orbital injections of P815 NT cells in syngeneic DBA/2 mice resulted in rapid development of aggressive SM within 13-16 days characterized by splenomegaly, extramedullary[ncbi.nlm.nih.gov]

  • Post-Polycythemia Vera Myelofibrosis

    KEYWORDS: myelofibrosis; ruxolitinib; splenomegaly; tumor lysis syndrome[ncbi.nlm.nih.gov] Later he developed leukopenia and pancytopenia. Bone marrow biopsies showed fibrosis.[duo.uio.no] Enlargement of the spleen is called splenomegaly , which also contributes to causing pancytopenia, particularly thrombocytopenia and anemia .[en.wikipedia.org]

  • Malignant Histiocytosis

    The long duration of massive splenomegaly suggests that this patient could represent a chronic form of MH.[ncbi.nlm.nih.gov] […] pancreas at initial presentation is exceptional, this entity should be included in the differential diagnosis of acute pancreatitis, especially when hepatosplenomegaly and pancytopenia[ncbi.nlm.nih.gov] Her clinical course was complicated in the last year by several infectious and noninfectious events, and after pancytopenia, fever, and extremely high levels of lactate dehydrogenase[ncbi.nlm.nih.gov]

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