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15 Possible Causes for Pansystolic Murmur, Systolic Thrill at Lower Left Sternal Border

  • Ventricular Septal Defect

    3 to 4/6 holosystolic murmur (with or without thrill) at the lower left sternal border; this murmur is usually audible within the first few days of life (see table Heart[msdmanuals.com] Small lesions with minimal shunting may be asymptomatic, however may have a loud harsh pansystolic murmur heard on precordial ausculation over the left sternal border 10 .[radiopaedia.org] Muscular defects can be heard along the lower left sternal border and may vary in intensity as the defect size changes with muscular contraction throughout systole.[circ.ahajournals.org]

  • Tricuspid Valve Insufficiency

    In severe TR, a right jugular venous thrill may be palpable, as may systolic hepatic pulsation and an RV impulse at the left lower sternal border.[merckmanuals.com] Common findings include distended jugular veins, hepatomegaly, pansystolic murmur auscultated in the parasternal area at the 4th intercostal space.[symptoma.com] Cardiac murmurs are often present: A pansystolic murmur, which may signify blood flow through the ventricular septal defect.[patient.info]

  • Large Ventricular Septal Defect

    3 to 4/6 holosystolic murmur (with or without thrill) at the lower left sternal border; this murmur is usually audible within the first few days of life (see table Heart[merckmanuals.com] Ventricular septal defect-functional types Small-Medium Left Right Shunts w/o Pulmonary HTN Acyanotic, asymptomatic, grade II-IV/VI pansystolic murmur Management May resolve[medical-dictionary.thefreedictionary.com] Classically, a VSD causes a pathognomonic holo- or pansystolic murmur. Auscultation is generally considered sufficient for detecting a significant VSD.[en.wikipedia.org]

  • Acyanotic Congenital Heart Disease

    Physical Signs Systolic thrill at the lower and middle left sternal border Loud single S2 Loud systolic ejection murmur at the lower left sternal border With increasing right[rcemlearning.co.uk] murmur LLSE ECG: normal (smaller VSD) or LVH RVH (larger VSD) 8 VSD’s Larger defect: MDM @ apex (mitral flow murmur) narrowly split S2 and loud P2 S3 CXR: cardiomegaly increased[slideplayer.com] Auscultatory findings Harsh h olosystolic murmur over the left lower sternal border ; typically louder in small defects Mid- diastolic murmur over cardiac apex Systolic thrill[amboss.com]

  • Apical Myocardial Infarction

    This murmur is loudest along the lower left sternal border and is associated with a palpable parasternal systolic thrill. RV and LV S3 gallops are common.[emedicine.medscape.com] Examination revealed distress with an apical pansystolic murmur.[ceemjournal.org] Present with a new systolic ejection murmur heard best at the left upper sternal border, with radiation to the neck and a new pansystolic murmur at the apex, with radiation[patient.info]

  • Tetralogy of Fallot

    Systolic thrill at the lower left sternal border. Aortic ejection click.[patient.info] A pansystolic murmur is usually heard, and the second heart sound is faint or absent.[medical-dictionary.thefreedictionary.com] Cardiac auscultation, revealed a grade IV/VI pansystolic murmur at the left sternal border.[omicsonline.org]

  • Congenital Absence of Ductus Arteriosus

    Physical Signs Systolic thrill at the lower and middle left sternal border Loud single S2 Loud systolic ejection murmur at the lower left sternal border With increasing right[rcemlearning.co.uk] Pertinent clinical findings included presence of central cyanosis and a loud pansystolic murmur on right side of lower sternum. Chest X-ray showed cardiomegaly.[omicsonline.org] Auscultatory findings Harsh h olosystolic murmur over the left lower sternal border ; typically louder in small defects Mid- diastolic murmur over cardiac apex Systolic thrill[amboss.com]

  • Right Ventricular Hypertrophy

    3 to 4/6 holosystolic murmur (with or without thrill) at the lower left sternal border; this murmur is usually audible within the first few days of life (see table Heart[merckmanuals.com] Signs: raised jugular venous pulse (JVP), left parasternal lift, an accentuated second pulmonary sound, right ventricular gallop, usually a pansystolic murmur over the tricuspid[escardio.org] Small VSDs typically produce murmurs ranging from a grade 1 to 2/6 high-pitched, short systolic murmur (due to tiny defects that actually close during late systole) to a grade[merckmanuals.com]

  • Septic Embolus

    A systolic thrill was palpable at the lower left sternal border. Localized crackles were audible at the base of the right lung.[comprped.com] On cardiac examination, a grade 4/6 harsh pansystolic murmur at the lower left sternal border and a loud second heart sound were detected.[comprped.com] On cardiac examination, a grade 4/6 harsh pansystolic murmur at the lower left sternal border and a loud second heart sound were detected.[comprped.com]

  • Anomalies of Great Veins, Congenital

    On examination, there is a systolic murmur at the lower left sternal border (LLSB), and a systolic thrill may be present if there is a large shunt.[ahcmedia.com] A pansystolic murmur of tricuspid insufficiency or an ejection murmur of PS may be heard.[hawaii.edu]

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