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112 Possible Causes for Paracrystalline Inclusions

  • Hereditary Myopathy with Lactic Acidosis due to ISCU Deficiency

    (d) Electron microscopy showing abnormal collection of mitochondria with paracrystalline inclusions (arrowhead), osmiophilic inclusions (large arrowhead) and mitochondrial[en.wikipedia.org]

  • Carotid Body Paraganglioma

    inclusions Sustentacular cells wrap around chief cells and lack neurosecretory granules No desmosomes Board review question #1 Capsular invasion Cytologic atypia Increased[pathologyoutlines.com] […] risk for catecholamine crisis and hemorrhage Electron microscopy description Chief cells have abundant cytoplasmic neurosecretory granules May have giant mitochondria with paracrystalline[pathologyoutlines.com]

  • Hypervitaminosis E

    The theoretical pathogenesis of muscle damage and the possible origin of paracrystalline inclusion bodies are discussed.[link.springer.com] Bardosi A & Dickmann U (1987) Necrotizing myopathy with paracrystalline inclusion bodies in hypervitaminosis E. Acta Neuropathologica 75 (2), 166-172 PubMed .[vetstream.com] Summary A necrotizing, nonprogressive myopathy with unusual paracrystalline inclusion bodies is described in a patient who underwent long-term treatment with megadoses of[link.springer.com]

  • Cerebrotendinous Xanthomatosis

    inclusions and increased number of peroxisomes [ Federico et al 1989 ].[ctxinfo.org] Histologic liver findings include electron-dense amorphous material surrounded by smooth endoplasmic reticulum [ Salen et al 1978 ] and abnormalities in mitochondria with paracrystalline[ctxinfo.org]

  • Zidovudine

    inclusions.[link.springer.com] […] individuals had signs of moderate to severe mitochondrial abnormalities shown by both light microscopy and EM, characterized by severe destruction, vacuolization, and rare paracrystalline[link.springer.com]

  • Myopathy

    Paracrystalline inclusions were present in three patients (DNAJB6). The most frequent mutation in was in DES, followed by ZASP.[ncbi.nlm.nih.gov] Histiochemistry shows, destructive mitochondrial myopathy with "ragged-red" fibers seen on trichrome stain, indicative of abnormal mitochondria with paracrystalline inclusions[hiv.imedpub.com] Ultrastructural findings showed significant differences in intranuclear rods, Z-disc thickness, and intranuclear inclusions between gene mutation subgroups.[ncbi.nlm.nih.gov]

  • Oculopharyngeal Muscular Dystrophy

    inclusions.[ncbi.nlm.nih.gov] In the present presumably recessively inherited case, with a clinical history of oculopharyngeal myopathy and distal weakness, paracrystalline mitochondrial inclusions and[ncbi.nlm.nih.gov] Muscle biopsy showed only minor light microscopic abnormalities but electron microscopy revealed fibres containing paracrystalline mitochondrial inclusions.[ncbi.nlm.nih.gov]

  • Syphilitic Gumma of the Testis

    The present study revealed five types of paracrystalline inclusion in contrast to the one or two types described in previous reports.[onlinelibrary.wiley.com] All five types of paracrystalline inclusions were found in relatively normal as well as azoospermic (estrogen-treated) testes. Get access to the full text of this article[onlinelibrary.wiley.com] inclusions in the cytoplasm of Leydig cells.[onlinelibrary.wiley.com]

  • Propionic Acidemia

    The liver contained fatty vacuoles, enlarged mitochondria with paracrystalline inclusions, and numerous peroxisomes whereas the skeletal muscle also had lipid vacuoles and[ncbi.nlm.nih.gov]

  • Infantile Neuroaxonal Dystrophy

    Lying within the Schwann cell cytoplasm is an abnormal mitochondrion (arrow) showing loss of cristae and also containing a fine paracrystalline inclusion.[brain.oxfordjournals.org] inclusion within Schwann cell cytoplasm and also in axons ( Fig. 1 ).[brain.oxfordjournals.org] […] fibroblast culture and standard transmission electron microscopy showed cutaneous nerves containing grossly enlarged and pleomorphic mitochondria with altered cristae and a rare paracrystalline[brain.oxfordjournals.org]

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