[…] disease characterized by discrete, focal, punctate keratoderma on the palms and soles and/or slowly progressive spastic paralysis, predominantly affecting the lower limbs
[orpha.net]
predominantly affecting the lower limbs.
[ncbi.nlm.nih.gov]
Homepage Rare diseases Search Search for a rare disease Palmoplantar keratoderma-spastic paralysis syndrome Disease definition A rare, genetic punctate palmoplantar keratoderma
[orpha.net]