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211 Possible Causes for Paroxysmal Cold Hemoglobinuria

  • Autoimmune Hemolytic Anemia

    Classifications of AIHA include warm AIHA, cold agglutinin syndrome, paroxysmal cold hemoglobinuria, mixed-type AIHA, and drug-induced AIHA.[ncbi.nlm.nih.gov] (CAS), and paroxysmal cold hemoglobinuria (PCH) are entirely complement-dependent disorders.[ncbi.nlm.nih.gov] It can be idiopathic or secondary, and classified as warm, cold (cold hemagglutinin disease (CAD) and paroxysmal cold hemoglobinuria) or mixed, according to the thermal range[ncbi.nlm.nih.gov]

  • Hemolytic Anemia

    Corticosteroids Sometimes splenectomy For paroxysmal cold hemoglobinuria, avoiding the cold Sometimes immunosuppressants The best treatment for paroxysmal cold hemoglobinuria[merckmanuals.com] Primary AIHA includes warm reactive, cold reactive and paroxysmal cold hemoglobinuria.[pedclerk.bsd.uchicago.edu] […] in patients with paroxysmal cold hemoglobinuria and with drug-immune hemolytic anemia mediated by the ternary complex mechanism.”[errolozdalga.com]

  • Syphilis

    There is no proven alternative to penicillin for treatment of maternal syphilis. We report 2 case-patients with maternal syphilis who were successfully treated without penicillin. We used amoxicillin and probenecid for the first case-patient and amoxicillin, probenecid, and ceftriaxone for the second case-patient.[ncbi.nlm.nih.gov]

  • Postviral Syndrome

    Abstract Eighty-nine of 150 patients having a Monospot test filled out a questionnaire about their illness, and the General Health Questionnaire. They completed a follow-up questionnaire 6 months later. Twelve (8%) had a positive Monospot. Twenty-eight of 83 serum samples tested (34%) were positive for VP1[…][ncbi.nlm.nih.gov]

  • Acquired Hemolytic Anemia

    […] antibody autoimmune hemolytic anemia Idiopathic cold hemagglutinin syndrome Infectious mononucleosis and mycoplasma (atypical) pneumonia Paroxysmal cold hemoglobinuria (rare[en.wikipedia.org] Paroxysmal cold hemoglobinuria. Ulcerative colitis. 47.[slideshare.net] […] hemolytic anemia Warm antibody autoimmune hemolytic anemia Idiopathic Systemic lupus erythematosus (SLE) Evans' syndrome (antiplatelet antibodies and hemolytic antibodies) Cold[en.wikipedia.org]

  • Paroxysmal Cold Hemoglobinuria

    Paroxysmal cold hemoglobinuria (PCH) has been a recognized medical entity for more than 150 years.[symptoma.com] Successful perioperative management is described, as is a discussion of paroxysmal cold hemoglobinuria.[ncbi.nlm.nih.gov] Episodic hemolysis in paroxysmal cold hemoglobinuria is usually associated with a biphasic (Donath-Landsteiner) IgG cold-reactive complement-fixing autohemolysin with anti-P[ncbi.nlm.nih.gov]

  • Immune Hemolytic Anemia

    In paroxysmal cold hemoglobinuria, constitutional symptoms are prominent during a paroxysm.[karger.com] Paroxysmal cold hemoglobinuria (Donath-Landsteiner syndrome) is a rare type of cold antibody hemolytic anemia.[merckmanuals.com] […] autoimmune hemolytic anemia, which includes cold agglutinin disease and paroxysmal cold hemoglobinuria.[en.wikipedia.org]

  • Cold Agglutinin Disease

    cold hemoglobinuria Paroxysmal nocturnal hemoglobinuria Thalassemias Connective tissue disease Antiphospholipid syndrome Background Epidemiology Incidence – Age – most common[arupconsult.com] AIHA can be classified as warm autoimmune hemolytic anemia or cold autoimmune hemolytic anemia, which includes cold agglutinin disease and paroxysmal cold hemoglobinuria.[en.wikipedia.org] Rare syndromes include IgG antibodies that cause direct intravascular hemolysis, such as paroxysmal cold hemoglobinuria.[doi.org]

  • Congenital Syphilis

    cold hemoglobinuria TABLE 4 Management of infants born to women with reactive treponemal tests (TTs) during pregnancy* Scenario Baseline and monthly assessment for signs[cps.ca] cold hemoglobinuria Hutchinson’s triad Interstitial keratitis Hutchinson’s teeth Sensorineural hearing loss DIAGNOSTIC TESTING The surveillance case definition for congenital[ncbi.nlm.nih.gov] […] giving it the appearance of a berry Eighth nerve deafness (sensory neural deafness) Age: 10-40 years *Rarer features are meningitis, chorioretinitis, nephritic syndrome and paroxysmal[cps.ca]

  • Drug-Induced Autoimmune Hemolytic Anemia

    […] anemia Type 1 Excludes Evans syndrome ( D69.41 ) hemolytic disease of newborn ( P55.- ) paroxysmal cold hemoglobinuria ( D59.6 ) drug-induced D59.0 hemolytic (newborn) P55.9[icd10data.com] Paroxysmal cold hemoglobinuria D59.8 Other acquired hemolytic anemias D59.9 Acquired hemolytic anemia, unspecified Inclusion term(s): Idiopathic hemolytic anemia, chronic[icd10coded.com] Contrary to cold autoimmune hemolytic anemia (e.g., cold agglutinin disease and paroxysmal cold hemoglobinuria) which happens in cold temperature (28–31 C), WAIHA happens[en.wikipedia.org]

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