Create issue ticket

298 Possible Causes for Pathological Fracture, Skin Discoloration

  • Kaposi Sarcoma

    skin lesion on both legs, initially considered as chronic vein insufficiency.[ncbi.nlm.nih.gov] […] female of Greek ethnicity, with no history of HIV infection or immunosuppression, presented to the Surgical Out-patient Department of our Center, with complaints of extensive discolored[ncbi.nlm.nih.gov]

  • Infectious Mononucleosis

    CT is best utilized for skull fracture and intracranial bleeding, whereas MRI may be ordered for prolonged symptoms, worsening symptoms or other suspected structural pathology[choosingwisely.org] Skin discoloration and icterus is sometime seen in patients with hepatosplenomegaly, and is slightly more common in elderly individuals.[symptoma.com] skin.[hopkinsmedicine.org]

  • Diabetic Gangrene

    fracture, joint dislocation and fragmentation of articular cartilage Diabetic neuropathy is the most common cause.[slideshare.net] Bullae and the bluish skin discoloration are classic findings of gas gangrene and were noted have begun to show at the time of presentation of this case (Figures 1 and 2 )[intjem.springeropen.com] Gas gangrene is marked by a high fever, brownish pus *, gas bubbles under the skin, skin discoloration, and a foul odor.[humanillnesses.com]

  • Gaucher Disease

    fractures, and pyogenic osteomyelitis.[ncbi.nlm.nih.gov] […] of the skin due to diminished oxygen), and low blood pressure.[cerezyme.com] BMD was low in 11 patients (50%); neither BMD nor HSA were associated with pathological fractures.[ncbi.nlm.nih.gov]

  • Maffucci Syndrome

    Pathological fractures can arise in affected metaphyses and diaphyses of the long bones and are common (26%).[en.wikipedia.org] Figure 1: Multiple bluish and hyperpigmented nodules on (a) dorsal aspect and (b) ulnar aspect of the right forearm and hand, (c) note the violaceous discoloration underneath[ijdvl.com] These tumors commonly lead to pathological fractures of bones, and although most of the tumors are benign, there is a 15-20% incidence of malignancy.[stanfordhealthcare.org]

  • Multiple Myeloma

    Bottom Line: Among patients with myeloma, bisphosphonates were associated with lower rates of pathological fractures and skeletal-related events compared with placebo or no[ncbi.nlm.nih.gov] Symptoms associated with thrombocytopenia include abnormal bleeding episodes that often result in purplish discoloration of the skin resulting from bleeding (hemorrhaging)[rarediseases.org] fracture.[ncbi.nlm.nih.gov]

  • Secondary Hyperparathyroidism

    PHPT must always be evaluated in patients with clinical histories of nephrolithiasis, nephrocalcinosis, osseous pain, subperiosteal resorption, and pathologic fractures, as[reumatologiaclinica.org] Signs and symptoms of chronic kidney disease may be seen in patients who have the condition, which includes bruising and skin discoloration, pruritus, pericardial rub, edema[symptoma.com] Clinical features are due to: Excessive calcium resorption from bone: Osteopenia and osteoporosis, presenting as bone pain and pathological fractures.[patient.info]

  • Thalassemia

    Erythroid hyperplasia can result in typical structural bone abnormalities with marrow hyperplasia, bone thinning, maxillary hyperplasia, and pathologic fractures.[emedicine.medscape.com] Signs and symptoms vary but may include mild to severe anemia, paleness, fatigue, yellow discoloration of skin ( jaundice ), and bone problems. [2] Beta thalassemia is caused[rarediseases.info.nih.gov] Pathologic fractures, especially in long bones and vertebrae, can result.[emedicine.medscape.com]

  • Osteogenesis Imperfecta

    These cases present with several pathologic fractures in the body during autopsies.[symptoma.com] […] teeth Curved spine, called scoliosis Feeling very tired Skin that is easily hurt Hearing loss that starts in early adulthood Can’t stand warm temperatures Loose joints Short[webmd.com] Malabsorption syndromes: celiac disease, pancreatitis, Malignancy (lymphoma,leukemia, multiple myeloma). pathologic fractures, osteolytic bone lesions, hematologic and immune[clinicaladvisor.com]

  • Metastatic Adenocarcinoma of the Breast

    Local examination showed skin discoloration and 2 x2 cm lump in left upper outer quadrant. There was no discharge per nipple or enlarged lymph nodes.[ispub.com]

Further symptoms

Similar symptoms