Create issue ticket

336 Possible Causes for perchlorate

  • Influenza

    […] influenza virions (A/California/07/2009 (H1N1), A/Hong Kong/4801/2014 (H3N2) and B/Brisbane/60/2008) labelled with 1,1'-dioctadecyl-3,3,3',3'-tetramethylindodicarbocyanine perchlorate[ncbi.nlm.nih.gov]

  • Pendred's Syndrome

    The other 6 had a slight drop in the perchlorate discharge test results with normal hearing.[ncbi.nlm.nih.gov] Thyroid function tests were normal, and the perchlorate discharge test was negative.[ncbi.nlm.nih.gov] The investigations included scintigram, perchlorate discharge test and audiometery. The perchlorate discharge was positive in index case.[ncbi.nlm.nih.gov]

  • Iodine-induced Hypothyroidism

    Abstract We studied the effect of potassium perchlorate (KClO4) in patients with hypothyroidism due to amiodarone.[ncbi.nlm.nih.gov] Iodide perchlorate discharge tests were carried out before SSKI administration, and TRH tests were performed on the last day of iodide administration.[ncbi.nlm.nih.gov] We have studied 11 euthyroid women with a previous history of PPT to determine the incidence of subtle defects in thyroid function measured by iodide-perchlorate (I-ClO4)[ncbi.nlm.nih.gov]

  • Congenital Goiter

    Iodine kinetic analysis after the ingestion of potassium perchlorate and methimazole was compatible with a leak of nonhormonal iodide from the thyroid.[ncbi.nlm.nih.gov] Perchlorate tests were negative. Serum T3 and T4 were decreased, TSH was increased and Tg was within the lower limit of normal.[ncbi.nlm.nih.gov] PIOD is diagnosed with 50-90% release after perchlorate administration (and can be confirmed by genetic testing).[orpha.net]

  • Iodide Peroxidase Deficiency

    Defects in TPO cause a severe form of congenital hypothyroidism characterized by a complete and immediate release of accumulated radioiodide from the thyroid after sodium perchlorate[ncbi.nlm.nih.gov] Fifty per cent of the thyroidal iodine was released by perchlorate, indicating a partial iodide organification defect.[nejm.org] PIOD is diagnosed with 50-90% release after perchlorate administration (and can be confirmed by genetic testing).[orpha.net]

  • Corrosive Chemical

    Perchloric acid. Perchloric acid is an extremely corrosive chemical and strong oxidizing agent that requires special precautions.[www2.bakersfieldcollege.edu] Perchloric acid is an extremely powerful oxidizer and must be kept away from all organic materials. It should also be stored seperately.[ehs.princeton.edu] Perchloric acid presents special hazards.[blink.ucsd.edu]

  • Familial Thyroid Dyshormonogenesis 6

    PIOD is diagnosed with 50-90% release after perchlorate administration (and can be confirmed by genetic testing).[orpha.net] This can be measured by determining the amount of radioiodine lost from the gland after the administration of potassium perchlorate (Perchlorate discharge test); the percentage[indianpediatrics.net] TIOD diagnosis is based on high radioactive iodine (RAI) uptake of the thyroid gland followed by more than 90% release after sodium perchlorate administration.[orpha.net]

  • Drinking Water

    Read frequently asked questions about perchlorate in drinking water Perchlorate Peer Reviews As part of EPA’s commitment to ensuring the safety of America’s drinking water[epa.gov] […] health effects of perchlorate exposure and mode of action for perchlorate toxicity (NRC, 2005).[federalregister.gov] Perchlorate EPA received several comments on perchlorate in response to the draft CCL 3.[federalregister.gov]

  • Antithyroid Agent

    A less common antithyroid agent is potassium perchlorate.[en.wikipedia.org] Perchloric acid is made by treating NaClO4 with HCl, NaClO4 finds only minimal use in pyrotechnics because it is hygroscopic, ammonium and potassium perchlorates are preferred[wikivisually.com] Its heat of formation is 382.75 kJ mol 1, sodium perchlorate is the precursor to many other perchlorate salts, often taking advantage of their low solubility relative to NaClO4[wikivisually.com]

  • Familial Thyroid Dyshormonogenesis Type 1

    This can be measured by determining the amount of radioiodine lost from the gland after the administration of potassium perchlorate (Perchlorate discharge test); the percentage[indianpediatrics.net] PIOD is diagnosed with 50-90% release after perchlorate administration (and can be confirmed by genetic testing).[orpha.net] Potassium perchlorate is usually given 2 hours after the administration of radioiodine.[indianpediatrics.net]

Further symptoms