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37 Possible Causes for Perifollicular Fibrosis

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  • Kimura Disease

    Hematoxylin-eosin staining showed follicular hyperplasia with perifollicular fibrosis, an eosinophil infiltrate, and proliferation of capillary vessels.[]

  • X-Linked Keratosis Follicularis Spinulosa Decalvans

    The dermis revealed perifollicular lymphocytic infiltrate with eccentric epithelial atrophy, polytrichia, and perifollicular fibrosis [Figure 4] .[] A punch biopsy specimen from the scalp showed follicular plugging in the epidermis with mild acanthosis, early perifollicular fibrosis with mild lymphocytic infiltrate.[] fibrosis 0030054 Photophobia Extreme sensitivity of the eyes to light Light hypersensitivity [ more ] 0000613 Scarring alopecia of scalp 0004552 Sparse and thin eyebrow Thin[]

  • Tinea Capitis

    There was widespread scarring and fibrosis.[] Histological examination showed hair plugging, and a dense perifollicular infiltrate of plasma cells, lymphocytes, and neutrophils.[]

  • Telogen Effluvium

    […] inflammation and fibrosis.[] Specimens were sectioned horizontally and vertically and were examined for terminal and velluslike (miniaturized) hairs, follicular stelae, follicular units, and perifollicular[] Significant degrees of inflammation and fibrosis were present in only 10% to 12% of cases of CTE and normal controls, but occurred in 37% of cases of AGA.[]

  • Frontal Fibrosing Alopecia

    However, scalp biopsy specimens from the frontal hair margin showed perifollicular fibrosis and lymphocytic inflammation.[] Scalp biopsy of the affected frontal hairline revealed peribulbar lymphocytic inflammation, but no evidence of lichenoid inflammation, perifollicular fibrosis or scarring.[] Histological examination showed perifollicular fibrosis and lymphocytic inflammation around the isthmus and infundibular areas of the follicles.[]

  • Scurvy

    Although unnecessary for diagnosis, histological findings demonstrate perifollicular inflammation and hemorrhage, fibrosis, and hyperkeratosis, amongst dilated hair follicles[]

  • Finasteride

    Perifollicular fibrosis: Pathogenetic role in androgenetic alopecia Biological and Pharmaceutical Bullentin 29(6), (2006) .[]

  • Drug Eruptions

    Pink/fleshy perifollicular papules with diffuse alopecia. Horizontal section shows perifollicular fibrosis consistent with scarring alopecia.[] Nephrogenic systemic fibrosis has been associated with gadolinium contrast agents used for MRI studies.[]

  • Atrophodermia Vermiculata

    The histopathological findings of these lesions predominantly showed lymphocytic perifolliculitis with perifollicular fibrosis. The epidermis was normal.[] The histopathological findings showed mild perifollicular and perivascular inflammation, perifollicular fibrosis and decrease in number and atrophy of the hair follicles.[]

  • Hypothyroidism

    Thyroid gland histology demonstrated perifollicular or interlobular fibrosis without inflammation in all three cases, including a euthyroid case.[] Characteristic fibrosis in the thyroid gland was observed even in a euthyroid case.[]

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