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102 Possible Causes for Perineal Ulceration

  • Perineal Fistula

    Surgery treatment for perineal fistula entails removing the ulcerated tissue and the anal sacs to enhance healing of the anal and perineal regions.[] Metronidazole therapy for perineal Crohn's disease: a follow-up study . Gastroenterology 83 , 383–387 (1982). 56. Solomon, M. J. et al .[] WHAT ARE PERINEAL OR ANAL FISTULAS?[]

  • Lymphogranuloma Venereum

    The infection is usually transmitted by sexual contact, and the presenting lesions are generally located in the genital and perineal region.[] For unexplained reasons, inflammation of the perineal lymph nodes develops in women and may lead to scarring and ulceration of the labia, rectal mucosa, and vagina.[] […] area  Painless infiltrated nodules that soon slough.  A shallow, sharply demarcated ulcer forms, with a beefy-red friable base of granulation tissue. 5.[]

  • Crohn's Disease

    Painful vulval or scrotal fissures and ulceration may occur. See DermNet NZ's page on genital Crohn disease .[] The perineum should be inspected for ulceration, fistulization and abscess formation.[] Extension of intestinal Crohn disease Skin tags , swelling ( oedema ), fissures and abscesses around the perineal and perianal region are common in patients with Crohn disease[]

  • Herpes Genitalis in Women

    4-5% of ante-natal patients in the UK have a history of genital herpes. 80% is a result of infection with herpes simplex type II virus. About 50% of babies will be infected with herpes simplex if the mother has active cervical lesions. The incidence of recurrence increases towards term. Diagnosis is as in[…][]

  • Perianal Candidiasis

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  • Colonic Crohn's Disease

    BACKGROUND: Data regarding the correlation of histologic and endoscopic healing with fecal calprotectin (FC) are conflicting. We examined how FC levels correlate with histological and endoscopic remission in colonic inflammatory bowel disease. METHODS: Fifty-eight patients (23 with colonic Crohn's disease [CD] and 35[…][]

  • Pediatric Crohn's Disease

    BACKGROUND AND AIM: Childhood-onset inflammatory bowel disease (IBD) is characterized by extensive intestinal involvement and rapid early progression. Infliximab (IFX), cyclosporin (CYA), and tacrolimus (FK506) are increasingly used to treat pediatric IBD; however, their long-term effects and adverse events have not[…][]

  • Behçet Disease

    PURPOSE: Although cardiac manifestation of Behçet disease (BD) has been described in sporadic reports, its timely diagnosis remains difficult. The objective of this study was to describe early cardiac manifestations of BD. We also performed a comprehensive classification of systemic BD activity and compared their[…][]

  • Perianal Abscess

    Abstract This is a retrospective study of 78 children with perianal abscess and/or fistula in ano presenting during a 6 1/2-year period. Sixty-five were males and 13 females. Their ages at presentation ranged from 22 days to 18 years (median 1.7 year), and the majority of males were below 2 years of age. The 13[…][]

  • Anorectal Fistula

    Abstract Aim The OTSC Proctology is a surgical device for anorectal fistula closure. It consists of a super‐elastic nitinol clip, which is placed (with the aid of a transanal applicator) on the internal fistula opening to achieve healing of the fistula track. A prospective, two‐centre clinical pilot study was undertaken[…][]

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