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34 Possible Causes for Perinuclear Vacuolization of Keratinocytes

  • Familial Cutaneous Collagenoma

    HPE Hyperkeratosis Acanthosis Hypergranulosis Inc Keratohyaline Granules perinuclear vacuolization of keratinocytes s/o EHK Few inflamm cells 13.[slideshare.net]

  • Woolly Hair Nevus

    HPE Hyperkeratosis Acanthosis Hypergranulosis Inc Keratohyaline Granules perinuclear vacuolization of keratinocytes s/o EHK Few inflamm cells 13.[slideshare.net]

  • Ventral Hernia

    Characteristic vacuolated keratinocytes (koilocytes), which have a small shrunken nucleus surrounded by a perinuclear halos, are seen in the upper epidermis (figure 3).[dermnetnz.org]

  • Epidermodysplasia Verruciformis

    Keratinocytes of the upper epidermal layers are enlarged with perinuclear vacuolization and a typical blue-gray pallor.[orpha.net] A few superficial keratinocytes showed perinuclear vacuolation. Several dysplastic epidermal cells were focally present at various levels within the epidermis.[jpma.org.pk] HPVs can be detected in keratinocytes using in situ hybridization or immunohistochemistry with anti-HPV antibodies.[orpha.net]

  • Diffuse Palmoplantar Keratoderma

    Perinuclear vacuolization of keratinocytes and large irregularly shaped keratohyalin granules in the granular layer are also a feature of EPPK not seen in NEPPK.[dermaamin.com] Histologically, keratinocytes show epidermolysis, hyperkeratosis, acanthosis, and papillomatosis. Perinuclear vacuolization and large keratohyalin granules are seen.[emedicine.medscape.com]

  • Epidermal Nevus Syndrome

    HPE Hyperkeratosis Acanthosis Hypergranulosis Inc Keratohyaline Granules perinuclear vacuolization of keratinocytes s/o EHK Few inflamm cells 13.[slideshare.net] ; perinuclear vacuolization of the keratinocytes in spinous and granular layers and increased number of basophilic keratohyalin granules in the stratum granulosum.[ijdpdd.com] Figure 4: Photomicrograph showing compact hyperkeratosis and vacuolization of the keratinocytes (H&E, 10 ) Click here to view Figure 5: Photomicrograph showing compact hyperkeratosis[ijdpdd.com]

  • Verruca Vulgaris

    Characteristic vacuolated keratinocytes ( koilocytes ), which have a small shrunken nucleus surrounded by a perinuclear halos, are seen in the upper epidermis (figure 3).[dermnetnz.org] Characteristic vacuolated keratinocytes (koilocytes), which have a small shrunken nucleus surrounded by a perinuclear halos, are seen in the upper epidermis (figure 3).[dermnetnz.org]

  • Palmoplantar Keratosis

    vacuolization of the keratinocytes.[ncbi.nlm.nih.gov] Histologically, keratinocytes show epidermolysis, hyperkeratosis, acanthosis, and papillomatosis. Perinuclear vacuolization and large keratohyalin granules are seen.[emedicine.com] […] epidermolytic hyperkeratosis, consisting of a thickened granular layer with large irregularly shaped keratohyalin granules located in the granular layer of the epidermis and perinuclear[ncbi.nlm.nih.gov]

  • Ichthyosis Hystrix Type Curth-Macklin

    vacuolization and binucleated keratinocytes [ Figure 4b ].[ncbi.nlm.nih.gov] vacuolization and binucleated keratinocytes [Figure 4] b.[idoj.in] Electron microscopy shows keratin intermediate filaments forming continuous perinuclear shells, presence of perinuclear vacuoles and binucleate keratinocytes.[rarediseases.info.nih.gov]

  • Lytic Bone Lesion

    Histologically, keratinocytes show epidermolysis, hyperkeratosis, acanthosis, and papillomatosis. Perinuclear vacuolization and large keratohyalin granules are seen.[emedicine.medscape.com]

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