Create issue ticket

30 Possible Causes for Perinuclear Vacuolization of Keratinocytes

  • Erythrokeratoderma

    This is true particularly in view of histopathologic features (hyperkeratosis, acanthosis, papillomatosis, variable perinuclear vacuolation of keratinocytes, sparse perivascular[e-ijd.org]

  • Epidermal Nevus Syndrome

    HPE Hyperkeratosis Acanthosis Hypergranulosis Inc Keratohyaline Granules perinuclear vacuolization of keratinocytes s/o EHK Few inflamm cells 13.[slideshare.net] ; perinuclear vacuolization of the keratinocytes in spinous and granular layers and increased number of basophilic keratohyalin granules in the stratum granulosum.[ijdpdd.com] Figure 4: Photomicrograph showing compact hyperkeratosis and vacuolization of the keratinocytes (H&E, 10 ) Click here to view Figure 5: Photomicrograph showing compact hyperkeratosis[ijdpdd.com]

  • Familial Cutaneous Collagenoma

    HPE Hyperkeratosis Acanthosis Hypergranulosis Inc Keratohyaline Granules perinuclear vacuolization of keratinocytes s/o EHK Few inflamm cells 13.[slideshare.net]

  • Woolly Hair Nevus

    HPE Hyperkeratosis Acanthosis Hypergranulosis Inc Keratohyaline Granules perinuclear vacuolization of keratinocytes s/o EHK Few inflamm cells 13.[slideshare.net]

  • Congenital Ichthyosiform Erythroderma

    Histopathologically, it is characterized by compact hyperkeratosis, dense collections of coarse keratohyalin-like granules in the stratum granulosum and perinuclear vacuolization[saber.ucv.ve] […] of the keratinocytes in the stratums granulosum and spinosum, giving the epidermis a reticulate appearance.[saber.ucv.ve]

  • Bullous Erythroderma Ichthyosiformes

    Histopathologically, it is characterized by compact hyperkeratosis, dense collections of coarse keratohyalin-like granules in the stratum granulosum and perinuclear vacuolization[saber.ucv.ve] […] of the keratinocytes in the stratums granulosum and spinosum, giving the epidermis a reticulate appearance.[saber.ucv.ve]

  • Ichthyosis Hystrix Type Curth-Macklin

    vacuolization and binucleated keratinocytes [Figure 4] b.[idoj.in] Electron microscopy shows keratin intermediate filaments forming continuous perinuclear shells, presence of perinuclear vacuoles and binucleate keratinocytes.[rarediseases.info.nih.gov] keratinocytes.[docslide.net]

  • White Sponge Nevus

    . • Prominent hyperparakeratosis • Marked acanthosis • Vacuolization in keratinocytesPerinuclear eosinophilic condensation of epithelial cells 12.[slideshare.net] The characteristic histopathologic features are epithelial thickening, parakeratosis, a peculiar perinuclear condensation of the cytoplasm, and vacuolization of the suprabasal[burketsoralmedicine.blogspot.com] […] layer of keratinocytes.[burketsoralmedicine.blogspot.com]

  • Superficial Epidermolytic Schthyosis

    vacuolization and binucleated keratinocytes [Figure 4] b.[idoj.in] vacuolization and binucleate keratinocytes.[e-ijd.org] […] with perinuclear vacuolization in upper layers of epidermis, and coarse keratohyalin granules.[idoj.in]

  • Diffuse Palmoplantar Keratoderma

    Perinuclear vacuolization of keratinocytes and large irregularly shaped keratohyalin granules in the granular layer are also a feature of EPPK not seen in NEPPK.[dermaamin.com] Histologically, keratinocytes show epidermolysis, hyperkeratosis, acanthosis, and papillomatosis. Perinuclear vacuolization and large keratohyalin granules are seen.[emedicine.medscape.com]

Further symptoms