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207 Possible Causes for Peripheral Axonal and Demyelinating Neuropathy

  • Vitamin B12 Deficiency

    Demyelinating or axonal peripheral neuropathies can occur.[merckmanuals.com] Initial bilateral peripheral neuropathy can progress to axonal degeneration and neuronal death if left untreated.[doi.org] Subacute combined degeneration of the spinal cord involves demyelination of the posterior and lateral tracts.[doi.org]

  • Anemia

    Peripheral nervous system findings Unlike EMG/NCS findings, which indicate predominantly axonal or mixed axonal-demyelinating neuropathy, histologic examination suggests either[web.archive.org] In a recent study, up to 65% of untreated patients had peripheral neuropathy. Axonal sensorimotor polyneuropathy is present in up to 80%.[web.archive.org] Demyelinating or mixed forms are less frequent. Typical features are decreased conduction velocities and motor or sensory amplitude and denervation on EMG.[web.archive.org]

  • Neuropathy

    Axonal sensorimotor neuropathy Chronic idiopathic ataxic neuropathy Demyelinating sensorimotor neuropathy Disease related peripheral neuropathy Idiopathic chronic neuropathy[icd9data.com] In order to simplify the subsequent discussion of peripheral neuropathy, I will not distinguish axonal from demyelinating neuropathies; the discussion will apply to both types[neuropathyaction.org] Peripheral neuropathy may affect Many nerves simultaneously suggesting a diffuse process ( polyneuropathy ) Click here for Patient Education NOTE: This is the Professional[msdmanuals.com]

  • Alcohol Abuse

    Association with small fiber neuropathy and axonal large fiber peripheral neuropathy has been described.[ncbi.nlm.nih.gov] Erythromelalgia in the setting of acquired demyelinating neuropathy has not been reported.[ncbi.nlm.nih.gov]

  • Peripheral Neuropathy

    Axonal sensorimotor neuropathy Chronic idiopathic ataxic neuropathy Demyelinating sensorimotor neuropathy Disease related peripheral neuropathy Idiopathic chronic neuropathy[icd9data.com] The pathological changes of most peripheral neuropathies (axonal degeneration, segmental demyelination or a combination of these) are not specific.[neuropathology-web.org] Peripheral neuropathy may affect Many nerves simultaneously suggesting a diffuse process ( polyneuropathy )[merckmanuals.com]

  • Polyneuropathy

    Both peripheral and cranial nerves are affected, either by axonal degeneration (nerve becomes electrically inert within one week) or demyelination, which initially leaves[patient.info] Chronic symmetrical peripheral neuropathy. Multiple mononeuropathy.[patient.info] Three main patterns of polyneuropathy can be distinguished and each has a different differential diagnosis: Acute symmetrical peripheral neuropathy.[patient.info]

  • Diabetes Mellitus

    […] diabetes are caused by axonal degeneration and segmental demyelination.[emedicine.com] In contrast, some haplotypes (eg, HLA-DR2) confer strong protection against type 1 DM. [11] Sensory and autonomic neuropathy Sensory and autonomic neuropathy in people with[emedicine.com] Many factors are involved, including the accumulation of sorbitol in peripheral sensory nerves from sustained hyperglycemia.[emedicine.com]

  • Median Neuropathy

    In order to simplify the subsequent discussion of peripheral neuropathy, I will not distinguish axonal from demyelinating neuropathies; the discussion will apply to both types[neuropathyaction.org] Nerve conduction studies (NCS) are required to distinguish between these two types of neuropathies. Axonal neuropathies are more common than demyelinationg neuropathies.[neuropathyaction.org]

  • Carpal Tunnel Syndrome

    neuropathy with two forms: a demyelinating form (type 1) affecting the glia-derived myelin and an axonal form (type 2) affecting the nerve axon.[doi.org] […] screening for common mutations, including the CMT1A duplication copy-number variant and point mutations of the X-linked GJB1 gene. 9 Charcot–Marie–Tooth disease is an inherited peripheral[doi.org]

  • Ischemic Peripheral Neuropathy

    Depending on the disease associated with ischemic neuropathy, a mononeuropathy or a sensory-motor, axonal-demyelinating peripheral neuropathy may be seen as well.[ncbi.nlm.nih.gov] The underlying cause of axonal neuropathies can frequently be treated; demyelinating neuropathies are generally managed with the assistance of a neurologist.[aafp.org] Overlapping mononeuritis multiplex is a common presentation, but distal symmetric polyneuropathy and monomelic neuropathy patterns can be seen.[ncbi.nlm.nih.gov]

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