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27 Possible Causes for Peripheral Neuropathy, Splenic Metastasis, Wasting Syndrome

  • Bronchogenic Carcinoma

    neuropathy, acanthosis nigricans, and hypertrophic osteoarthropathy (Example: clubbing of fingers).[histopathology-india.net] -Look for Homer's syndrome and wasting of the small muscles of the hand. · Patient 2 has signs of pleural effusion on one side. · Patient 3 shows signs of unilateral collapse[syrianclinic.com] Neuro-myopathic: Lamber-eaton syndrome (pre-synaptic voltage gated calcium channel antibodies; SOX protein antibody; SCLC associated; treated with 3,4-diaminopyridine), Peripheral[epomedicine.com]

  • Renal Cell Carcinoma

    There have not been any cases of splenic inflammatory pseudotumors presenting or evolving with metastasis.[scielo.br] Cachexia, defined as the presence of at least 1 of these findings, was noted in 35.3% of patients.[ncbi.nlm.nih.gov] Patients with irreversible toxicity that is not reasonably expected to be exacerbated by the IMP may be included e.g. hearing loss, peripheral neuropathy etc.[clinicaltrials.gov]

  • Adenocarcinoma of the Colon

    Patients who received FOLFOXIRI had significantly more grade 3 and 4 toxicities, including neutropenia, stomatitis, and peripheral neuropathy.[cancer.gov] During an examination, he was sick-looking and wasted and had a body mass index of 20.[jmedicalcasereports.biomedcentral.com] […] sensorial neuropathy (12.4% grade 3).[cancer.gov]

  • Pancreatic Adenocarcinoma

    Tumor surrounds the superior mesenteric vein at the junction with the splenic vein. Paraaortic and celiac lymphnodes and a small liver metastasis.[radiologyassistant.nl] Osphyalgia Weight loss Cachexia or malnutrition Jaundice Anorexia Episodes of pancreatitis Nausea Emesis The evolution of imaging modality technology has positively affected[symptoma.com] The main adverse effects are peripheral neuropathy, neutropenia, thrombocytopenia and fatigue.[nature.com]

  • Malignant Gastric Neoplasm

    […] outlines (normal serpiginous pattern of the large and small bowel and physiologic hepatic and splenic uptake) (,, Fig 12b ) (, 43,, 44 ); and (b) discrete foci of uptake[doi.org] Side effects may include: tiredness nausea and vomiting nerve damage ( peripheral neuropathy ) hair loss diarrhoea anaemia (a lack of red blood cells) weight loss skin changes[nhs.uk] […] stomach from esophageal varices or at the anastomosis after surgery Intrahepatic jaundice caused by hepatomegaly Extrahepatic jaundice Inanition resulting from starvation or cachexia[emedicine.medscape.com]

  • Metastatic Ovarian Carcinoma

    Splenic metastasis primarily occurred years after surgery. Splenic metastasis was only detected in four cases when ovarian cancer was first diagnosed.[spandidos-publications.com] CASE REPORT In April 2015, a 59-year old woman was referred to the Oncological Department after onset of dyspnea, tachycardia, polypnea and cachexia.[jpmsonline.com] Findings She presented with cachexia and tympanic distended abdomen with palpable bowel loops. Body weight was 43.2kg. Vital signs were normal.[medicorcancer.com]

  • Cecal Adenocarcinoma

    ., Hemoperitonitis revealing an isolated splenic metastasis secondarily attributed to a caecal adenocarcinoma, Rev. Med.[degruyter.com] Patients who received FOLFOXIRI had significantly more grade 3 and 4 toxicities, including neutropenia, stomatitis, and peripheral neuropathy.[cancer.gov] Patients with right-side colon adenocarcinoma usually present with cachexia, weight loss, anemia, and positive fecal occult blood unlike those with left-sided colon cancers[hindawi.com]

  • Malignant Neoplasm of Pancreas

    There was no plane of separation between the mass and the splenic vein compatible with splenic vein invasion.[ijpmonline.org] […] may occur in either the central nervous system (CNS) or the peripheral nervous system (PNS).[en.wikipedia.org] The latter can occur due to the abnormal secretion of pancreatic digestive enzymes in the gastroenteric tract, poor appetite, and cachexia.[symptoma.com]

  • Skin Cancer

    BACKGROUND: To investigate the association of DNA nucleotide excision repair (NER) defects with neurological degeneration, cachexia and cancer, we performed autopsies on 4[ncbi.nlm.nih.gov] […] may occur in either the central nervous system (CNS) or the peripheral nervous system (PNS).[en.wikipedia.org] The clinical spectrum encompassed severe cachexia in the XP-A (XP12BE) patient, numerous skin cancers in the XP-A and two XP-C (XP24BE and XP1BE) patients and only few skin[ncbi.nlm.nih.gov]

  • Carcinoma of the Prostate

    Splenic metastasis. Prostate carcinomas usually occur after the age of 50, with a higher incidence after the age of 70 1.[scielo.br] […] may occur in either the central nervous system (CNS) or the peripheral nervous system (PNS).[en.wikipedia.org] Clinical examination should be thoroughly performed and may reveal cachexia, adenopathy, or an overdistended bladder.[symptoma.com]

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