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588 Possible Causes for Peripheral Neuropathy, White Matter Lesions

  • Vitamin B12 Deficiency

    Vascular risk and low serum B 12 predict white matter lesions in patients with major depression. J Affect Disord 2005 ;85: 327 – 32.[doi.org] Participation included measuring vitamin B12 levels and assessing peripheral neuropathy using Neuropathy Total Symptom Score-6 (NTSS-6) questionnaire.[ncbi.nlm.nih.gov] Vascular risk and low serum B 12 predict white matter lesions in patients with major depression. J Affect Disord. 2005; 85 :327–332. [ PubMed ] [ Google Scholar ] 48.[ncbi.nlm.nih.gov]

  • Chronic Alcoholism

    […] on the white matter.[scientificamerican.com] A consecutive sample of 62 chronic alcoholics was studied, 18 females and 44 males, aged between 28 and 69 years to assess the incidence and distribution of peripheral neuropathy[ncbi.nlm.nih.gov] The results show that alcohol-related neuropathy, especially when subclinical, seems to be frequent and mostly characterized by axonal degeneration of peripheral nerve fibres[ncbi.nlm.nih.gov]

  • Neuropathy

    If imaging shows "white matter" lesions indicating damage to myelin in nerve fibers, there is a 56 percent chance of developing MS within 10 years.[allaboutvision.com] […] management of generic peripheral neuropathy.[doi.org] Nerve damage caused by injury can also be classified as peripheral neuropathy.[neuravite.com]

  • Infectious Mononucleosis

    matter lesions.[dx.doi.org] Neurologic complications are rare but may include encephalitis, seizures, Guillain-Barré syndrome, peripheral neuropathy, viral meningitis, myelitis, cranial nerve palsies[merck.com] […] encephalopathy, seizures, visual deficits, and coma; busulfan may cause seizures; and cyclosporine is associated with confusion, aphasia, dystonia, seizures, and coma with white[dx.doi.org]

  • Fabry Disease

    The presence of white matter lesions was assessed by cerebral MRI or computed tomography (CT).[ncbi.nlm.nih.gov] Neurological complications include central nervous system involvement with cerebrovascular disease, peripheral neuropathy, and autonomic dysfunction.[ncbi.nlm.nih.gov] METHODS: In this multicentric study, we retrospectively evaluated the presence of white matter lesions (WMLs) on the FLAIR images of 104 patients with FD and 117 patients[ncbi.nlm.nih.gov]

  • Globoid Cell Leukodystrophy

    Neuroimaging at 15 years of age revealed white matter lesions, and nerve conduction velocity examinations showed a slowly developing polyneuropathy.[ncbi.nlm.nih.gov] The classic presentation includes excessive irritability, muscle hypertonicity, developmental delay, failure to thrive, peripheral neuropathy, seizures, and optic nerve atrophy[ncbi.nlm.nih.gov] […] and cerebellar white matter lesions were also detected.[ncbi.nlm.nih.gov]

  • Carbon Monoxide Poisoning

    However, in Case 2 white matter lesions persisted despite AchEI treatment.[ncbi.nlm.nih.gov] In addition, peripheral neuropathy following CO poisoning usually occurs in young adults.[ncbi.nlm.nih.gov] neuropathy, supranuclear gaze palsy and cerebral haemorrhage.[ncbi.nlm.nih.gov]

  • Systemic Lupus Erythematosus

    The cerebrospinal fluid culture was positive for LM, and magnetic resonance imaging (MRI) findings were suggestive of ependymitis and periventricular white matter lesions.[ncbi.nlm.nih.gov] GBS is an autoimmune peripheral neuropathy usually triggered by an antecedent bacterial or viral infection, with SLE being a rare cause.[ncbi.nlm.nih.gov] IFNγ-secreting myelin-specific CD8 T cells were detected exclusively in the blood of patients with NPSLE without APS but with white matter lesions.[ard.bmj.com]

  • Acute Intermittent Porphyria

    Magnetic resonance (MR) imaging demonstrated multiple large contrast-enhancing subcortical white matter lesions, which regressed with glucose and hematin infusions.[ncbi.nlm.nih.gov] The clinical presentations of abdominal pain, peripheral neuropathy and changes in mental status are the classic triad of an acute attack.[ncbi.nlm.nih.gov] Additional frequent symptoms are vomiting, hypertension, peripheral neuropathy, seizures, depression, delirium and coma.[ncbi.nlm.nih.gov]

  • Celiac Disease

    At age 34, he was diagnosed as relapsing-remitting MS upon an inflammatory CSF-syndrome and non-specific white matter lesions and treated with interferon beta-1b during the[ncbi.nlm.nih.gov] […] manifestations, thus suggesting that CD should always be considered in the differential diagnosis of peripheral neuropathy in children.[ncbi.nlm.nih.gov] Brain white matter lesions were recorded in two other studies. An association between autism and coeliac disease is disputed.[ncbi.nlm.nih.gov]

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