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10 Possible Causes for Peripheral T Cells Decreased, Raw Throat

  • Adenovirus Infection

    Appearance of virus-specific CD4 T cells in peripheral blood and a rise of neutralizing antibody titres specific for the HAdV serotype infecting the patient could be demonstrated[nature.com] An increase of lymphocyte numbers was clearly associated with a decrease of the plasma DNA load.[nature.com]

  • Food Allergy

    Reactions usually occur only when someone eats raw food. In rare cases, reactions can be life-threatening and need epinephrine.[kidswithfoodallergies.org] This causes low FOXP3 mRNA levels and markedly decreased protein expression in peripheral blood lymphocytes of affected patients.[ncbi.nlm.nih.gov] […] production of T cells.[synapse.koreamed.org]

  • Influenza

    In contrast, IL-1R1 / mice showed a dramatic decrease in CD4 T-cell proliferation, suggesting that efficient T-helper cell priming in peripheral organs is dependent on a functional[dx.doi.org] As expected, we found a strong antigen-specific proliferation of CD4 T cells from wild-type mice (Fig. 5 ).[dx.doi.org]

  • Pemphigus

    Blisters form in the throat as well. Blisters can form on the skin and rupture, leaving raw, painful, crusted wounds. The person feels generally ill.[merckmanuals.com] Immunologic Evaluations Peripheral-blood B- and T-lymphocyte subpopulations and T-lymphocyte cytokine production were analyzed longitudinally.[doi.org] Pemphigus vulgaris may cause severe blistering of the skin and the mucous membranes lining the mouth, nose, throat, eyes and genital area.[bad.org.uk]

  • Septic Shock

    The patient presented a remarkable cell activation profile and diminished percentage of peripheral blood T regulatory cells.[ncbi.nlm.nih.gov] A decrease in anti-inflammatory IL-1RA plasma level showed the potential for endothelium damage, probably contributing to a vasculitis process.[ncbi.nlm.nih.gov]

  • Chronic Thyroiditis

    Areas of thyroid with active cells and colloid-poor follicles look like raw beef.[pathguy.com] Estrogen decreases the CD4 /CD8 T cell ratio and TNF-α cytotoxicity in T cells and increases immunoglobulin secretion, B cell survival, and polyclonal activation of B cells[journal.frontiersin.org] * "Globus hystericus" ("a lump in my throat") is often emotionally-based but be sure not to miss a goiter or thyroid nodule (J. Laryngol. Otol. 121 : 242, 2007).[pathguy.com]

  • Chronic Fatigue Syndrome

    […] ratio, indicating a T H 2 shift. 50 When peripheral blood mononuclear cells from CFS patients are stimulated in culture, increased IL-4 levels accompany a high T H 2/T H 1[ncbi.nlm.nih.gov] A well-studied and characteristic finding is an attenuated T H 1 response. 47 – 49 Some adolescents with CFS exhibit increased levels of IL-10 and a decreased IFN-γ/IL-10[ncbi.nlm.nih.gov] […] ratio. 51 Studies revealing decreases in T H 1 and T H 17 inflammatory mediators may begin to provide links to the declining neurocognitive function and depressed psychosocial[ncbi.nlm.nih.gov]

  • Cytomegalovirus

    A, CD8 T-cell counts in the peripheral blood of patients decrease following DI-TMZ cycle 1 from pheresis-1 to vaccine-1 ( P 0.020) and steadily increase with sequential vaccination[clincancerres.aacrjournals.org] Sequential pp65-DC vaccination expands peripheral CD8 T cells and CD8:Treg ratios but does not affect conventional CD4 counts or CD4:Treg ratios.[clincancerres.aacrjournals.org] C, Conventional CD4 T-cell counts in the peripheral blood of patients dramatically diminish following DI-TMZ cycle 1 ( P 0.037) and do not increase following sequential pp65[clincancerres.aacrjournals.org]

  • Acquired Immunodeficiency Syndrome

    Monoclonal antibody analysis of peripheral-blood T-cell subsets revealed a marked decrease of the T-helper cell subset with inversion of the normal ratio of T-helper to T-suppressor[web.archive.org] Immunologic studies at CDC on specimens from the 11 patients tested showed severe T-cell dysfunction.[web.archive.org]

  • Chronic Infection

    Symptoms include a raw or tickling sensation in the back of the throat and there may be difficulty swallowing. Sometimes these symptoms are accompanied by a fever.[primaryimmune.org] A recent study showed that patients with CAEBV or infectious mononucleosis have a decrease in the TCR-beta repertoire and expanded T cell clones in their peripheral blood[ncbi.nlm.nih.gov] Pharyngitis - Pharyngitis describes an inflammation of the throat (sore throat).[primaryimmune.org]

Further symptoms