Retinal examination shows atrophy of the nerve fiber layer and necrosis of other superficial retinal layers. The disease has a marked predilection of HLA-B51.
Endothelial cell proliferation is also present and together these lead to the occlusion of small blood vessels.
The underlying pathology for all Behcet’s lesions is occlusive vasculitis with marked perivascular infiltration of lymphocytes and mononuclear cells.
The pathological vascular crossing is caused by proliferation of the perivascular glial cells and swelling of the nerve fibers [ 6 ].