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46 Possible Causes for Pernicious Anemia, Recurrent Urinary Tract Infection, Splenomegaly

  • Myelodysplasia

    Therapy with granulocyte-colony stimulating factor (G-CSF) and granulocyte-monocyte-colony stimulating factor (GM-CSF) caused splenomegaly and severe thrombocytopenia, which[ncbi.nlm.nih.gov] , agranulocytosis, hemolytic anemia, pernicious anemia, and paroxysmal nocturnal hemoglobinuria.[ncbi.nlm.nih.gov] We present a 2-year-old boy with splenomegaly, leukocytosis, thrombocytopenia, anemia, and excess myeloblasts with easily seen Auer rods, and marked dysgranulopoiesis and[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[ncbi.nlm.nih.gov] [About the relationship between the most lethal blood poisons and degradation products of proteins: a contribution to the etiology of pernicious anemia]. Kollek. Klin.[doi.org] Significant thrombopenia ( KEYWORDS: Myelofibrosis; Palliation; Splenic irradiation; Splenomegaly[ncbi.nlm.nih.gov]

  • Systemic Lupus Erythematosus

    […] relapsing illness, with a variety of different presentations. [ 5 , 6 ] Symptoms and signs are often nonspecific - eg, fatigue (can be severe and debilitating), malaise, fever, splenomegaly[patient.info] She was diagnosed with SLE with pernicious anemia and iron deficiency anemia. The rare association of SLE with pernicious anemia was reported previously in few patients.[ncbi.nlm.nih.gov] […] relapsing illness, with a variety of different presentations. [ 5, 6 ] Symptoms and signs are often nonspecific - eg, fatigue (can be severe and debilitating), malaise, fever, splenomegaly[patient.info]

  • Pancytopenia

    The patient had a history of recurrent CDI, recurrent urinary tract infections, nephrolithiasis, chronic hepatitis C, and endometriosis.[ncbi.nlm.nih.gov] […] macrocytic anaemia (haemoglobin, 5.1 g/dL; mean corpuscular volume, 116 fL) in addition to leucopenia and thrombocytopaenia (pancytopenia), icterus secondary to haemolysis and splenomegaly[ncbi.nlm.nih.gov] Extensive workup revealed vitamin B12 deficiency secondary to pernicious anemia.[journalmc.org]

  • Primary Immune Deficiency Disorder

    In addition to pulmonary infection, M pneumoniae can also cause primary infection in the urinary tract and joints.[emedicine.medscape.com] , vitiligo, or pernicious anemia may signal a disorder of the immune system.[mountsinai.org] Hepatomegaly and splenomegaly may be detected in the abdomen. In infants, crusting around the anus may be a sign of chronic diarrhoea.[patient.info]

  • Splenic Vein Thrombosis

    The patient had a history of facial swelling, edema and recurrent upper respiratory tract infections since two years of age.[sjkdt.org] Seven of 9 patients (78 %) with massive splenomegaly ( 20 cm) developed PSVT compared with 4 of 13 patients (31 %) with moderate splenomegaly (15-20 cm) and 6 of 45 patients[ncbi.nlm.nih.gov] An abdominal imaging scan showed that he had concomitant pernicious anemia and concomitant portal, superior mesenteric and splenic vein thrombosis.[ncbi.nlm.nih.gov]

  • Lipodystrophy

    There were 6 events of urinary tract infection (UTI) occurring in 2 patients with a history of recurrent UTI.[omicsonline.org] See Atlas 2, Part F.) congenital generalized lipodystrophy an autosomal recessive condition marked by the virtual absence of subcutaneous adipose tissue, large body size, splenomegaly[medical-dictionary.thefreedictionary.com] anemia.[healio.com]

  • Thalassemia

    Renal abnormalities (hydronephrosis, renal hypoplasia or agenesis, polycystic kidney, vesico-ureteric reflux) may present with recurrent urinary tract infections.[ojrd.com] Approach to the adult patient with splenomegaly and other splenic disorders. . Accessed June 14, 2016. Splenomegaly. Merck Manual Professional Version. .[mayoclinic.org] Conditions leading to anemia caused by vitamin deficiency include: Megaloblastic anemia : Vitamin B12 or folate or both are deficient Pernicious anemia : Poor vitamin B12[webmd.com]

  • Hypogammaglobulinemia

    We describe a patient with low immunoglobulin levels due to carbamazepine use who presented with recurrent urinary tract infection.[ncbi.nlm.nih.gov] Lymphoproliferative disorders such as generalized lymphadenopathy and/or splenomegaly are present in up to 40% of patients, and there is an increased risk of developing gastrointestinal[orpha.net] Gastritis with achlorhydria and pernicious anemia may occur.[emedicine.medscape.com]

  • Salmonella Infection

    Compared with previous reported cases in renal transplantation, patients with heart transplantation had low rates of urinary tract infection and recurrence.[ncbi.nlm.nih.gov] Conditions of hypoacidity, which may occur among infants, in pernicious anemia, or with the use of antacid medications, increase the risk of infection.[online.epocrates.com] There was no recurrence in 3 survivors.[ncbi.nlm.nih.gov]

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