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465 Possible Causes for Persistent Notochordal Canal, Proximal Muscle Weakness Limb Girdle Distribution, Stiffness of the Lower Limbs

  • Infantile-Onset Ascending Hereditary Spastic Paralysis

    These disorders are characterized by muscle stiffness (spasticity) and weakness in the lower limbs (paraplegia).[icdlist.com] notochordal canal syndrome Salla disease Salt-and-pepper syndrome Sandhoff disease Sandhoff disease, adult form Sandhoff disease, infantile form Sandhoff disease, juvenile[se-atlas.de] These disorders are characterized by progressive muscle stiffness (spasticity) and eventual paralysis of the lower limbs (paraplegia).[ghr.nlm.nih.gov]

    Missing: Proximal Muscle Weakness Limb Girdle Distribution
  • Arthritis

    Because there are several types of arthritis, it’s important to know which one you have. There are some similarities between these conditions, but there are also some key differences. Osteoarthritis The most common type of arthritis is osteoarthritis. It is estimated that around 8.75 million people in the UK have[…][arthritisresearchuk.org]

    Missing: Persistent Notochordal Canal Proximal Muscle Weakness Limb Girdle Distribution
  • Meningomyelocele

    This can result in numbness, unbalanced walking, painless skin lesions, stiffness and pain in the lower limbs and back, sometimes relieved with odd postures or lying down.[amardeepchildrenhospital.com] […] splits around that adhesion or persistence of the neurenteric canal, which would leave a connection of pluripotent cells between the ectoderm and the endoderm. [8] The role[asianjns.org] […] theories postulated are neoplastic transformation of misplaced primordial germ cells from the yolk sac, an ectodermal-to-endodermal adhesion forms during gastrulation and the notochord[asianjns.org]

    Missing: Proximal Muscle Weakness Limb Girdle Distribution
  • Lower Motor Neuron Syndrome with Late-Adult Onset

    Weakness progresses to the forearms, shoulders, and lower limbs.[msdmanuals.com] notochordal canal syndrome Salla disease Salt-and-pepper syndrome Sandhoff disease Sandhoff disease, adult form Sandhoff disease, infantile form Sandhoff disease, juvenile[se-atlas.de] When upper motor neurons are affected the manifestations include spasticity or stiffness of limb muscles and overactivity of tendon reflexes such as knee and ankle jerks.[advancedpsy.com]

    Missing: Proximal Muscle Weakness Limb Girdle Distribution
  • Congenital Malformation of the Spine

    Neurological assessment revealed myelopathic gait with bilateral upper limb and lower limb hyperreflexia, bilateral Babinski sign and Hoffman’s reflex present.[jss.amegroups.com] Around the third week of gestation, when the cells from Hensen’s node are proliferating and migrating, there may be a focal splitting of the notochord secondary to a persistent[radiologykey.com] There was no history of trauma, any joint stiffness, fever, weight loss or stigmata of tuberculosis.[jss.amegroups.com]

    Missing: Proximal Muscle Weakness Limb Girdle Distribution
  • Neonatal Adrenoleukodystrophy

    Symptoms may include progressive stiffness, weakness, or paralysis of the lower limbs and loss of coordination. Brain function deterioration may also been seen.[medical-dictionary.thefreedictionary.com] Adult-onset symptoms, which usually develop between the ages of 21 and 35, may include progressive stiffness, weakness or paralysis of the lower limbs, and loss of coordination[applecratenc.com]

    Missing: Persistent Notochordal Canal Proximal Muscle Weakness Limb Girdle Distribution
  • Polymyalgia Rheumatica

    Definition Polymyalgia rheumatica (PMR) is an inflammatory disorder that causes widespread muscle aching and stiffness, primarily in your neck, shoulders, upper arms, thighs and hips. Although some people develop these symptoms gradually, polymyalgia rheumatica can literally appear overnight. People with polymyalgia[…][web.archive.org]

    Missing: Persistent Notochordal Canal Proximal Muscle Weakness Limb Girdle Distribution
  • Spinal Stenosis

    Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a potentially disabling disorder. Little is known about the contributors to severe forms of the illness. We describe three consecutive patients with severe ME/CFS whose symptoms improved after recognition and surgical management of their cervical spinal[…][ncbi.nlm.nih.gov]

    Missing: Persistent Notochordal Canal Proximal Muscle Weakness Limb Girdle Distribution
  • Lumbar Osteoarthritis

    Pain on weight-bearing if the lower limb joints are involved.[arthritis.co.za] It can occur in any joint, but is most commonly seen in selected joints of the hand, spine, and lower limb.[bmcmusculoskeletdisord.biomedcentral.com] Stiffness after rest - called gelling - usually lasting less than 5 minutes - with the patient loosening up quickly by moving the joints.[arthritis.co.za]

    Missing: Persistent Notochordal Canal Proximal Muscle Weakness Limb Girdle Distribution
  • Heelspur

    […] tissue massage or release, muscle flexibility or stretches, foot taping, foot, and lower limb strengthening exercises and occasionally night splints.[physioworks.com.au] Depending upon your specific clinical assessment, your physiotherapist may provide you with manual therapy techniques such as joint mobilisations to loosen stiff joints, soft[physioworks.com.au]

    Missing: Persistent Notochordal Canal Proximal Muscle Weakness Limb Girdle Distribution