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245 Possible Causes for Pharyngeal Muscle Weakness

  • Oculopharyngeal Muscular Dystrophy

    Evidence of pharyngeal muscle weakness often occurs concomitantly with the ocular signs (43%). Ptosis occurs first in 43% and dysphagia first in 14%.[disorders.eyes.arizona.edu] Interestingly, the degree of myopathic changes was more prominent in the eyelid and pharyngeal muscles.[ncbi.nlm.nih.gov] Proximal limb muscle weakness and gait abnormalities were common and occurred later than ocular or pharyngeal weakness.[jamanetwork.com]

  • Myasthenic Crisis

    In MG patients, the pharyngeal and laryngeal muscles are weak, thus causing difficulty when swallowing; often patients appear to be choking.[journal.frontiersin.org] The characteristic pattern of muscle fatigue and weakness typically involves ocular, facial, pharyngeal, and proximal limb muscles. 5 Although variable with respect to age[journals.lww.com] By this time, her pharyngeal, laryngeal, respiratory, and limb muscles were all affected.[journal.frontiersin.org]

  • Amyotrophic Lateral Sclerosis

    In some patients the first sign of weakness is difficulty swallowing or eating due to involvement of the tongue or pharyngeal muscles (bulbar onset ALS).[medicine.yale.edu] Eventually the weakness spreads to involve all four extremities, the muscles of the trunk and abdomen, and the bulbar muscles of the face, mouth, and throat.[medicine.yale.edu]

  • Syringobulbia

    With extension into the medulla (syringobulbia), symptoms may include dysphagia, nystagmus, pharyngeal and palatal weakness, tongue atrophy, and sensory loss in the trigeminal[now.aapmr.org] Lumbar syringomyelia can cause leg muscle atrophy with dissociated sensory loss in lumbosacral dermatomes, with decreased or absent reflexes.[now.aapmr.org]

  • Perry Syndrome

    […] of swallowing movements, but by specific pharyngeal muscle weakness.[karger.com] […] in the 2 PS patients suggest that muscle weakness, rather than impaired coordination of swallowing movements, causes difficulty in passing the bolus through the pharynx.[karger.com] In contrast to the findings in idiopathic PD [ 10 ], the pharyngeal retention on VF and decreased pharyngeal pressure but normal duration of the swallowing reflex on manometry[karger.com]

  • Epidermolysis Bullosa Simplex

    He was re-evaluated at age 17 and demonstrated significant ptosis, ophthalmoparesis, and pharyngeal muscle weakness.[ncbi.nlm.nih.gov]

  • Botulism

    Botulinum toxins are potent neurotoxins used in a variety of neurological disorders. Few pediatric reports have been published to date regarding the potential hazards of therapeutic use of botulinum toxins. We describe the case of a 10-year-old boy who developed systemic weakness following treatment of spasticity[…][ncbi.nlm.nih.gov]

  • Esophageal Achalasia

    Achalasia is rare motor disorder of esophageal smooth muscle. It has been linked to malnutrition during pregnancy leading to maternal and fetal mortality. We report a case of achalasia with intrauterine fetal death who succeeded in following pregnancy with good fetal and maternal outcome after operative treatment.[…][ncbi.nlm.nih.gov]

  • Esophagitis

    The patient was a 76-year-old woman who had noticed slight difficulty in swallowing in the 3 years prior to this presentation. Her dysphagia progressed while she was hospitalized following cervical cancer surgery. Esophagogastroduodenoscopy and an esophagram showed circumferential erosion and a stricture of the[…][ncbi.nlm.nih.gov]

  • Corynebacterium Diphtheriae

    A 6-year-old boy presented to a university hospital in Malaysia with infective endocarditis complicating cyanotic congenital heart disease. Blood cultures showed a gram-positive, aerobic, coryneform-like bacillus identified by the hospital laboratory as Corynebacterium xerosis, but a reference laboratory identified the[…][ncbi.nlm.nih.gov]

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