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5,346 Possible Causes for phosphates

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  • Tumor Lysis Syndrome

    The serum phosphate reduced to normal levels within 24-48 hrs of initiation of sevelamer hydrochloride.[] Treatment of hyperphosphatemia reduces dietary phosphate intake and includes phosphate binders such as aluminum hydroxide and aluminum carbonate.[] The pathophysiology involves massive tumor cell lysis resulting in the release of large amounts of potassium, phosphate, and uric acid.[]

  • Tumoral Calcinosis

    Medical treatments are targeted toward decreasing intestinal phosphate absorption or increasing phosphate excretion; however, results have been variable and generally limited[] […] the phosphate regulator protein FGF23, impairing its ability inhibit reabsorption of filtered phosphate in the kidneys.[] The patient was treated with withdrawal of vitamin D therapy, strict control of serum phosphate levels with noncalcemic phosphate binders, and subtotal parathyroidectomy.[]

  • Hyperphosphatemia

    A low phosphate diet, an efficient dialysis removal of phosphate load, and the administration of phosphate binders are the main recommended steps to control hyperphosphatemia[] She was treated conservatively with oral phosphate binders and made an uneventful recovery.[] The authors described a patient with HP due to a phosphate-binding immunoglobulin (Ig).[]

  • Vitamin D Deficiency

    In stage 1 VDDR, urinary amino acid and phosphate excretion are normal with minimal or no findings of rickets on radiographs.[] Serum calcium, phosphate, PTH, LIC, cardiac T2 * , and LVEF were not different between the groups with or without Vitamin D deficiency.[] […] here presented for evaluation of bowing of his lower extremities, and was ultimately diagnosed with X-linked hypophosphatemic rickets, a disorder caused by renal wasting of phosphate[]

  • Hereditary Fructose Intolerance

    The radioactive fructose-1-phosphate compound was prepared from [U-14C]fructose by use of partly purified fructokinase (EC[] It was found that fructose 1-phosphate is a potent competitive inhibitor (Ki congruent to 40 microM) of phosphomannose isomerase (EC, the first enzyme of the N-glycosylation[] Fructose-1 -phosphate (F-1-P), the initial reaction product of administered fructose, accumulates intracellularly behind this enzymatic defect 4, much as galactose-1-phosphate[]

  • Nephrocalcinosis

    In vitro studies showed that the p.Arg495His mutation resulted in decreased phosphate uptake when compared to wild-type SLC34A1.[] In this study, we wanted to elucidate whether the histopathological appearance of calcium phosphate deposits provides information about possible etiology.[] We found the increased phosphate dose administered for treatment to play a role in nephrocalcinosis development.[]

  • Carbamoyl Phosphate Synthetase Deficiency

    Mutations in the CPS1 gene cause carbamoyl phosphate synthetase I deficiency. The CPS1 gene provides instructions for making the enzyme carbamoyl phosphate synthetase I.[] […] carbamoyl phosphate.[] Title Other Names: Hyperammonemia due to carbamoyl phosphate synthetase 1 deficiency; CPS 1 deficiency; Carbamyl phosphate synthetase (CPS) deficiency Categories: This disease[]

  • Calciphylaxis

    We report on a 21-month-old girl with end-stage renal disease with severe calcium-phosphate imbalance.[] Conservative principles for management include normalization of calcium phosphate levels and local wound care. Penectomy may not impact survival.[] (8.2 versus 5.7 mg/dl; p 0.001), calcium phosphate product (81.5 versus 52.9; p 0.0004), parathyroid hormone (1496 versus 138 pg/ml; p 0.0001), and alkaline phosphatase levels[]

  • Pulmonary Alveolar Microlithiasis

    Inactivating mutations in SLC34A2, which encodes the NPT2b sodium-dependent phosphate cotransporter, has been proposed as a cause of PAM.[] Whole-lung EDTA can reduce the burden of stones in the lungs, and a low-phosphate diet prevents stone formation.[] PAM has been reported to arise from inactivating mutations in SLC34A2, encoding a sodium-dependent phosphate co-transporter essential for phosphate transport in the lungs[]

  • Disorder of Fructose Metabolism

    The two triose phosphates, Dihydroxyacetone phosphate and glyceraldehyde 3-phosphate, may be degraded by glycolysis or may be substrates for aldolase and hence gluconeogenesis[] -1-phosphate.[] Gal actose 1 phosphate is converted to Glu cose 1 phosphate by Galactose 1 phosphate U ridyl transferase (the letter U ).[]

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