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341 Possible Causes for Pigment Clumping

  • Pigmented Paravenous Retinochoroidal Atrophy

    Abstract A patient had bilateral macular coloboma with aggregations of pigment clumps located perivascularly, predominantly paravenously, and in other parts of the retina.[] Fluorescein angiography showed hyperfluorescence due to the pigment epithelial atrophy together with hypofluorescence corresponding to bone spicule pigment clumping.[] The diagnosis of bilateral macular coloboma with pigmented paravenous retinochoroidal atrophy was made and seemed to be a developmental abnormality in origin.[]

  • Goldmann-Favre Syndrome

    […] nummular pigment clumping and atrophy at level of RPE (Fig. 1e) 18 M 32 OD: 6/9 ND Constricted visual fields Left macular cysts OS: 6/9 Mid-peripheral nummular pigment clumping[] Clumped pigment deposits were recognized in the patients with ESCS and GFS. The CPRD patients without NR2E3 mutations had no detected mutations in NRL or THRB1.[] (A) Fundus of the right eye shows lamellar macular holes with microcystic spaces and clumping of retinal pigment epithelium.[]

  • Strabismus

    RESULTS: Color fundus photography showed a sharply-demarcated, round macular defect, approximately 4 4 disc diameters with bare sclera at the base and pigment clumping in[]

  • Sorsby's Fundus Dystrophy

    Progressive retinal pigment epithelial atrophy and peripheral pigment clumping occurred in elderly relatives who lost ambulatory vision.[]

  • Autosomal Dominant Rhegmatogenous Retinal Detachment

    It is characterized by yellow-orange lesions with surrounding darker border and pigment clumping, bilateral and symmetrical.[] ‘Dry Type’: Drusen and associated retinal pigment epithelial changes (atrophy and clumping). The majority of these eyes have moderate visual disturbance.[] Adult Vitelliform Macular Dystrophy (AVMD) AVMD presents smaller lesions than Best disease, without disruption or layering of the yellow pigment and occurs in old patients[]

  • Central Areolar Choroidal Dystrophy

    Interindividual phenotypic variability was apparent and ranged from predominantly drusenlike depositions to single perifoveal pigment clumps.[] The presence of drusen and pigment clumping was determined with color fundus photography. High-resolution in vivo imaging was performed with cSLO and SD-OCT.[] The enlargement of the geographic lesion was associated with an increase in pigment clumps and in the visibility of choroidal vessels.[]

  • Retinitis Pigmentosa

    clumping, and contraction of the visual field Applies To Retinal dystrophy, albipunctate Retinitis pigmentosa ICD-9-CM Volume 2 Index entries containing back-references to[] The classic sign of RP is clumps of pigment in the peripheral retinal called "bone-spicules."[] SignsSigns  Pigment clumpsPigment clumps  Optic atrophyOptic atrophy  Macular atrophyMacular atrophy 27.[]

  • Myopic Macular Degeneration

    One of the most common early signs of macular degeneration is the presence of drusen -- tiny yellow deposits under the retina -- or pigment clumping.[] clumping, and sometimes hyperpigmentation in association with fibrosis and retinal atrophy is present.(13) Among myopic patients with pre-existing CNV, more than 30% will[] […] unclear, however, what causes the growth of new-vessels through the breaks in Bruch's membrane.(12) In advanced stage, CNV appears as a Fuchs' spot that is a macular scar with pigment[]

  • Peripheral Vasoproliferative Retinopathy

    Figure 10-19: Retinitis pigmentosa with arteriolar narrowing and peripheral retinal pigment clumping.[] The most characteristic ophthalmoscopic findings are narrowing of the retinal arterioles, mottling of the retinal pigment epithelium, and peripheral retinal pigment clumping[]

  • Macular Degeneration

    One of the most common early signs of macular degeneration is the presence of drusen -- tiny yellow deposits under the retina -- or pigment clumping.[] In macular degeneration, clumps of yellowish cellular debris--possibly of retinal origin--gradually accumulate within and beneath the retinal pigment epithelium.[] These vessels supply oxygen and nutrients to the retinal pigment epithelium and photoreceptor cells and carry away waste products.[]

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