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437 Possible Causes for Pigment Clumping

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  • Nephronophthisis

    Areas of bone-corpuscle pigment clumping may be seen sectorially in the periphery or throughout the fundus, and is associated with arteriolar narrowing.[] The clinical picture has been: normal disos and retinal vessels, fine pigment clumping in the equatorial region."[]

  • Retinitis Pigmentosa with Situs Inversus

    Retinal vessels were attenuated, and there were few scattered pigment clumping in the periphery of each eye.[]

  • Bardet-Biedl Syndrome 2

    Fundus showed a waxy pale disc with marked attenuation of arterioles and pigmented clumps at the periphery suggestive of atypical retinitis pigmentosa [Figure 2] a and [Figure[]

  • Choroid Disease

    Also, may contain lipofuscin pigment clumping, folds, subretinal fluid, detachments, vitreous hemes, secondary cataracts, choroidal neovascularization.[] Progression of the disease leads to pigment clumping, RPE and choriocapillaris atrophy, and eventual total atrophy of the choroid exposing the white sclera.[] The disease is often recognizable on examination by the narrowing of retinal vessels and the scattering of clumps of pigment throughout the retina.[]

  • Amblyopia

    Fundus examination did not reveal any abnormalities in the right eye, but narrow retinal vessels, optic disc pallor, and peripheral retinal pigment clumping was found in the[]

  • Ophthalmoplegia

    A related mitochondrial myopathy is the Kearns-Sayre syndrome in which there is CPEO, a type of retinitis pigmentosa characterized by coarse pigment clumping which principally[]

  • Idiopathic anterior Uveitis

    Circular pigment clumping on the anterior capsule is a sign of previous episodes of synechia and therefore uveitis.[]

  • Autosomal Recessive Spastic Paraplegia Type 48

    The far periphery shows black pigment clumping (hashtag). Discs show mild temporal pallor. An EMG/NCS indicated an axonal sensory polyneuropathy.[] Choroidal depigmentation and pigment clumping around the optic nerves as well as in several areas in the mid-periphery, with thinning of the nerve fiber layers in both eyes[]

  • Proliferative Vitreoretinopathy

    clumps or clusters on the retina Wrinkling of inner retina, retinal stiffness associated with decreased mobility of the vitreous Full thickness, fixed folds which may be[] Table 2: Classification of Proliferative Vitreoretinopathy, 1991 Grade Features A Vitreous haze, vitreous pigment clumps, pigment clusters on inferior retina B Wrinkling of[] Grade 0 included not only normal retina but also vitreous haze as well as pigment clumps on retina or vitreous (SSCS PVR grade A). ( Bottom ) PVR grade of animals on days[]

  • Retinal Telangiectasia

    Pigment clumps with a whitish discoloration are seen to the right of the macular center.[] In stage 4, black retinal pigmented epithelial hyperplasia, or clumps around the right-angled venules, are seen.[] Discussion Macular telangiectasia type 2 is a rare, typically bilateral condition characterised by perifoveal telangiectatic vessels, pigment clumping, crystalline deposits[]

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