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12 Possible Causes for PLED Bilaterally

  • Traumatic Brain Injury

    Cochrane Database of Systematic Reviews Background Raised intracranial pressure (ICP) is an important complication of severe brain injury, and is associated with high mortality. Barbiturates are believed to reduce ICP by suppressing cerebral metabolism, thus reducing cerebral metabolic demands and cerebral blood[…][doi.org]

  • Meningoencephalitis

    Lancet Infect Dis. 2016 Nov;16(11):e261-e266. doi: 10.1016/S1473-3099(16)30162-1. Epub 2016 Sep 16. Author information 1 Department of Paediatric Haematology, Immunology and Infectious Diseases, Emma Children's Hospital, Academic Medical Center, Amsterdam, Netherlands; Department of Paediatrics, Onze Lieve Vrouwe Gasthuis,[…][ncbi.nlm.nih.gov]

  • Encephalitis

    Encephalitis is inflammation of the brain. Severity is variable. Symptoms may include headache, fever, confusion, a stiff neck, and vomiting. Complications may include seizures, hallucinations, trouble speaking, memory problems, and problems with hearing.Causes of encephalitis include viruses such as herpes simplex virus[…][en.wikipedia.org]

  • Herpes Simplex Encephalitis

    The EEG findings usually parallel the imaging abnormalities with focal slowing, periodic lateralized discharges (PLEDS), bilateral independent PLEDS (BiPLEDS) and occasionally[omicsonline.org] EEG revealed PLEDS and cranial MRI revealed bilateral temporal hyperintensities on T2 weighted images. Rising antibody titers and PCR confirmed HSE.[neurologyindia.com] The epileptiform abnormalities were bilateral in five (18%). CEREBROSPINAL FLUID The leucocyte count in the CSF ranged between 0 and 930 10 6 /l.[jnnp.bmj.com]

  • Encephalopathy

    Encephalopathy (; from Ancient Greek: ἐνκέφαλος "brain" πάθος "suffering") means any disorder or disease of the brain, especially chronic degenerative conditions. In modern usage, encephalopathy does not refer to a single disease, but rather to a syndrome of overall brain dysfunction; this syndrome can have[…][en.wikipedia.org]

  • Intoxication

    […] microorganisms THIS IS A DIRECTORY PAGE. Britannica does not currently have an article on this topic. Learn about this topic in these articles: meat spoilage In meat processing: Food-poisoning microorganisms […]cause health problems by either intoxication or infection. Intoxication occurs when food-poisoning[…][britannica.com]

  • Stupor

    Several EEG patterns and their interpretation in suspected cases of NCSE such as periodic lateralized epileptiform discharges (PLEDs), bilateral independent periodic lateralized[ncbi.nlm.nih.gov]

  • Acute Subdural Hematoma

    Poor early outcomes were associated with the presence of bilateral (P 0.03), midline (P 0.04), and bilateral independent multifocal discharges (P 0.09) on EEG.[ncbi.nlm.nih.gov] […] patients (87%) had epileptiform discharges on EEG; 13 of them (62%) had midline epileptiform discharges and 9 of them (43%) had periodic lateralized epileptiform discharges (PLEDs[ncbi.nlm.nih.gov]

  • Persistent Vegetative State

    This consensus statement of the Multi-Society Task Force summarizes current knowledge of the medical aspects of the persistent vegetative state in adults and children. The vegetative state is a clinical condition of complete unawareness of the self and the environment, accompanied by sleep-wake cycles, with[…][ncbi.nlm.nih.gov]

  • Vegetative State

    Use of botulinum toxin is expanding as clinical studies demonstrate new potential therapeutic applications. In rehabilitation, botulinum toxin is predominantly used as adjunct therapy for the treatment of spasticity, but it may prove useful for other atypical clinical situations. A 73-year-old man had a severe[…][ncbi.nlm.nih.gov]

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