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26 Possible Causes for Pleural Effusion, Polyclonal Hyperglobulinemia

  • Multicentric Castleman's Disease

    Nevertheless, his general condition, including pleural effusion and ascites, worsened, and C-reactive protein and interleukin-6 levels showed marked increases.[ncbi.nlm.nih.gov] hyperglobulinemia, elevated transaminases and renal disease. 2 , 5 , 7 Dispenzieri et al. 8 analyzed the clinical spectrum of Castleman’s disease in 113 patients.[pagepress.org] Patients with MCD may reveal raised serum C-reactive protein level, polyclonal hyperglobulinemia, anemia of microcytic hypochromic nature, low albumin level, and high cholesterol[lungindia.com]

  • Primary Myelofibrosis

    The condition may result in spinal cord compression, focal seizures, symptoms related to brain tumours, ascites, haematuria, pericardial effusion, pleural effusion, haemoptysis[patient.info] Polyclonal hyperglobulinemia may be present. Patients with sporadic idiopathic or familial pulmonary hypertension have significant marrow fibrosis.[patient-help.com] The condition may result in GI tract hemorrhage, spinal cord compression, focal seizures, symptoms related to brain tumors, ascites, hematuria, pericardial effusion, pleural[emedicine.medscape.com]

  • Castleman Disease

    A thoracic radiography can show a wide mediastinum or pleural effusions.[symptoma.com] The disease is characterized by fever, weight loss, anemia, polyclonal hyperglobulinemia, splenomegaly, thrombocytosis and peripheral lymphadenopathy.[ncbi.nlm.nih.gov] , hypoalbuminemia, polyclonal hypergammaglobulinemia, leukocytosis, thrombocytosis or splenomegaly. 1,4 In contrast to the localized form, the clinical course of the multicentric[scielo.br]

  • Angioimmunoblastic Lymphadenopathy

    Occasionally, pulmonary involvement, including pleural effusion, has also been observed. Two cases of AILD accompanied by pleural effusion are reported here.[ncbi.nlm.nih.gov] In one series, other symptoms included weight loss (58%), hepatomegaly (60%), polyclonal hyperglobulinemia (65%), and generalized adenopathy (87%).[emedicine.medscape.com] Chest radiography and computed tomography demonstrated a loss of volume of the right lung caused by intrathoracic lymphadenopathy and a pleural effusion.[ncbi.nlm.nih.gov]

  • Rosai-Dorfman Disease

    effusions.[ncbi.nlm.nih.gov] hyperglobulinemia.[ncbi.nlm.nih.gov] Conclusions: Intrathoracic manifestations of RDD are relatively common and include mediastinal lymphadenopathy, airway disease, pleural effusion, cystic and interstitial lung[mayoclinic.pure.elsevier.com]

  • Autoimmune Pancreatitis

    effusions CBD: strictures mediastinal nodes MRI MRI demonstrates diffuse pancreatic enlargement 5,10 .[radiopaedia.org] hyperglobulinemia.[hematologyandoncology.net] Note right pleural effusion. Surgical pathology confirmed IgG4-positive lymphoplasmacytic infiltration.[ajronline.org]

  • Pyoderma

    […] gangrenosum pleural effusion View Full Text Statistics from Altmetric.com pyoderma gangrenosum pleural effusion Pyoderma gangrenosum is an unusual skin disease of unknown[thorax.bmj.com] Monoclonal or polyclonal hyperglobulinemia may also be associated with PG.[ 3 ] However, the immunological abnormalities associated with PG are not always consistently observed[ncbi.nlm.nih.gov] […] gangrenosum pleural effusion Statistics from Altmetric.com pyoderma gangrenosum pleural effusion Pyoderma gangrenosum is an unusual skin disease of unknown aetiology that[thorax.bmj.com]

  • IgG4-Related Retroperitoneal Fibrosis

    Pleural effusions can occur. On CT, findings are nonspecific, and usually appear as ground glass opacities.[rarediseasesjournal.com] hyperglobulinemia.[hematologyandoncology.net] "A Case of IgG4-Related Disease Presenting as Massive Pleural Effusion and Thrombophlebitis".[en.wikipedia.org]

  • Allergic Gastritis

    Sometimes eosinophilic pleural effusion is present. Eosinophilic gastroenteritis is a chronic, waxing and waning condition.[rarediseases.org] Elevated serum IgE, elevated levels of tumor necrosis factor (TNF-α) and interleukin-5 (IL-5) [ 17 ], polyclonal hyperglobulinemia, and good response to steroids are additional[clinicalmolecularallergy.biomedcentral.com] This fluid contains many eosinophils and can infiltrate the membrane of the lungs (pleural effusion). A history of allergy also appears to be common in this group.[healthofchildren.com]

  • Chronic Thyroiditis

    Pleural effusions can occur. On CT, findings are nonspecific, and usually appear as ground glass opacities.[rarediseasesjournal.com] Plasma protein electrophoresis showed polyclonal hyperglobulinemia, with normal immunofixation.[edmcasereports.com] hyperglobulinemia.[hematologyandoncology.net]

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