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273 Possible Causes for Pleural Effusion, Serositis, Splenomegaly

  • Systemic Lupus Erythematosus

    ESRp, serositis, and anti-dsDNA antibodies were related to disease activity regardless of infections.[ncbi.nlm.nih.gov] […] relapsing illness, with a variety of different presentations. [ 5 , 6 ] Symptoms and signs are often nonspecific - eg, fatigue (can be severe and debilitating), malaise, fever, splenomegaly[patient.info] Eosinophilic pleural effusion in elderly patients is most commonly due to malignancies and infections.[ncbi.nlm.nih.gov]

  • Juvenile Onset Stills Disease

    Appearance of rash, hepatosplenomegaly, serositis and generalized lymphadenopathy.[symptoma.com] (Y) 5 (83) 5 (71) 7 (39) Hepatomegaly OR splenomegaly (I) 5 (83) 6 (86) 10 (56) Only splenomegaly (N) 2 (33) 3 (43) 1 (6) Splenomegaly AND Hepatomegaly (N) 3 (50) 2 (29)[ped-rheum.biomedcentral.com] Visceral complications (pericarditis, pleural effusion or serous peritonitis with abdominal pain) may be present.[orpha.net]

  • Adult-Onset Still Disease

    Although less severe systemic manifestations, like serositis and pneumonitis, were observed, reversible liver involvement was common; the frequency of recurrent disease and[ncbi.nlm.nih.gov] […] clinically by high spiking fever, polyarthralgia/arthritis, a salmon-pink evanescent rash, predominantly neutrophilic leucocytosis, lymphadenopathy, liver dysfunction, and splenomegaly[ncbi.nlm.nih.gov] Anasarca developed with massive pleural effusion, ascites, and systemic edema, resulting in an increase of 47 kg in body weight.[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    Sclerosing extramedullary hematopoietic tumor (SEMHT) is a rare lesion and presented as retroperitoneal or serosal-based mass.[ncbi.nlm.nih.gov] We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[ncbi.nlm.nih.gov] The condition may result in GI tract hemorrhage, spinal cord compression, focal seizures, symptoms related to brain tumors, ascites, hematuria, pericardial effusion, pleural[emedicine.medscape.com]

  • Polyserositis

    Treatment of systemic lupus erythematosus-serositis. In: Current diagnosis and treatment: rheumatology. New York: McGraw-Hill; 2013.[jmedicalcasereports.biomedcentral.com] IM is a clinical triad of fever, sore throat, and lymphadenopathy.Headaches, myalgia, nausea, chills, arthralgia,jaundice and hepato‐splenomegaly can also occure.(4).Lab findings[shmabstracts.com] The latter preceded the appearance of pleural effusions.[ncbi.nlm.nih.gov]

  • Chronic Constrictive Pericarditis

    […] syndrome of heart(pericardial pseudocirrhosis of liver) - I31.1 Polyserositis due to pericarditis - I31.1 pericardial - I31.1 Pseudocirrhosis, liver, pericardial - I31.1 Serositis[icd10coded.com] In abdominal sonography, congestive hepatomegaly, mild splenomegaly, ascites, and evidence of portal hypertension were seen.[hindawi.com] […] liver) syndrome of heart I31.1 (pericardial pseudocirrhosis of liver) Polyserositis due to pericarditis I31.1 pericardial I31.1 Pseudocirrhosis, liver, pericardial I31.1 Serositis[icd10data.com]

  • Autoimmune Hemolytic Anemia

    Another commonly associated condition with wAIHA is lupus and thus findings of lupus should be assessed (facial rash, photosensitivity, serositis, oral ulcers, etc.).[clinicaladvisor.com] Examination demonstrated scleral icterus, splenomegaly, and anemia. By peripheral blood smear, the patient was diagnosed with Plasmodium ovale.[ncbi.nlm.nih.gov] She underwent computed tomography (CT) scan of the chest and abdomen, which demonstrates bilateral pleural effusion with multiple ill-defined patches of consolidation and[jahjournal.org]

  • Castleman Disease

    A 46-year-old man suffered from chronic fever, nephrotic syndrome, acute kidney injury, anemia, thrombocytopenia and serositis, as well as hypocomplementemia and negative[ncbi.nlm.nih.gov] Older age ( 40 years), splenomegaly, and hypoalbuminemia were risk factors for poorer MCD prognosis.[ncbi.nlm.nih.gov] All of UCD showed solitary mass in various sites and two of them were complicated by small pleural effusion.[ncbi.nlm.nih.gov]

  • Pulmonary Arterial Hypertension

    The presence of high fibrinogen, serositis, and thrombocytopenia were significantly higher in patients with PAH than in those without PAH (all P  0.05).[ncbi.nlm.nih.gov] The patient did not have any major symptoms attributed to CAEBV, such as fever, lymphadenopathy or splenomegaly when the PAH developed.[ncbi.nlm.nih.gov] After treatment with dasatinib he had multiple pleural effusions which were suspected to be caused by congestive heart failure.[ncbi.nlm.nih.gov]

  • Kaposi Sarcoma

    Kaposi sarcoma can cause concomitant serositis in kidney transplant patients and should be considered as a differential diagnosis.[ncbi.nlm.nih.gov] […] multicentric Castleman disease (MCD) is a rare, polyclonal lymphoproliferative disorder characterized by flares of inflammatory symptoms, edema, cytopenias, lymphadenopathy, and splenomegaly[ncbi.nlm.nih.gov] A CT scan showed diffuse pulmonary infiltrates with a 'tree-in-bud' appearance, striking splenomegaly and abdominal lymphadenopathy.[ncbi.nlm.nih.gov]

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