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53 Possible Causes for Polychromasia in Peripheral Blood Smear

  • Congenital Dyserythropoietic Anemia Type 1

    Anisopoikilocytosis with tear-drop forms, polychromasia, basophilic stippling in peripheral blood smear, erythroid hyperplasia with megaloblastoid changes, binucleated cells[unboundmedicine.com]

  • Congenital Dyserythropoietic Anemia

    Anisopoikilocytosis with tear-drop forms, polychromasia, basophilic stippling in peripheral blood smear, erythroid hyperplasia with megaloblastoid changes, binucleated cells[ncbi.nlm.nih.gov]

  • Paroxysmal Cold Hemoglobinuria

    Tests include complete blood count (CBC) and peripheral smear.[emedicine.com] The complete blood count usually shows normocytic anemia. Reticulocytosis may be subtle in the acute phase. Peripheral blood smear may show corresponding polychromasia.[en.wikipedia.org] The peripheral blood smear exhibits spherocytosis, polychromasia, nucleated red blood cells (RBCs), anisocytosis, poikilocytosis, and sometimes erythrophagocytosis by neutrophils[emedicine.com]

  • Acquired Thrombotic Thrombocytopenic Purpura

    Blood Smear (see Peripheral Blood Smear, [[Peripheral Blood Smear]]) Findings Polychromasia : due to reticulocytosis Schistocytes/Helmet Cells/Triangular Cells : RBC fragments[mdnxs.com] Number is affected by the duration of disease and quality of peripheral blood smear There is no threshold number of schistocytes below which TTP can be excluded Microspherocytes[mdnxs.com] Test, [[Direct Coombs Test]]) Negative : due to absence of immune hemolysis Indirect Coombs Test (Indirect Anti-Globulin Test) Negative : due to absence of immune hemolysis Peripheral[mdnxs.com]

  • Normocytic Normochromic Anemia

    Peripheral blood smear shows: Microcytosis and hypochromasia. There is anisocytosis, poikilocytosis. There are pencil cells (elliptical RBCs).[labpedia.net] There is polychromasia. Polychromasia in Hemolytic anemia Iron deficiency Anemia findings are: Low hemoglobin. Low Ferritin. Low serum iron. Low transferrin.[labpedia.net]

  • Cold Agglutinin Disease

    Reticulocytes and Spherocytes The results of the reticulocyte count are usually increased in patients with cold agglutinin disease, with polychromasia in the peripheral blood[web.archive.org] Other laboratory findings include reticulocytosis, positive DAT, auto agglutination and/or rouleaux on peripheral blood smear, polychromasia, and mild to moderate anisocytosis[keralamedicaljournal.com] smear.[web.archive.org]

  • Acquired Hemolytic Anemia

    blood smear : spherocytes, polychromasia Coombs test : positive Cold agglutinins titer C3 and C4 ; (due to complement activation) Prognosis: spontaneous remission within[amboss.com] blood smear : spherocytes, polychromasia Coombs test : positive Therapy Initial treatment of choice: glucocorticoids If glucocorticoids are unsuccessful Microangiopathic[amboss.com] […] non-Hodgkin lymphoma, chronic lymphocytic leukemia ) Clinical features Pallor, fatigue, weakness Cyanosis of the extremities ( acrocyanosis ) Diagnosis Signs of hemolysis Peripheral[amboss.com]

  • Zieve's Syndrome

    The peripheral blood smear revealed polychromasia and nucleated erythrocytes. The parents’ blood counts and smears were normal.[indianpediatrics.net] The patient's peripheral smear showed polychromasia, macrocytosis, tear drop cells, ovalocytes, spur cells, and schistocytes ( Figure 1 ).[ncbi.nlm.nih.gov] A stool occult blood test was negative. Upper endoscopy was normal with no varices.[ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    Peripheral blood smear showed polychromasia and spherocytosis. Haptoglobin level was 0.06 g/L ( N 0.16-2). Both hemoglobin electrophoresis and G6PD level were normal.[jahjournal.org] Red blood cell agglutination, polychromasia, target cells and spherocytes were seen on a peripheral smear.[doi.org]

  • Secondary Myelofibrosis

    The peripheral smear of patients with primary myelofibrosis includes red blood cells of variable shape (including tear drop cells) and size and variable degrees of polychromasia[mpncanada.com] Hepatomegaly is present in about 50% of patients. 24 Complete blood count (CBC) and peripheral blood smear A CBC is usually obtained to evaluate the hemoglobin level, white blood[mpncanada.com]

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