Create issue ticket

142 Possible Causes for Polycoria

  • Rieger Syndrome

    Typical ARS was defined as the presence of posterior embryotoxon with or without iris changes like stromal hypoplasia, corectopia, polycoria, or ectropion uvea with or without[ncbi.nlm.nih.gov] Polycoria is a feature of PITX2 mutations but not FOXC1. Polycoria; multiple pupillary openings FOXC1 and PITX2 proteins are both transcription factors.[slideserve.com] If photophobia is present in patients with corectopia and polycoria, contact lenses may be used to cover the holes in the iris.[orpha.net]

  • Iridocorneal Endothelial Syndrome

    Additional features of ICE included corneal endothelial guttata-like changes in 33 (46%), corneal edema in 7 (10%), iris pigment epithelial transillumination defects in 12 (17%), polycoria[ncbi.nlm.nih.gov] Common clinical features include corneal edema, secondary glaucoma, iris atrophy, and pupillary anomalies, ranging from distortion to polycoria.[ncbi.nlm.nih.gov] Iris changes in the form of polycoria were more common in our population compared to the other two populations (P Table 3.[ncbi.nlm.nih.gov]

  • Axenfeld-Rieger Syndrome Type 3

    If photophobia is present in patients with corectopia and polycoria, contact lenses may be used to cover the holes in the iris.[orpha.net] Ocular abnormalities mainly affect the iris: hypoplasia, corectopia or hole formation in the iris mimicking polycoria; cornea: prominent and anteriorly displaced Schwalbe's[orpha.net]

  • Chandler Syndrome

    […] patient may occasionally complain of monocular diplopia secondary to an exposed area of full thickness iris atrophy creating another entrance for light to enter the eye (polycoria[checkorphan.org] […] corneal endothelial cells migrate across the trabecular meshwork and onto the surface of the iris inducing anterior synechiae, and later ectropium uveae ( at 9 o'clock)and polycoria[atlasophthalmology.net] Polycoria, iris hole formation, and corectopia visible on a slit-lamp photo of a patient with Essential / Progressive Iris Atrophy.[eyewiki.aao.org]

  • Iris Atrophy

    Severe forms of iris atrophy can sometimes result in polycoria, affecting vision.[ncbi.nlm.nih.gov] […] may also involve both stroma and the iris pigment epithelium where there might be focal or generalized loss of both layers giving a moth-eaten appearance to the iris or polycoria[entokey.com] Polycoria, iris hole formation, and corectopia visible on a slit-lamp photo of a patient with Essential / Progressive Iris Atrophy.[eyewiki.aao.org]

  • Congenital Eye Anomaly

    If photophobia is present in patients with corectopia and polycoria, contact lenses may be used to cover the holes in the iris.[orpha.net] UVEAL TRACT  CORECTOPIA  ANIRIDIA  POLYCORIA  PERSISTENT PUPILLARY MEMBRANE  CONGENITAL COLOBOMA OF THE UVEAL TRACT 25.[slideshare.net] Polycoria - two or more pupils may exist in one iris.[patient.info]

  • Familial Porencephaly

    […] iris Underdeveloped iris 0007676 Microcornea Cornea of eye less than 10mm in diameter 0000482 Microphthalmia Abnormally small eyeball 0000568 Peripapillary atrophy 0500087 Polycoria[rarediseases.info.nih.gov]

  • Congenital Primary Aphakia

    […] microphakia: autosomal-recessive disease) · Michels (blepharophimosis, ptosis, epicanthus, cleft palate, deafness: autosomal-recessive disease) · Rieger (iridal ectopy or polycoria[fetalultrasound.com] […] may exist alone or in combination, including iris hypoplasia, enlarged or reduced corneal diameter, corneal vascularization and opacity, posterior embryotoxon, corectopia, polycoria[uniprot.org]

  • Retinal Degeneration-Nanophthalmos-Glaucoma Syndrome

    The clinical features of ASGD include iris hypoplasia, an enlarged or reduced corneal diameter, corneal vascularization and opacity, posterior embryotoxon, corectopia, polycoria[mendelian.co] […] without posterior embryotoxon or iris strands, corectopia (displacement of pupil) is present due to iridocorneal adhesions that are associated with membrane covering angle; polycoria[emedicine.medscape.com]

  • Peripheral Neuropathy

    […] may exist alone or in combination, including iris hypoplasia, enlarged or reduced corneal diameter, corneal vascularization and opacity, posterior embryotoxon, corectopia, polycoria[genecards.org]

Further symptoms