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32 Possible Causes for Portal and/or Bridging Fibrosis (Liver Biopsy

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  • Biliary Atresia

    Biliary atresia is a blockage in the tubes (ducts) that carry a liquid called bile from the liver to the gallbladder. Biliary atresia occurs when the bile ducts inside or outside the liver do not develop normally. The reason why this happens is unknown. The bile ducts help remove waste from the liver and carry salts[…][nlm.nih.gov]

  • Hepatitis

    biopsy indicating either portal or bridging fibrosis or at least moderate degrees of inflammation and necrosis.[web.archive.org] These persons include anti-HCV-positive patients with persistently elevated ALT levels, detectable HCV RNA, and a liver biopsy that indicates either portal or bridging fibrosis[web.archive.org] […] patients with chronic hepatitis C who are at greatest risk for progression to cirrhosis, as characterized by persistently elevated ALT levels; detectable HCV RNA; and a liver[web.archive.org]

  • Macronodular Cirrhosis

    biopsy showed diffuse macro vesicular steatosis with mixed inflammatory infiltrates and portal to portal bridging fibrosis, post mortem section from liver showed altered[omicsgroup.org] Definitions Fibrosis stage : stratified on liver biopsy to stages 0 to 4 using the METAVIR scoring system: (F0—no fibrosis, F1—portal fibrosis, F2—periportal fibrosis, F3—[ncbi.nlm.nih.gov] […] was of defect in fatty acid oxidation in a 3 year old male with complaints of developmental delay, the MRI of this case showed fatty change in neck muscles, ante-mortem liver[omicsgroup.org]

  • Cryptogenic Cirrhosis

    biopsy showed diffuse macro vesicular steatosis with mixed inflammatory infiltrates and portal to portal bridging fibrosis, post mortem section from liver showed altered[omicsonline.org] Liver biopsy demonstrated chronic hepatitis with mild to moderate activity and moderate to severe bridging fibrosis.[journals.lww.com] […] was of defect in fatty acid oxidation in a 3 year old male with complaints of developmental delay, the MRI of this case showed fatty change in neck muscles, ante-mortem liver[omicsonline.org]

  • Kimura Disease

    Liver biopsy revealed infiltration of lymphocytes and plasma cells in Glisson’s capsule and moderate-to-severe interface hepatitis with mild bridging fibrosis (Fig. 1 ), which[karger.com] Abdominal ultrasonography showed no intrahepatic mass, portal hypertension, or splenomegaly.[karger.com]

  • Liver Failure

    However, the presence of portal–portal bridging fibrosis on biopsy has been shown to be a poor prognostic sign.[nature.com] Histologic Staging of PBC The value of histologic staging in assessing prognosis in early-stage PBC is debatable, given the lack of uniformity of duct loss in the liver in[nature.com]

  • Drug-induced Idiosyncratic Hepatitis

    Viral serology was negative and liver biopsy revealed hepatitis with focal portal inflammatory bridging and fibrosis.[ajpb.com] Liver enzymes improved to 34/61 U/L (AST/ALT) and total bilirubin remained at 0.5 mg/dL after 5 months. 14 Female cases of DILI with atomoxetine where symptoms appeared later[ajpb.com]

  • IgG4-Related Hepatopathy

    Fibrosis staging was performed using Batts & Ludwig scoring system [24 ] as F0 (no fibrosis), F1 (increased portal fibrosis), F2 (periportal fibrosis), F3 (bridging fibrosis[tropicalgastro.com] In each liver biopsy inflammation was graded semiqantitatively as mild, moderate and severe.[tropicalgastro.com] In addition immunohistochemistry was performed using IgG4 antibody Zymed laboratories (10651USA) with dilution of 1:500 on all liver biopsies.[tropicalgastro.com]

  • Liver Disease

    However, the presence of portal–portal bridging fibrosis on biopsy has been shown to be a poor prognostic sign.[nature.com] Histologic Staging of PBC The value of histologic staging in assessing prognosis in early-stage PBC is debatable, given the lack of uniformity of duct loss in the liver in[nature.com]

  • Autoimmune Hepatitis

    However, the presence of portal–portal bridging fibrosis on biopsy has been shown to be a poor prognostic sign.[dx.doi.org] Histologic Staging of PBC The value of histologic staging in assessing prognosis in early-stage PBC is debatable, given the lack of uniformity of duct loss in the liver in[dx.doi.org]

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