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167 Possible Causes for Portal Tract Fibrosis

  • Congenital Hepatic Fibrosis

    Portal tract fibrosis with biliary enlargement and proliferation occurs also with tubulointerstitial kidney diseases.[humpath.com] BACKGROUND: Congenital hepatic fibrosis is a rare disease characterized by portal tract fibrosis and biliary duct ectasia.[ncbi.nlm.nih.gov] A buildup of scar tissue (fibrosis) in the portal tracts also occurs in this disorder.[ghr.nlm.nih.gov]

  • Hepatoportal Sclerosis

    The histopatological analysis of liver samples from both patients showed portal tracts enlarged by fibrosis with disappearance or reduction in the diameter of the portal vein[ncbi.nlm.nih.gov] […] veins Microscopic • Abnormal hepatic architecture with lack of consistent relationship between portal tracts and central veins • Portal fibrosis • Narrowing or obliteration[basicmedicalkey.com] In many portal tracts, portal veins branches were replaced by aberrant thin-walled fendiforme vessels.[ncbi.nlm.nih.gov]

  • Aagenaes Syndrome

    This could develop into hepatic cirrhosis & giant cell hepatitis (which could occur with portal tract fibrosis).[signssymptoms.org] […] of the portal tracts Cholestasis-edema syndrome, Norwegian type (disorder) Cholestasis-edema syndrome, Norwegian type Lymphedema-Cholestasis Syndrome Chls LCS1 Cholestasis[wikidata.org] […] of the portal tracts. [1] [2] The genetic cause is unknown, but it is autosomal recessively inherited and the gene is located to chromosome 15q 1,2.[en.wikipedia.org]

  • Congenital Liver Cirrhosis

    Portal tract fibrosis with biliary enlargement and proliferation occurs also with tubulointerstitial kidney diseases.[humpath.com] A buildup of scar tissue (fibrosis) in the portal tracts also occurs in this disorder.[ghr.nlm.nih.gov] […] veins, progressive fibrosis of portal tracts ( GeneReviews: Congenital Hepatic Fibrosis Overview [Accessed 25 October 2017] ) Anastomosing biliary channels in irregular,[pathologyoutlines.com]

  • IgG4-Related Hepatopathy

    The liver mass was resected and histological examination revealed that infiltration of inflammatory cells, lymphoid follicles, and fibrosis were seen in portal tract.[kyushu-u.pure.elsevier.com] Plasma cell infiltration was observed in the portal tracts and parenchyma, though fibrosis was not significant.[ncbi.nlm.nih.gov] The extracted gall bladder showed lymphoplasmacytic infiltration and subserosal fibrosis.[ncbi.nlm.nih.gov]

  • Cholangitis

    tracts or piecemeal necrosis Piecemeal necrosis or fibrosis without bridging Bridging necrosis or fibrosis Cirrhosis Laboratory Elevated alkaline phosphatase, IgM, IgG Variable[pathologyoutlines.com] […] the portal tracts. (1) Most patients are over 45 years of age, with a 2:1 male predominance.[sonoworld.com] […] of the intrahepatic and/or extrahepatic bile ducts and a lymphocytic portal tract inflammation leading to cholestasis, cholangitis, and cirrhosis.[omicsonline.org]

  • Cholestatic Jaundice

    It has a diagnostic accuracy of 90%.[ 27 ] Itreveals portal tract oedema, fibrosis, inflammation, intracellularand canalicular cholestasis, and proliferation of bile ductules[tropicalgastro.com]

  • Liver Cirrhosis

    (ideally 2cm or longer, and containing 11 or more complete portal tracts) may influence the fibrosis score [ 28 ].[ncbi.nlm.nih.gov] Intermediate stages 1 and 3 correspond to fibrous expansion of portal tracts (score 1) and bridging fibrosis (score 3), respectively.[ncbi.nlm.nih.gov] […] hypertension.[38] No fibrosis, but mild zone 3 steatosis, in which collagen fibres (pink–red, arrow) are confined to portal tracts (P) (Van Gieson's stain)[39] Histopathology[en.wikipedia.org]

  • Cholestasis

    tract fibrosis Microscopic (histologic) images Images hosted on other servers : Back to top[pathologyoutlines.com] Over time, areas around portal tracts undergo progressive fibrosis (i.e. Periportal Fibrosis) which septates the hepatic parenchyma.[pathwaymedicine.org] […] degeneration of hepatocytes, bile duct proliferation (proliferation of epithelial cells and looping / reduplication of ducts), concretions, periportal neutrophils Late: bile lakes, portal[pathologyoutlines.com]

  • Hemochromatosis

    Liver Hemosiderin granules are first observed in hepatocytes near portal tracts but with increasing overload are observed diffusely throughout the organ.[pathwaymedicine.org] Because iron activates Ito Cells, significant hepatic fibrosis ensues, which can progress to frank cirrhosis and eventually hepatic failure.[pathwaymedicine.org]

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