Postprandial Hyperglycemias: Causes & Reasons

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Possible Causes for Postprandial Hyperglycemias

Donohue Syndrome

Diagnosis is made on clinical (Fig. 1), biochemical (fasting hypoglycemia, postprandial hyperglycemia, and extreme hyperinsulinemia), and genetic grounds. [academic.oup.com]

Glucose homeostasis is affected with hyperinsulinemia, fasting hypoglycemia, and postprandial hyperglycemia. [ncbi.nlm.nih.gov]

Extreme resistance to insulin leads to severe hyperinsulinemia, postprandial hyperglycemia, and a characteristic fasting hypoglycemia. [cags.org.ae]

Maturity-Onset Diabetes of the Young Type 2

hyperglycemia from birth, lack of progression, and absence of insulin requirement and vascular complications. [care.diabetesjournals.org]

[…] characteristics reported for the RW pedigree (MODY1) and families with MODY3 are subjects with glucokinase mutations (GCK-MODY, MODY2) who have mild fasting (110–140 mg/dL) and postprandial [care.diabetesjournals.org]

Insulin-Resistance Syndrome Type B

A case of type B insulin resistance syndrome with postprandial hyperglycemia successfully treated with liraglutide. [kyushu-u.pure.elsevier.com]

Hyperinsulinemia due to impaired insulin clearance associated with fasting hypoglycemia and postprandial hyperglycemia: an analysis of a patient with antiinsulin receptor [link.springer.com]

Rare and severe autosomal recessive presenting in the first decade of life Donohue syndrome Rabson Mendenhall syndrome (RMS) fasting hypoglycemia, Postprandial hyperglycemia [slideshare.net]

Glycogen Storage Disease Type 0

The diagnosis of GSD0 should be considered in a child with ketotic fasting hypoglycemia with postprandial hyperglycemia but without hepatomegaly. [ncbi.nlm.nih.gov]

hyperglycemia and her parents. [ncbi.nlm.nih.gov]

Although feeding relieves symptoms, it often results in postprandial hyperglycemia and hyperlactatemia. [ncbi.nlm.nih.gov]

Hyperglycemia

[…] vysoká glykemie [cze0042318] postprandiální hyperglykemie [cze0042319] postprandiální hyperglykémie [cze0042320] See Hyperglycemia, Postprandial [T713587] Postprandial Hyperglycemia [medvik.cz]

This often results in postprandial hyperglycemia. Steroid-induced hyperglycemia is related to the dose of steroid, but not the type of steroid. [healio.com]

hyperglycemia). [clinical.diabetesjournals.org]

Perioophoritis

hyperglycemia食後過血糖 postprandial hyperglycemia食後高血糖 postprandial hyperlipemia食後高脂血症 postprandial hyperlipidemia食後高脂血症 postprandial hypoglycemia食後低血糖 postprandial hypotension [jds.or.jp]

[…] portal vein insulin門脈血インスリン portal vein insulin infusion門脈インスリン注入 post-exercise late-onset hypoglycemia運動後遅発性低血糖 post-treatment neuropathy治療後神経障害 postabsorptive state吸収後状態 postprandial [jds.or.jp]

Rabson-Mendenhall Syndrome

hyperglycemia, extreme hyperinsulinemia, protracted course, and eventual development of ketoacidosis. [ncbi.nlm.nih.gov]

It is characterized by severe insulin resistance leading to postprandial hyperglycemia and fasting hypoglycemia. [cags.org.ae]

Rabson-Mendenhall syndrome is a rare genetic disorder characterized by severe insulin resistance, extreme hyperinsulinemia, postprandial hyperglycemia, growth retardation, [ncbi.nlm.nih.gov]

Nateglinide

Abstract Nateglinide is a novel rapid- and short-acting insulin secretagogue that ameliorates postprandial hyperglycemia by improving insulin secretory dynamics to a near [ncbi.nlm.nih.gov]

Postprandial hyperglycemia, expressed as mean blood glucose over a time period of 2 h after a meal, declined significantly after all three daily meals. [ncbi.nlm.nih.gov]

Nateglinide may ameliorate hypoadiponectinemia as well as postprandial hyperglycemia in patients with type 2 diabetes mellitus. [Indexed for MEDLINE] Free full text [ncbi.nlm.nih.gov]

Miglitol

Postprandial hyperglycemia is one of the important factors contributing to an increase in the circulating pro-inflammatory cytokine levels. [ncbi.nlm.nih.gov]

Repeated postprandial hyperglycemia may play an important role in the development of atherosclerosis by suppressing vascular endothelial function. [ncbi.nlm.nih.gov]

OBJECTIVE: In this study, we examined whether inhibition of postprandial hyperglycemia by combination therapy with two drugs for reducing postprandial hyperglycemia, i.e., [ncbi.nlm.nih.gov]

Liver Glycogen Synthase Deficiency

Although feeding relieves symptoms, it often results in postprandial hyperglycemia and hyperlactatemia. [experts.umn.edu]

Although feeding relieves symptoms, it often results in postprandial hyperglycemia and hyperlactatemia. {ECO:0000269 PubMed:9691087}. [genecards.org]

Although feeding relieves symptoms, it results in postprandial hyperglycemia and hyperlacticacidemia. [emedicine.medscape.com]

Insulin-Resistance Syndrome Type A

A case of type B insulin resistance syndrome with postprandial hyperglycemia successfully treated with liraglutide. [kyushu-u.pure.elsevier.com]

Rare and severe autosomal recessive presenting in the first decade of life Donohue syndrome Rabson Mendenhall syndrome (RMS) fasting hypoglycemia, Postprandial hyperglycemia [slideshare.net]

Therefore, the amount of glucose produced by the liver is not inversely proportional to the amount of glucose influx, and this results in postprandial hyperglycemia. [podiatrytoday.com]

Paroxysmal Atrial Fibrillation

A 73-year-old Japanese woman with postprandial hyperglycemia suffered from drug-refractory paroxysmal atrial fibrillation. [ncbi.nlm.nih.gov]

We describe a very unique case with postprandial hyperglycemia and obesity associated with drug-refractory paroxysmal atrial fibrillation. [ncbi.nlm.nih.gov]

Diet and exercise should be considered as the initial therapy in patients with paroxysmal atrial fibrillation who also have postprandial hyperglycemia. [ncbi.nlm.nih.gov]

Orotic Aciduria Type 2

hyperglycemia Subcortical cerebral atrophy Cholestatic liver disease Recurrent hypoglycemia Diastasis recti Microcytic anemia Shallow orbits Steatorrhea Hyperglycemia Portal [mendelian.co]

Elevated hepatic transaminase Hyperkeratosis Polydactyly Hyperhidrosis Increased urinary sedoheptulose Abnormality of globe location Neonatal asphyxia Abnormal CNS myelination Postprandial [mendelian.co]

GCGR-Related Hyperglucagonemia

Decrease in the contribution of extracellular pathway to hepatic glycogen synthesis; Role of abnormal hepatic and muscle glucose metabolism on postprandial hyperglycemia; [connection.ebscohost.com]

Dumping Syndrome

Meal tolerance testing 3 months after oral sitagliptin, compared to before starting treatment, showed reductions in both early postprandial hyperglycemia and insulin hypersecretion [ncbi.nlm.nih.gov]

Octreotide prevented the symptoms of early dumping syndrome, especially postprandial tachycardia, but caused postprandial hyperglycemia. [ncbi.nlm.nih.gov]

Acarbose attenuated both postprandial glucose hyperglycemia and reactive hypoglycemia, which subsequently led to a significant reduction in dumping symptoms. [ncbi.nlm.nih.gov]

Insulin Antibody

Production of these "IAS-like" insulin antibodies causes marked glycemic fluctuations with postprandial hyperglycemia and fasting hypoglycemia. [ncbi.nlm.nih.gov]

[…] blood glucose食後血糖［値］ postprandial hyperglycemia食後高血糖、食後過血糖 postprandial hypoglycemia食後低血糖 postprandial lipemia食後高脂血症 post-treatment neuropathy治療後神経障害 primary prevention一次予防 [tokyo-med.ac.jp]

Therefore, he took oral prednisolone 30 mg per day for his IAS-like situation, and a good response was observed without the deterioration of hyperglycemia by frequent blood [edmcasereports.com]

Hypothalamic Adipsic Hypernatraemia Syndrome

Liver Phosphorylase Kinase Deficiency

Patients with type 0 GSD (hepatic glycogen synthase deficiency) present with fasting ketotic hypoglycemia that alternates with postprandial hyperglycemia and hyperlactatemia [clinicaladvisor.com]

The desease is characterized by hepatorenal glycogen accumulation, fasting hypoglycemia as well as postprandial hyperglycemia and hypergalactosemia, proximal renal tubular [wjgnet.com]

Disorder Enzyme Deficiency Cardinal Clinical Features Distinctive Features Type 0 Glycogen synthase Fasting hypoglycemia and ketosis No hepatomegaly; postprandial hyperglycemia [clinicaladvisor.com]

Chromosome 16q22 Deletion Syndrome

hyperglycemia Absence of subcutaneous fat Female pseudohermaphroditism Hyperparathyroidism Irregular vertebral endplates Progressive gait ataxia Memory impairment Abnormality [mendelian.co]

[…] reflux Torus palatinus Abnormality of the abdominal wall Motor tics Myopia Feeding difficulties Asymmetry of the breasts Prominent nipples Adipose tissue loss Elfin facies Postprandial [mendelian.co]

Transient Infantile Hypertriglyceridemia and Hepatosteatosis

The earliest biochemical abnormality tends to be postprandial hyperglycemia. The majority of patients require insulin treatment. [diabetesincontrol.com]

Hypokalemic Periodic Paralysis

hyperglycemia 0011998 5%-29% of people have these symptoms Late-onset proximal muscle weakness 0003694 Myopathy Muscle tissue disease 0003198 1%-4% of people have these symptoms [rarediseases.info.nih.gov]

0003752 Increased intramyocellular lipid droplets 0012240 Mildly elevated creatine kinase 0008180 30%-79% of people have these symptoms Exercise-induced muscle fatigue 0009020 Postprandial [rarediseases.info.nih.gov]

Fanconi-Bickel Syndrome

Patients with type 0 GSD (hepatic glycogen synthase deficiency) present with fasting ketotic hypoglycemia that alternates with postprandial hyperglycemia and hyperlactatemia [clinicaladvisor.com]

Treatment consists of a diet high in protein to provide a substrate for gluconeogenesis and with low glycemic index complex carbohydrates to minimize postprandial hyperglycemia [clinicaladvisor.com]

Hyperalaninemia

A third patient was consulted for ketotic hypoglycemia and postprandial hyperglycemia at the 5 years of age. [degruyter.com]

Glucose monitoring in both patients revealed daily fluctuations from fasting hypoglycemia to postprandial hyperglycemia and lactic acidemia. [degruyter.com]

Methylprednisolone

Author information 1 Institute of Fundamental Medicine and Biology, Kazan (Volga Region) Federal University, 18 Kremlyovskaya St., 420008 Kazan, Russia. 2 School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton BN2 4GJ, UK. 3 Institute of Fundamental Medicine and Biology, Kazan (Volga Region)[…] [ncbi.nlm.nih.gov]

Sucrose

reactive hypoglycemia, postprandial hypotension [33], epilepsy, fructose malabsorption, small intestinal bacterial overgrowth (SIBO), irritable bowel syndrome (IBS). [nutrientsreview.com]

] GLUT1 deficiency syndrome [35] Glucose-galactose malabsorption [34] Individuals with the following conditions may also benefit from avoiding sucrose: diabetes 1 and 2, hyperglycemia [nutrientsreview.com]

Hypoglycemia

hyperglycemia. [ncbi.nlm.nih.gov]

3. insulin resistance: (i.e.early type-II diabetes with postprandial hyperglycemia, >180 mg/dl) after carbohydrates (30--90 min) and late elevated insulin response / rightward [web.archive.org]

BG spikes after a low In about 20% of cases, rebound hyperglycemia (or blood sugar spikes) occur after a a low. [beyondtype1.org]

Muscle Phosphorylase Kinase Deficiency

Patients with type 0 GSD (hepatic glycogen synthase deficiency) present with fasting ketotic hypoglycemia that alternates with postprandial hyperglycemia and hyperlactatemia [clinicaladvisor.com]

Diabetes Mellitus

In type 2 diabetic patients, such diets may cause marked postprandial hyperglycemia. [academic.oup.com]

They primarily target postprandial hyperglycemia but do it without causing hypoglycemia. [clevelandclinicmeded.com]

A diet composed of 50–60% carbohydrates often will result in excessive weight gain and postprandial hyperglycemia. [journals.lww.com]

Glycogen Storage Disease Type 9

Patients with type 0 GSD (hepatic glycogen synthase deficiency) present with fasting ketotic hypoglycemia that alternates with postprandial hyperglycemia and hyperlactatemia [clinicaladvisor.com]

The desease is characterized by hepatorenal glycogen accumulation, fasting hypoglycemia as well as postprandial hyperglycemia and hypergalactosemia, proximal renal tubular [wjgnet.com]

Glycogen Storage Disease Type 6

Patients with type 0 GSD (hepatic glycogen synthase deficiency) present with fasting ketotic hypoglycemia that alternates with postprandial hyperglycemia and hyperlactatemia [clinicaladvisor.com]