Precocious Female Puberty: Causes & Reasons

Possible Causes for Precocious Female Puberty

With respect to female central precocious puberty, approximately 80%-90% have no underlying pathology. [rxlist.com]

Similar to the treatment of central precocious puberty, the prognosis is related to the precise cause of the child's disease. [medicinenet.com]

RESULTS: This young female patient had clinical and imaging findings suggestive of idiopathic central precocious puberty. [ncbi.nlm.nih.gov]

Adrenocortical Carcinoma

[…] because of excess testosterone production) feminization (acquisition of female traits in a male because of excess estrogen production) precocious puberty (puberty occurring [endocrineweb.com]

Prepubertal boys with male hormone excess present with precocious (early) puberty. Feminizing tumors in women may cause breast tenderness and excessive vaginal bleeding. [csrf.net]

[…] below. hypercortisolism ( Cushing's syndrome ) (excess cortisol produced) adrenogenital syndrome (excess sex steroids produced) virilization (acquisition of male traits in a female [endocrineweb.com]

Osteitis Fibrosa Disseminata

Puberty in Females}, author={Fuller Albright and Allan M. [semanticscholar.org]

Sign in Original ArticleFree PreviewArchive Syndrome Characterized by Osteitis Fibrosa Disseminata, Areas of Pigmentation and Endocrine Dysfunction, with Precocious Puberty [nejm.org]

puberty in females: Report of five cases. [scirp.org]

McCune-Albright Syndrome

She was diagnosed with gonadotropin independent precocious puberty with eventual progression to gonadotropin dependent precocious puberty which was successfully treated with [ncbi.nlm.nih.gov]

A 5 y/o female presented with classic MAS (café-au-lait spots, polyostotic fibrous dysplasia, and precocious puberty). [nature.com]

Four females with precocious puberty had final heights that were not different from the mean for normal females; they eventually developed regular menses, and two had children [doi.org]

Familial Testotoxicosis

Familial male-limited precocious puberty Other names Familial sexual precocity Male-limited precocious puberty has an autosomal dominant pattern of inheritance. [en.wikipedia.org]

While in general precocious puberty is much more common in females than males, hereditary forms are more common in males. [healthcentral.com]

Females with mutations associated with familial male-limited precocious puberty appear to be unaffected. [medlineplus.gov]

Precocious Puberty

(male and female) Causes and management of precocious puberty and delayed puberty (female only ... examination of the child Vaginal bleeding Vulvovaginitis Labial adhesions [rcog.org.uk]

While in general precocious puberty is much more common in females than males, hereditary forms are more common in males. [healthcentral.com]

Males 14-16 Females 11-14 3. PRECOCIOUS PUBERTY The process of puberty before 7-8 yrs in females and 9 yrs of age in Males.. [slideshare.net]

Aromatase excess syndrome

[…] soon after adrenarche) (2) prepubertal or peripubertal gynecomastia Features in females: (1) precocious puberty (2) macromastia Laboratory findings: (1) elevated serum levels [meducator3.net]

Female patients may have isosexual precocious puberty or not have any manifestations at all. [orpha.net]

Female patients may have isosexual precocious puberty or not have any manifestations at all.Visit the Orphanet disease page for more resources. [malacards.org]

Glutamyl Ribose-5-Phosphate Storage Disease

Puberty GNT155 Genetic Precocious Puberty in Female GNT154 Genetic Primary Hypomagnesemia with Hypocalciuria GNT181 Genetic Primary Hypomagnesemia with Normocalciuria GNT180 [malacards.org]

Anomaly of the Skin GNT094 Genetic Polycythemia GNT106 Genetic Polyendocrinopathy GNT057 Genetic Porokeratosis GNT096 Genetic Posterior Fossa Malformation GNT122 Genetic Precocious [malacards.org]

Central Precocious Puberty Type 1

puberty in female rats.Neurosci-Lett. 2001 Jan 5; 297(1): 45-8Arisaka,-O; Hoshi,-M; Kanazawa,-S; Numata,-M; Nakajima,-D; Kanno,-S; Negishi,-M; Nishikura,-K; Nitta,-A; Imataka [malattierare.regione.veneto.it]

[…] gamma-aminobutyric acid-ergic neurotransmission as a putative mechanism of radiation induced activation of the gonadotropin releasing-hormone-pulse generator leading to precocious [malattierare.regione.veneto.it]

female 238320 Precocious puberty, male 176410 LHX3 9q34.3 Pituitary hormone deficiency, combined, 3 221750 LIFR 5p13.1 Stuve-Wiedemann syndrome/Schwartz-Jampel type 2 syndrome [institutobernabeu.com]

puberty 176410 Leydig cell hypoplasia with hypergonadotropic hypogonadism 238320 Leydig cell hypoplasia with pseudohermaphroditism 238320 Luteinizing hormone resistance, [institutobernabeu.com]

613471 Greenberg skeletal dysplasia 215140 Pelger-Huet anomaly 169400 LEPRE1 1p34.2 Osteogenesis imperfecta, type VIII 610915 LHCGR 2p16.3 Leydig cell adenoma, somatic, with precocious [institutobernabeu.com]

[…] infants, pseudo-precocious puberty in both genders, hirsutism in late-onset forms Virilised genitalia in female infants, pseudo-precocious puberty in both genders, hirsutism [datospdf.com]

[…] liase deficiency CYP17A1 (10q24.3) Cytochrome P450 oxidoreductase deficiency POR (7q11.2) Lipoid congenital adrenal hyperplasia STAR (8p11.2) Virilised external genitalia in female [datospdf.com]

Central Precocious Puberty Type 2

With respect to female central precocious puberty, approximately 80%-90% have no underlying pathology. [medicinenet.com]

puberty: epidemiology, etiology, diagnosis and treatment Enlaces Texto completo ( pdf ) Resumen Abstract Central precocious puberty (CPP) is a rare disease with female predominance [dialnet.unirioja.es]

Age If precocious puberty in females (mostly central) is defined as the early onset of breast development, then the data of Herman-Giddens et al can be used to estimate frequency [emedicine.medscape.com]

15q11-q13 Duplication Syndrome

puberty and, in females, menstrual irregularities; minor genital abnormalities in males such as undescended testes (cryptorchidism); overeating; and excessive weight gain [malacards.org]

[…] include a reduced ability to feel pain; a spine that curves to the side (scoliosis); recurrent respiratory infections in childhood; a skin condition called eczema; early (precocious [malacards.org]

Polyostotic Fibrous Dysplasia

Four females with precocious puberty had final heights that were not different from the mean for normal females; they eventually developed regular menses, and two had children [doi.org]

Smith: Syndrome characterized by osteitis fibrosa disseminata, areas of pigmentation and endocrine dysfunction, with precocious puberty in females. Report of five cases. [whonamedit.com]

Precocious puberty is more common in females than males with more than 50% of females experiencing precocious puberty. [rarediseases.org]

Mucopolysaccharidosis Type 3C

Excluded from analysis were two MPS IIIA patients (1 male, 1 female) with central precocious puberty. [ojrd.biomedcentral.com]

The incidence of precocious puberty was 1.1% (1 female, 1 male) in the present study, and therefore lower than reported in the literature. [ojrd.biomedcentral.com]

Two patients (1 female, 1 male) developed a precocious puberty. Their data were only included up to their 6th birthday, before the start of puberty and medication. [ojrd.biomedcentral.com]

Ovarian Hyperfunction

[…] and following adolescence, after at least 1 year wash out of any treatment for precocious puberty. [ncbi.nlm.nih.gov]

Genitori Journal of Pediatric Endocrinology & Metabolism (JPEM) 2006 Volume 19, Suppl. 2 595-604 en Gsα-related precocious puberty in Females: Focus on treatement T.S. [eamas.net]

Syndrome characterized by osteitis fibrosa disseminata, areas of pigmentation and endocrine dysfunction, with precocious puberty in females: report of five cases. N. [link.springer.com]

Joubert Syndrome Type 18

puberty 176410 Leydig cell hypoplasia with hypergonadotropic hypogonadism 238320 Leydig cell hypoplasia with pseudohermaphroditism 238320 Luteinizing hormone resistance, [institutobernabeu.com]

Congenital Adrenal Hyperplasia

and/or precocious puberty (in both males and females). [amboss.com]

Mild 21-hydroxylase deficiency may present with females having precocious puberty and accelerated growth (simple virilization) or hirsutism, oligomenorrhea, and infertility [pedemmorsels.com]

both males and females may also experience precocious puberty, short stature, hirsutism, acne and fertility problems. [neurocrine.com]

Acquired Adrenogenital Syndrome

In acquired adrenogenital syndrome there is appearance of masculine secondary sex characters in the female, and precocious puberty in the male. Treatment. [medical-dictionary.thefreedictionary.com]

Adrenogenital Syndrome

Fibrous Dysplasia

• Precocious puberty in female patients may be associated with the polyostotic form (McCune-Albright’s syndrome) • May be associated with soft tissue myxomas (Mazabraud’ [tumorsurgery.org]

Central precocious puberty (females & males) 6 Leuprolide combined w/medications listed above for precocious puberty Persistent ovarian cysts Prophylactic surgical intervention [ncbi.nlm.nih.gov]

puberty in females. [oap-journals.org]

Polyembryoma

puberty); or irregularities in a female's menstruation. [diseaseinfosearch.org]

[…] at an unusually young age (known as precocious puberty ); or irregularities in a female's menstruation. [rarediseases.info.nih.gov]

Symptoms of a polyembryoma may include an unusual bump or mass in the abdomen which can cause pain in some individuals; puberty at an unusually young age (known as precocious [diseaseinfosearch.org]

Laugier-Hunziker Syndrome

The disease is also accompanied by precocious puberty in females and fibrous dysplasia.11 Nayak RS, Kotrashetti VS, Hosmani JV. Laugier-Hunziker syndrome. [scielo.br]

puberty in females). [edm.bioscientifica.com]

The disease is also accompanied by precocious puberty in females and fibrous dysplasia. [jomfp.in]

Mazabraud Syndrome

Precocious puberty is more common in females than males with more than 50% of females experiencing precocious puberty. [rarediseases.org]

Syndrome characterized by osteitis fibrosa disseminata, areas of pigmentation and endocrine dysfunction, with precocious puberty in females: report of five cases. [dysplasie-fibreuse-des-os.info]

[…] menstruation Type 1 Excludes Albright (-McCune) (-Sternberg) syndrome ( Q78.1 ) central precocious puberty ( E22.8 ) congenital adrenal hyperplasia ( E25.0 ) female heterosexual [icd10data.com]

Lichtenstein Syndrome

Smith: Syndrome characterized by osteitis fibrosa disseminata, areas of pigmentation and endocrine dysfunction, with precocious puberty in females: report of five cases. [whonamedit.com]

The McCune-Albright syndrome includes polyostotic fibrous dysplasia, café-au-lait melanotic macules, and endocrine abnormalities, such as precocious puberty in females. [dentalcare.com]

Delayed Male Puberty

Precocious Puberty Definition Precocious puberty is the development of secondary sexual characteristics before the age of 8 in females and 9 in males. [lecturio.com]

(E25.0) 여성의 이성 조숙의 가성사춘기(female heterosexual precocious pseudopuberty)(E25.-) 남성의 동성 조숙의 가성사춘기(male isosexual precocious pseudopuberty)(E25.-) E30.8 사춘기의 기타 장애(Other disorders [dic.impact.pe.kr]

여성 이성 조발 거짓사춘기(E25.0)(Female heterosexual precocious pseudopuberty) - 제외 : 남성 동성 조발 거짓사춘기(E25-)(Male isosexual precocious pseudopuberty) E30.8 기타 사춘기장애(Other disorders [koicd.kr]

Joubert Syndrome Type 10

puberty 176410 Leydig cell hypoplasia with hypergonadotropic hypogonadism 238320 Leydig cell hypoplasia with pseudohermaphroditism 238320 Luteinizing hormone resistance, [institutobernabeu.com]

46,XX Testicular Disorder of Sex Development

238320 LHCGR 169.9 0.97 0.93 Luteinizing hormone resistance, female, 238320 LHCGR 169.9 0.97 0.93 Precocious puberty, male, 176410 MAMLD1 139.3 0.99 0.98 Hypospadias 2 X-linked [qgenomics.com]

puberty, 176410 LHCGR 169.9 0.97 0.93 Leydig cell hypoplasia with hypergonadotropic hypogonadism, 238320 LHCGR 169.9 0.97 0.93 Leydig cell hypoplasia with pseudohermaphroditism [qgenomics.com]

[…] male, with gynecomastia, 264300 HSD3B2 178.2 1 1 3-beta-hydroxysteroid dehydrogenase, type II, deficiency, 201810 LHCGR 169.9 0.97 0.93 Leydig cell adenoma, somatic, with precocious [qgenomics.com]

Craniofacial Dysplasia

puberty in females 3 4 ; and a craniofacial form (CFD) in which only bones of the craniofacial complex are affected. 5 The majority of patients with CFD present in their [jmg.bmj.com]

O., Smith, P. ( 1937 ) Syndrome characterized by osteitis fibrosa disseminata, areas of igmentation and endocrine dysfunction with precocious puberty in females. [cambridge.org]

Syndrome characterized by osteitis fibrosa disseminata, areas of pigmentation and endocrine dysfunction, with precocious puberty in females: Report of five cases. [surgicalneurologyint.com]

Hypothalamic Hamartoma

A 11 month old female child with bleeding per vagina. Precocious puberty as per endocrinologist, advised MRI Brain for Pituitary. [neuroradiologycases.com]

The male-female ratio of hamartomas with precocious puberty derived from these data is 2:1. [jamanetwork.com]

The patient was an 11-year-old female with a history of central hypothyroidism, precocious puberty, and localization-related epilepsy thought to be secondary to an HH. [ncbi.nlm.nih.gov]