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239 Possible Causes for Premature Osteoarthritis

  • Osteoarthritis

    KEYWORDS: COL2A1 Arg75Cys mutation; COL2A1 mutation; Familial juvenile osteoarthritis; Hip joint pain; Premature osteoarthritis; Type II collagenopathies[ncbi.nlm.nih.gov] Deficient autophagy induces premature senescence in aging and osteoarthritis. Osteoarthr.[ncbi.nlm.nih.gov]

  • Obesity

    These conditions can cause or contribute to premature death and substantial disability.[news-medical.net] It has recently been estimated that about 1 in 10 premature deaths among Canadian adults 20–64 years of age is directly attributable to overweight and obesity.[cmaj.ca] […] pressure ) Dyslipidemia (for example, high total cholesterol or high levels of triglycerides) Stroke Liver and Gallbladder disease Sleep apnoea and respiratory problems Osteoarthritis[news-medical.net]

  • Osteoarthritis of the Knee

    A woman presented with premature knee osteoarthritis associated with marked femoral cartilage hypertrophy.[ncbi.nlm.nih.gov] , or applied to clinical models besides osteoarthritis of the knee.[journals.plos.org] As the mechanism(s) of action of massage are not fully elucidated, it is premature to predict dose-responses for higher or lower doses than the doses utilized in this trial[journals.plos.org]

  • Spondyloepiphyseal Dysplasia Tarda

    Clinical features include onset in childhood, a disproportionately short stature and premature osteoarthritis.[ncbi.nlm.nih.gov] Appropriate lifestyle decisions and, eventually, perhaps, specific SEDL therapies may ameliorate the prognosis of premature osteoarthritis and the need for hip arthroplasty[ncbi.nlm.nih.gov] osteoarthritis , especially in the hip joints.[monarchinitiative.org]

  • Hemochromatosis

    These include: enlarged liver, unexplained persistent elevation of liver enzymes, cirrhosis arthritis (including premature osteoarthritis and classic arthropathy of thumb,[www2.gov.bc.ca] A simple iron panel should be performed on anyone with a family history of any of the following: • a premature death by heart attack or liver cancer • diabetes mellitus •[irondisorders.org] If untreated, hemochromatosis can cause serious disease and premature death.[www2.gov.bc.ca]

  • Stickler Syndrome

    osteoarthritis).[ncbi.nlm.nih.gov] Systemic signs include premature osteoarthritis and hearing loss, as well as numerous skeletal and facial malformations, such as maxillofacial hypoplasia and cleft palate.[ncbi.nlm.nih.gov] It has a highly variable phenotype that can include midline clefting, hearing loss, premature osteoarthritis, congenital high myopia and blindness through retinal detachment[ncbi.nlm.nih.gov]

  • Legg-Calve-Perthes Disease

    Legg-Calvé-Perthes disease is a juvenile form of idiopathic osteonecrosis of the femoral head that can lead to permanent femoral head deformity and premature osteoarthritis[ncbi.nlm.nih.gov] The literature documents numerous private mutations in COL2A1 associated with diverse clinical phenotypes including bilateral hip dysplasia and premature osteoarthritis.[ncbi.nlm.nih.gov] osteoarthritis necessitating joint replacement in young adults.[doi.org]

  • Malum Coxae Senilis

    Osteoarthritis ( arthrosis deformans, osteoarthrosis), also known as degenerative - productive changes in the joints is a syndrome which involves the premature wear and degeneration[ilucysoquy.cf] Based on the orientation of the joint, this premature contact typically occurs during hip flexion and/or internal rotation 7,8.[johnsnyderdpt.com] This abnormal contact has also been blamed for additional pathological conditions such as acetabular labral tears, chondral lesions, and osteoarthritis.[johnsnyderdpt.com]

  • Autosomal Dominant Rhegmatogenous Retinal Detachment

    STL1 systemic features of premature osteoarthritis, cleft palate, hearing impairment, and craniofacial abnormalities are either absent or very mild in STL1O patients.[abcam.com]

  • Pseudogout

    Forestier R; French Society for Rheumatology Osteoarthritis Section, Premature enthusiasm for the use of methotrexate for refractory chondrocalcinosis: comment on the article[dx.doi.org] Doan TH, Chevalier X, Leparc JM, Richette P, Bardin T, Forestier R, French Society for Rheumatology Osteoarthritis S Premature enthusiasm for the use of methotrexate for refractory[ncbi.nlm.nih.gov]

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