Undiagnosed NCAH may result in infertility, miscarriages, oligomenorrhea, hirsutism, acne, premature pubarche, testicular adrenal rest tumors, adrenal tumors, and voice problems
[ncbi.nlm.nih.gov]
The clinical consequences of NCAH expand from infancy, i.e. accelerated growth, to adolescence and adulthood, i.e. premature pubarche, cutaneous symptoms and oligo-ovulation
[ncbi.nlm.nih.gov]
J Clin Endocrinol Metab 85, 1678 - 1685 105 Marui, S. et al. ( 2000 ) Mutations in the type II 3beta-hydroxysteroid dehydrogenase (HSD3B2) gene can cause premature pubarche
[cambridge.org]