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58 Possible Causes for Primary Amenorrhea, Thick Facial Skin, Weight Gain

  • Polycystic Ovary Syndrome

    Cessation of VPA administration led to reduced weight gain and restored menstruation.[ncbi.nlm.nih.gov] […] of thick, darker, velvety skin.[en.wikipedia.org] amenorrhea; thus, this syndrome is unlikely if regular menses occurred for a time after menarche.[msdmanuals.com]

  • Acromegaly

    We report the case of a 43 years old patient initially diagnosed with acromegaly accompanied by weight gain and acral enlargement.[ncbi.nlm.nih.gov] The facial aspect is characteristic and includes a widened and thickened nose, prominent cheekbones, forehead bulges, thick lips and marked facial lines.[orpha.net] gain Surgery to remove the pituitary tumor that is causing this condition often corrects the abnormal GH.[nlm.nih.gov]

  • Prolactinoma

    Only two patients complained of recent weight gain at the initial consultation.[nature.com] Skin thickness and consistency was normal, without streaks. The patient was thick-skinned with normal distribution of skin thickness.[functionalneurology.com] Treatment with a dopamine agonist can be considered as the primary treatment with almost all microadenomas, including patients desiring pregnancy or those with primary amenorrhea[ncbi.nlm.nih.gov]

  • Virilization

    She gained 10 kg of body weight over the previous 2 years. Her past medical history was significant for mitral valve prolapse with no limitation of physical activity.[link.springer.com] Low level (common): Thick, dark facial hair in the beard or mustache area Increase in body hair Oily skin or acne Irregular menstrual periods Moderate level (uncommon): Male-pattern[mountsinai.org] The patient was admitted because of primary amenorrhea and signs of virilization at puberty. The chromosome analysis showed a 46, XY karyotype.[ncbi.nlm.nih.gov]

  • Hypothyroidism

    Symptoms include weight gain, constipation, dry skin, and sensitivity to the cold.[icd9data.com] […] expression, dementia or frank psychosis (myxedema madness) Dermatologic manifestations: Facial puffiness; myxedema; sparse, coarse and dry hair; coarse, dry, scaly and thick[merckmanuals.com] A syndrome of primary hypothyroidism, amenorrhea and galactorrhea. J Clin Endocrinol Metab 1968; 28: 591. 9.5.9.25.[ncbi.nlm.nih.gov]

  • Woodhouse Sakati Syndrome

    […] patches of thick, darker, velvety skin .[maria-online.com] Case report; In a 52-year-old woman from a consanguine pedigree we observed mental retardation, short stature, alopecia with absence of eyebrows, hypogonadism, primary amenorrhea[bib.irb.hr] She had a primary amenorrhea and alopecia. She had the same dysmorphic facial characteristics as her sister.[cags.org.ae]

  • Growth Hormone Deficiency

    gain.[ncbi.nlm.nih.gov] However, a nice side benefit is that growth hormone also increases the thickness of the skin.[drmarinajohnson.com] A Japanese senior high school girl aged 18 years and 5 months with growth hormone deficiency was referred for primary amenorrhea.[ncbi.nlm.nih.gov]

  • Secondary Hypothyroidism

    Total weight gain at this point is 50 pounds, I exercise, and eat a disgustingly healthy diet.[medhelp.org] […] speech 91 Eyelid edema 90 Cold sensation 89 Decreased sweating 89 Cold skin 83 Thick tongue 82 Facial edema 79 Coarse hair 76 Skin pallor 67 Forgetfulness 66 Constipation[aafp.org] A case study of a 15 year old girl who was diagnosed with a rare triad of primary amenorrhea, hypothyroidism, and Addison disease : An Unusual Cause of Primary Amenorrhea[physio-pedia.com]

  • Achard Thiers Syndrome

    Pregnancy causes weight gain and increases levels of estogen and placental hormones, which antagonize insulin. some medications such as thiazide diuretics, adrenal corticosteroids[checkorphan.org] The hair itself is sometimes not particularly thick, but the roots are very large which cause a noticeable shadow under the skin.[anagentherapies.co.uk] .), and signs of hyperandrogenism on the other (hirsutism, especially on the head and neck; menstrual changes such as oligomenorrhea and amenorrhea, clitoral enlargement,[symptoma.com]

  • Hyperpituitarism

    If the adrenocorticotropic hormone (ACTH) is involved, patient present with symptoms of excessive glucocorticoid secretion: hypertension, hirsutism, weight gain, acne, fatigability[symptoma.com] Serious physiological symptoms also may appear, such as increased sweating, thick and coarse oily skin, and chronic sinus congestion.[m.body-disease.com] […] secondary amenorrhea Galactorrhea Gynecomastia Cushing disease may include the following (see images below): A 16-year-old boy with Cushing disease.[emedicine.medscape.com]

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