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7 Possible Causes for Profound Atrophy in Fovea, Severely Reduced Central Responses on Multifocal ERG

  • Macular Dystrophy with Central Cone Involvement

    Stage 3 is characterized by one or more patches of well-demarcated RPE atrophy outside the fovea.[journalofoptometry.org] ERG responses to full-field testing are normal but multifocal studies reveal severely reduced central responses.[disorders.eyes.arizona.edu] In stage 4, the atrophic area involves the fovea which results in a profound decrease in vision.[journalofoptometry.org]

  • Cystoid Macular Dystrophy

    […] chorioretinal atrophy outside fovea Marked thinning of outer photoreceptor structures in atrophic zone; relative sparing of fovea Well-defined atrophic area of absent FAF[entokey.com] (geographic) atrophy affecting fovea Marked thinning of outer photoreceptor structures in atrophic zone including fovea Well-defined atrophic area of absent FAF affecting[entokey.com] […] outside fovea Visible remaining hyperfluorescent choroidal vessels in atrophic area Normal or cone/cone-rod dysfunction Stage 4 20/182 (20/400 – 20/33) Profound chorioretinal[entokey.com]

    Missing: Severely Reduced Central Responses on Multifocal ERG
  • Goldmann-Favre Syndrome

    […] plateau Multifocal ERG: preserved central responses but reduced with increasing eccentricity EOG light rise undetectable 5 OD: 6.5/6.5/5 OS: 6.5/6/4.5 Severely delayed and[iovs.arvojournals.org] reduced 40/36 Present OFF response plateau Multifocal ERG: preserved central responses but reduced with increasing eccentricity 6 OD: 56/ 100/8.5 Not detectable 10/10 NP[iovs.arvojournals.org] […] response to more peripheral hexagons 3 OD: 8/8.5/13.5 OS: 12.5/9.5/14 Delayed and reduced 6/6 NP NP — 4 OD: 6/6/7 OS: 7.5/6.5/6.5 Normal amplitude, delayed 50/46 Present OFF response[iovs.arvojournals.org]

    Missing: Profound Atrophy in Fovea
  • Occult Macular Dystrophy

    The multifocal ERGs 4 demonstrated a loss of local responses in the central retina (fig 2C).[bjo.bmj.com] However, focal macular ERGs with 5, 10, and 15 degrees stimulus spots 3 were severely reduced and essentially absent (fig 2B).[bjo.bmj.com]

    Missing: Profound Atrophy in Fovea
  • Sorsby's Fundus Dystrophy

    Stage 3 is characterized by one or more patches of well-demarcated RPE atrophy outside the fovea.[ncbi.nlm.nih.gov] In stage 4, the atrophic area involves the fovea which results in a profound decrease in vision.[ncbi.nlm.nih.gov]

    Missing: Severely Reduced Central Responses on Multifocal ERG
  • Peripheral Cone Dystrophy

    Multifocal electroretinography (mfERG) showed well-preserved local responses in the central retina and severely reduced responses in the perifoveal retina (Fig. 1) corresponding[journals.lww.com] The results of mfERGs showed slightly detectable responses in the central area of left eye; however, the amplitudes of the other area were severely reduced in the patients[link.springer.com] Full-field ERG disclosed normal scotopic responses in both eyes but diminished photopic amplitudes (Fig. 2).[journals.lww.com]

    Missing: Profound Atrophy in Fovea
  • Retinal Dystrophy

    Stage 3 is characterized by one or more patches of well-demarcated RPE atrophy outside the fovea.[ncbi.nlm.nih.gov] In stage 4, the atrophic area involves the fovea which results in a profound decrease in vision.[ncbi.nlm.nih.gov]

    Missing: Severely Reduced Central Responses on Multifocal ERG

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