Acromegaly
Craniofacial soft tissue and skeletal changes including mandibular prognathism and disturbed occlusion are typical manifestations of the disease process.[ncbi.nlm.nih.gov]
Facial skeleton elongation and mandibular overgrowth were combined with prognathism, malocclusion and overbite.[ncbi.nlm.nih.gov]
[…] of GH/IGF-I These include the following: Soft tissue swelling and enlargement of extremities Increase in ring and/or shoe size Hyperhidrosis Coarsening of facial features Prognathism[emedicine.medscape.com]
Autosomal Dominant Prognathism
Homepage Rare diseases Search Search for a rare disease Autosomal dominant prognathism Disease definition A rare, genetic, developmental defect during embryogenesis disorder[orpha.net]
Autosomal dominant prognathism in Orphanet.[ncbi.nlm.nih.gov]
Summary of "Genetic Factors Involved in Mandibular Prognathism."[bioportfolio.com]
Gigantism
It appears in childhood and many morphological signs lead us to suspect it: enlarged hands and feet, thick skin, a prominent chin (called prognathism), and an abnormal tendency[health.ccm.net]
What you'll see in someone with acromegaly is they get what's called frontal bossing [an enlarged forehead], prognathism--their jaw juts out--they get spreading of the teeth[scientificamerican.com]
Mucopolysaccharidosis
OBJECTIVE: The aim of this study was to quantify glycosaminoglycans (GAGs) in amniotic fluid (AF) from an MPS VII fetus compared with age-matched fetuses obtained from normal pregnancies. METHOD: Disaccharides were measured by liquid chromatography tandem mass spectrometry, compared to age-matched controls.[…][ncbi.nlm.nih.gov]
Smith-Magenis Syndrome
Radiographic findings suggest the prognathic appearance is not caused by excessive mandibular growth.[ncbi.nlm.nih.gov]
Their clinical manifestations included brachycephaly, midface hypoplasia, prognathism, upper lip eversion, short and broad hands with short fingers, clinodactyly of the fifth[ncbi.nlm.nih.gov]
Infants are described as looking "cherubic" with a Down syndrome-like appearance, whereas with age the facial appearance is that of relative prognathism.[ncbi.nlm.nih.gov]
Cockayne Syndrome
[…] giving the patient a prematurely old appearance, sparse hair, mental retardation, sensorineural deafness, blindness due to retinal degeneration, coarse voice, deep eyes, prognathism[whonamedit.com]
Sunburns easily · Retinopathy and/or cataracts (progressive) · Hearing loss (progressive) · Dental caries · Typical facial appearance: Pinched facies Sunken eyes Beaked nose Prognathism[cockayne-syndrome.net]
Micrognathism
Prognathism is most commonly due to a normal variation among phenotypes but can also be a result of inbreeding, thumb sucking, various genetic abnormalities and acromegaly[picdeer.com]
Answer is A: prognathism.[imgrumtag.com]
Ophthalmomandibulomelic Dysplasia orofacial cleft Prognathism Retrognathia Verloove-Vanhorick Brubakk Syndrome Weissenbacher-Zweymuller syndrome[rgd.mcw.edu]
Launois Syndrome
We report the first description of a Launois-Bensaude syndrome involving the orbit. Launois-Bensaude syndrome was diagnosed in a 70-year-old-man who presented with severe bilateral proptosis (Hertel value 26mm). We performed a bilateral transpalpebral orbital decompression by resection of intraorbital fat without[…][ncbi.nlm.nih.gov]
Mucopolysaccharidosis 1
Mucopolysaccharidosis 1 is a rare lysosomal storage disease provoked by mutations of the gene encoding for alpha-L-iduronidase, an enzyme required for the breakdown of determined glycosaminoglycans. Depending on the severity of the disease, patients may be diagnosed with Scheie syndrome, Hurler Scheie syndrome[…][symptoma.com]
Alpha-Mannosidosis
The facial trait include large head with prominent forehead, rounded eyebrows, flattened nasal bridge, macroglossia, widely spaced teeth, and prognathism.[ncbi.nlm.nih.gov]
Clinical findings Macrocephaly, thickened calvaria, coarse face, macroglossia, wide-spaced teeth, prognathism, deafness, mental retardation, hepatosplenomegaly.[medical-dictionary.thefreedictionary.com]
The facial dysmorphism is marked by a large head with a prominent forehead, rounded eyebrows, a flattened nasal bridge, macroglossia, widely spaced teeth, and prognathism.[orpha.net]