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827 Possible Causes for Prognathism

  • Acromegaly

    Craniofacial soft tissue and skeletal changes including mandibular prognathism and disturbed occlusion are typical manifestations of the disease process.[ncbi.nlm.nih.gov] Facial skeleton elongation and mandibular overgrowth were combined with prognathism, malocclusion and overbite.[ncbi.nlm.nih.gov] […] of GH/IGF-I These include the following: Soft tissue swelling and enlargement of extremities Increase in ring and/or shoe size Hyperhidrosis Coarsening of facial features Prognathism[emedicine.medscape.com]

  • Gigantism

    It appears in childhood and many morphological signs lead us to suspect it: enlarged hands and feet, thick skin, a prominent chin (called prognathism), and an abnormal tendency[health.ccm.net] What you'll see in someone with acromegaly is they get what's called frontal bossing [an enlarged forehead], prognathism--their jaw juts out--they get spreading of the teeth[scientificamerican.com]

  • Smith-Magenis Syndrome

    Radiographic findings suggest the prognathic appearance is not caused by excessive mandibular growth.[ncbi.nlm.nih.gov] Their clinical manifestations included brachycephaly, midface hypoplasia, prognathism, upper lip eversion, short and broad hands with short fingers, clinodactyly of the fifth[ncbi.nlm.nih.gov] Infants are described as looking "cherubic" with a Down syndrome-like appearance, whereas with age the facial appearance is that of relative prognathism.[ncbi.nlm.nih.gov]

  • Cockayne Syndrome

    Sunburns easily · Retinopathy and/or cataracts (progressive) · Hearing loss (progressive) · Dental caries · Typical facial appearance: Pinched facies Sunken eyes Beaked nose Prognathism[cockayne-syndrome.net]

  • Alpha-Mannosidosis

    The facial trait include large head with prominent forehead, rounded eyebrows, flattened nasal bridge, macroglossia, widely spaced teeth, and prognathism.[ncbi.nlm.nih.gov] Clinical findings Macrocephaly, thickened calvaria, coarse face, macroglossia, wide-spaced teeth, prognathism, deafness, mental retardation, hepatosplenomegaly.[medical-dictionary.thefreedictionary.com] The facial dysmorphism is marked by a large head with a prominent forehead, rounded eyebrows, a flattened nasal bridge, macroglossia, widely spaced teeth, and prognathism.[orpha.net]

  • Autosomal Recessive Osteopetrosis 3

    Some affected individuals may experience abnormal protrusion of the lower jaw (mandibular prognathism), dental anomalies, baby teeth that do not fall out (deciduous retention[rarediseases.org]

  • Van Buchem Disease

    The mandible is massive, prognathic, often asymmetric, and with an obtuse angle. The clavicles and ribs are broadened and dense because of cortical thickening.[slideheaven.com] The mandible is prognathic, broadened and squared, and dental malocclusion is frequent [224]. The face may be distorted with relative midfacial hypo- 403 plasia.[slideheaven.com] Mild autosomal recessive osteopetrosis This rare form is characterized by short stature, increased upper/lower segment ratio, mandibular prognathism, fractures following minimal[slideheaven.com]

  • Angelman Syndrome

    The syndrome has oral manifestations such as diastemas, tongue thrusting, sucking/swallowing disorder, mandibular prognathism, a wide mouth, frequent drooling, and excessive[ncbi.nlm.nih.gov] The syndrome has oral manifestations such as diastemas, tongue thrusting, sucking/swallowing disorder, mandibular prognathism, and wide mouth.[ncbi.nlm.nih.gov] These include microcephaly, brachycephaly, a palpable occipital groove, prognathism, and wide spaced teeth.[ncbi.nlm.nih.gov]

  • Cleidocranial Dysplasia

    […] craniofacial features of CCD that stand out are a patency of the anterior fontanelle, an inverted pear-shaped calvaria, a hypertelorism, a general midface retrusion, and a mandible prognathism[ncbi.nlm.nih.gov] Depressed malar process and relative mandibular prognathism were seen in all the cases [Figure 1] .[joomr.org] […] autosomal dominant condition marked by a pointed or conical skull, protruding wide-set eyes, strabismus, parrot-beaked nose, and hypoplastic maxilla with relative mandibular prognathism[medical-dictionary.thefreedictionary.com]

  • Mucopolysaccharidosis

    Although enzyme replacement therapy (ERT) is an effective treatment for mucopolysaccharidosis (MPS) types I, II, IVA and VI, its effectiveness in children with central nervous system (CNS) disorders is said to be poor because the blood-brain barrier cannot be penetrated by ERT drugs. To assess CNS involvement in[…][ncbi.nlm.nih.gov]

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