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1,034 Possible Causes for Progressive Contractures, Weight Loss

  • Non-Small Cell Lung Carcinoma

    A 56-year-old man presented with pain and stiffness in both shoulders and developed severe, rapidly progressive contractures of the fingers.[ncbi.nlm.nih.gov] loss and loss of appetite Shortness of breath Feeling tired or weak Infections such as bronchitis and pneumonia that don’t go away or keep coming back New onset of wheezing[cancer.org] Some of the symptoms of less advanced cancer include chronic cough, coughing up blood, chest pain, hoarseness, shortness of breath, wheezing, chest pain, weight loss, and[en.wikipedia.org]

  • Chronic Alcoholism

    Acute renal failure secondary to progressively decreasing renal blood flow (hepatorenal syndrome) may develop.[merckmanuals.com] The first had been admitted with confusion and weight loss, the second with hypotension and sepsis, and the third with confusion and hypoglycaemia-induced seizures.[ncbi.nlm.nih.gov] OBJECTIVE: Diarrhea, weight loss and osteoporosis are prominent symptoms and clinical signs of alcoholism.[ncbi.nlm.nih.gov]

  • Polyarthritis

    The characteristic rapid progression of palmar contracture is a key finding that suggests the potential existence of a malignancy. [Indexed for MEDLINE] Free full text[ncbi.nlm.nih.gov] loss eventually led to the diagnosis of metastatic pancreatic adenocarcinoma.[ncbi.nlm.nih.gov] […] to flexion contracture of the hands.[ncbi.nlm.nih.gov]

  • Alcoholic Liver Disease

    Acute renal failure secondary to progressively decreasing renal blood flow (hepatorenal syndrome) may develop.[merckmanuals.com] Commonly reported symptoms include: * Nausea and vomiting * Abdominal pain * Jaundice * Weight loss or weight gain * Bloody or dark bowel movements * Mood changes including[alcoholrehab.com] Nutritional therapy helps to reverse muscle wasting, weight loss, vitamin deficiencies, and trace element deficiencies associated with ALD.[ncbi.nlm.nih.gov]

  • Eosinophilic Fasciitis

    He presented with progressive painless joint contractures of his right wrist and fingers, and reduced muscle strength of his right arm, without obvious skin changes.[ncbi.nlm.nih.gov] Fatigue and weight loss are common. Rarely, aplastic anemia, thrombocytopenia, and lymphoproliferative processes develop.[merckmanuals.com] Other signs and symptoms that may be present include: Malaise, weakness, fever and weight loss Joint contractures of the elbows, wrists, ankles, knees and shoulders Carpal[dermnetnz.org]

  • Rheumatoid Arthritis

    Erosion of the articular cartilage, together with ligamentous changes, result in deformity and contractures. As the disease progresses, pain and deformity increase.[orthoinfo.aaos.org] loss (weighted mean difference -3.23, 95% CI -4.79 to -1.67 kg) in the diet groups compared to the control groups.[ncbi.nlm.nih.gov] Flexion contractures may require intensive exercise, casting, or immobilization (eg, splinting) in progressively more stretched-open positions.[merckmanuals.com]

  • Juvenile Rheumatoid Arthritis

    Destructive surface changes contribute to pain and loss of motion, while ongoing growth disturbances and contractures produce further deformity (Figure 1).[healio.com] Low-grade fever, weight loss, and anemia may occur, as well as growth problems in severe cases.[arthritis.about.com] […] changed In some cases, symptoms of juvenile arthritis are mild and do not progress to more severe joint disease and deformities.[orthoinfo.aaos.org]

  • Arthritis

    Flexion contractures may require intensive exercise, casting, or immobilization (eg, splinting) in progressively more stretched-open positions.[merckmanuals.com] Even small amounts of weight loss -- 10 pounds or so -- can cut the risk of knee osteoarthritis, particularly among women, so efforts to treat and prevent obesity could help[web.archive.org] In one study, a 10% weight loss led to a 28% improvement in function.[takingcharge.csh.umn.edu]

  • Diffuse Scleroderma

    With disease progression, ulcerations over joints and flexion contractures of the fingers, wrists, and elbows may occur.[aafp.org] loss, pruritis Skin thickening - no or minimal progression Skin thickening - rapid progression, usually reaching peak involvement within 2 years Organs affected - Reynaud's[barts.wikia.com] […] skin disease, 15 high skin score, 11 large joint contractures, 11 presence of anti-RNA-polymerase antibody, 14 and 16 These risk factors may relate to disease severity, rather[doi.org]

  • Systemic Scleroderma

    With disease progression, ulcerations over joints and flexion contractures of the fingers, wrists, and elbows may occur.[aafp.org] Lastly, substances used to minimize appetite and contribute to weight loss (derivatives of phenylethylamine ) are also believed to trigger systemic sclerosis.[symptoma.com] […] skin disease, 15 high skin score, 11 large joint contractures, 11 presence of anti-RNA-polymerase antibody, 14 and 16 These risk factors may relate to disease severity, rather[doi.org]

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