Progressive Dementia: Causes & Reasons

Possible Causes for Progressive Dementia

We report a case of progressive dementia in which the differentiation of DLB and Alzheimer disease (AD) on the basis of clinical criteria alone was not possible. [ncbi.nlm.nih.gov]

It is established that chronic spirochetal infection can cause slowly progressive dementia, brain atrophy and amyloid deposition in late neurosyphilis. [ncbi.nlm.nih.gov]

Abstract We report a 44-year-old woman, with a family history of early-onset dementia, presenting with primary progressive aphasia. [ncbi.nlm.nih.gov]

Binswanger Disease

or (3) slowly progressive dementia alone, three patients. [jamanetwork.com]

Lewy Body Dementia Lewy body dementia (LBD) is one of the most common types of progressive dementia. [alzheimersweekly.com]

The main clinical manifestations of progressive dementia. 【clinical points] 1. 2/3. chronic disease, and 1/3 for the acute onset. [e.uuuwell.com]

Creutzfeldt Jakob Disease

Rapidly progressive dementias (RPDs) are dementias that progress quickly, typically over the course of weeks to months, but sometimes up to two to three years. [memory.ucsf.edu]

In the final stage of the disease, all patients presented rapidly progressive dementia and myoclonus. [ncbi.nlm.nih.gov]

Amy May Lin Quek and Andrew McKeon, Rapidly Progressive Dementia and its Mimics, Dementia, (15-34), (2013). [doi.org]

Alcohol Dementia

Moderate alcohol consumption has been linked with reduced risk of vascular disease, and good vascular health could slow the progression of dementia. [content.time.com]

In most cases, dementia is progressive, getting worse over time. Dementia progresses differently in everyone. [healthline.com]

Adults age 72 and older with mild cognitive impairment (MCI) who drank more than 14 alcoholic drinks a week were 72% more likely to progress to dementia over an eight-year [hsph.harvard.edu]

Vascular Dementia

We present a case report of a 50-year-old man with migraines associated with left-sided weakness since age 34 years, a stroke at age 43 years, followed by progressive dementia [ncbi.nlm.nih.gov]

Prion diseases, such as Creutzfeldt-Jakob disease, are the most common cause of rapidly progressing dementias. [my.clevelandclinic.org]

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) disease, a genetically determined arteriopathy, is a rare cause of vascular dementia [ncbi.nlm.nih.gov]

Multi-Infarct Dementia

We included only those cases with progressive dementia clinically diagnosed as Alzheimer's disease (AD) or multi-infarct dementia, in whom autopsy revealed only cerebral infarction [ncbi.nlm.nih.gov]

We report on a 55-year-old man suffering from progressive dementia and PAPS, in whom cerebral glucose metabolism and blood flow were examined by positron emission tomography [ncbi.nlm.nih.gov]

[…] autopsy cases of vascular dementia from 10 university neuropathology laboratories. [n.neurology.org]

Dialysis Dementia

[…] compounds in the dialysis fluid), and is marked especially by motor and speech disturbance (as dysarthria and myoclonus), progressive dementia, and seizures [merriam-webster.com]

The proposal that PGD(2)S contributes to progression of renal failure and dialysis dementia is based on: (1) the progressive creatinine-like increase in PGD(2)S levels in [ncbi.nlm.nih.gov]

dementia." [ncbi.nlm.nih.gov]

Hallervorden-Spatz Syndrome

Serial assessments of a 29-year-old woman showed progressive dementia. [ncbi.nlm.nih.gov]

dementia. [radiopaedia.org]

We studied a 27-year-old woman who died after a 6-year history of progressive dementia, dystonia, ataxia, apraxia, spasticity, choreoathetosis, visual and auditory hallucinations [ncbi.nlm.nih.gov]

Dementia with Lewy Bodies

We suggest the possibility of progression to dementia with Lewy bodies, but not AD or posterior cortical atrophy. [ncbi.nlm.nih.gov]

Disease Progression Lewy body dementia does not progress the same way Alzheimer's disease does. [verywellhealth.com]

Definition Dementia with Lewy bodies (DLB) is one of the most common types of progressive dementia. [ninds.nih.gov]

Unverricht-Lundborg Syndrome

We report three new clinical features of ULD; ocular motor apraxia, dystonia, and rapidly progressive dementia. [hanyang.elsevierpure.com]

Alpha-synuclein multiplications with parkinsonism, dementia or progressive myoclonus? [mayoclinic.pure.elsevier.com]

Dementia, progressive Progressive dementia [ more ] 0000726 Intellectual disability Mental deficiency Mental retardation Mental retardation, nonspecific Mental-retardation [rarediseases.info.nih.gov]

Boxer's Dementia

Binswanger's dementia a progressive dementia of presenile onset due to demyelination of the subcortical white matter of the brain, with sclerotic changes in the blood vessels [medical-dictionary.thefreedictionary.com]

Progressive dementias Types of dementias that progress and aren't reversible include: Alzheimer's disease. Alzheimer's disease is the most common cause of dementia. [mayoclinic.org]

dementia. [bu.edu]

Pick Disease of The Brain

Frontotemporal dementia progresses steadily and often rapidly and is fatal. [medicinenet.com]

As this genetically-inherited disease progresses, dementia develops. Everyone is born with this gene. [goinggentleintothatgoodnight.com]

Considering the MRI and CSF findings we first diagnosed multiple sclerosis with a prominent picture of progressive dementia. [jnnp.bmj.com]

Progressive Supranuclear Palsy

The progression to dementia at the 3-year follow-up was assessed. [ncbi.nlm.nih.gov]

[…] supranuclear palsy (PSP), but their relevance and the progression to dementia are still poorly described. [karger.com]

The `subcortical dementia' of progressive supranuclear palsy Martin L. Albert, Robert G. Feldman, Anne L. [doi.org]

Drug-Induced Dementia

Lewy body dementia is similar to Alzheimer's but may progress more rapidly. [healthcommunities.com]

(a.k.a., drug-induced dementia) often presents with a pattern of neuropsychological deficits that are different than those seen in AD including a lack of clinical progression [neurotoxicants.com]

In progressive dementias such as AD, the person may ultimately become completely dependent. [medical-dictionary.thefreedictionary.com]

AIDS Dementia Complex

Rapidly Progressive Dementia. Ann Neurol 2008; 64:97-108. Roberson ED, Hesse JH, Rose KD, et al. [medicaljournal.gazi.edu.tr]

While our patient was being followed up with the diagnosis of dementia and parkinsonism, clinical signs rapidly progressed. [acarindex.com]

Abstract Of 70 autopsied patients with the acquired immune deficiency syndrome (AIDS), 46 suffered progressive dementia that was frequently accompanied by motor and behavioral [pubmed.ncbi.nlm.nih.gov]

Cerebrotendinous Xanthomatosis

Summary History and clinical findings: A 43-year-old woman had since childhood suffered from progressive dementia. [thieme-connect.com]

Cholestanol and cholesterol accumulate in many tissues, including brain (primarily white matter), leading to progressive neurological dysfunction marked by dementia, spinal [ncbi.nlm.nih.gov]

Neurologic sequela of the disease is progressive, which includes epilepsy, peripheral neuropathy, ataxia, and dementia. [ncbi.nlm.nih.gov]

Lafora Disease

He exhibited rapidly progressive dementia/cognitive decline, apraxia, difficult speech behavioral change, depression, confusion, ataxia (difficulty controlling muscles), and [ijnpnd.com]

As the disease progresses, dementia sets in. Additionally, the associate seizures worsen and become more difficult to treat. [blog.sermo.com]

Lafora’s disease is clinically characterised by the triad of epilepsy, progressive dementia, and myoclonus as well as Lafora bodies in the brain and other tissues. [jnnp.bmj.com]

Niemann-Pick Disease Type C

A 39-year-old female presented to the Bryan Memory Disorders Clinic at Duke University with a 7-year history of an atypical progressive dementia, mildly impaired vertical [ncbi.nlm.nih.gov]

Pathogenic variants of the NPC1 or NPC2 genes yield highly variable phenotypes with a time course that ranges from fetal onset (i.e., hydrops fetalis) to progressive dementia [ncbi.nlm.nih.gov]

Abstract Adult patients with Niemann-Pick disease type C (NPC) usually develop cognitive impairment progressing to dementia, whose pathophysiology remains still unclear. [ncbi.nlm.nih.gov]

Adult Neuronal Ceroid Lipofuscinosis

Firstly, their clinical presentation can mimic several other rare causes of progressive myoclonic epilepsy or dementia with motor deterioration. [jnnp.bmj.com]

There are several subtypes based on mutations of the various genes, time of disease onset, and severity of the neurological defects such as progressive dementia; seizures; [icd10data.com]

The clinical presentation of Kufs disease involves any combination of progressive dementia, epilepsy, myoclonus, cerebellar and/or extrapyramidal signs. [jnnp.bmj.com]

Diffuse Cerebral Sclerosis of Schilder

dementia. [ninds.nih.gov]

The clinical course tends to be progressive and includes dementia, cortical blindness, cortical deafness, spastic hemiplegia, and pseudobulbar palsy. [rareomics.healx.io]

Symptoms may include progressive stiffness, weakness or paralysis of the lower limbs, and ataxia. [ninds.nih.gov]

Neurosyphilis

Neurosyphilis is rather an unusual cause of dementia characterized by a rapidly progressive course and psychiatric symptoms. [ncbi.nlm.nih.gov]

Neurosyphilis should not be overlooked as an etiology for progressive dementia even in this post-antibiotic era. [ncbi.nlm.nih.gov]

We report a case of a 42-year-old Russian man living in Estonia with rapidly progressive dementia and movement disorders manifesting as myoclonus, cerebellar ataxia and parkinsonism [ncbi.nlm.nih.gov]

Neuronal Ceroid Lipofuscinosis Type 3

There are several subtypes based on mutations of the various genes, time of disease onset, and severity of the neurological defects such as progressive dementia; seizures; [icd10data.com]

dementia, seizures, and progressive visual failure (Mole et al., 2005; pubmed:15965709 ). [flybase.org]

The clinical course is characterized by progressive visual failure, dementia, and seizures. [pediatricneurologybriefs.com]

Organic Brain Syndrome

Alzheimer's disease, Lewy body dementia and frontotemporal dementia are all forms of progressive dementia. [nmihi.com]

Unable to plan a meal or balance a check book Inability to use objects correctly Progression of Dementia Phase 2 Progression of difficulty interacting in social situations [quizlet.com]

F02.0* Dementia in Pick's disease ( G31.0+ ) A progressive dementia, commencing in middle age, characterized by early, slowly progressing changes of character and social deterioration [apps.who.int]

Meningovascular Syphilis

General paresis is characterized by progressive DEMENTIA; DYSARTHRIA; TREMOR; MYOCLONUS; SEIZURES; and Argyll-Robertson pupils. [fpnotebook.com]

Clinical features include progressive dementia, which is frequently accompanied by psychotic symptoms, personallity change, dysphoric or elevated mood and striking lapses [alzheimer-europe.org]

Signs and symptoms include abnormal gait, blindness, depression, paralysis, seizures and dementia. [fpnotebook.com]

Cerebral Cortical Atrophy

(bvFTD), progressive non-fluent aphasia (PNFA) (or a mixed aphasia) and semantic dementia (SD) [ 7 ]. [omicsonline.org]

Moreover, the relative sparing of the hippocampus, comparable to that found in cases with focal progressive dementia, suggests that the dementing process may involve different [link.springer.com]

Dementia is characterized by a progressive impairment of memory and intellectual function that is severe enough to interfere with social and work skills. [ninds.nih.gov]

Normal Pressure Hydrocephalus

dementia like symptoms as the fluid builds up. [neurologywestla.com]

Historical note and terminology The triad of progressive dementia, gait disturbances, and urinary incontinence was originally described as a distinct syndrome by Adams and [medlink.com]

dementia without gait disturbance  (even if the ventricles are enlarged)  ● Lack of progression of symptoms 13. [slideshare.net]

Neurologic Manifestation of Whipple Disease

Clinical presentation Clinical features are non-specific and include: progressive dementia external ophthalmoplegia myoclonus seizures ataxia hypothalamic dysfunction (e.g [radiopaedia.org]

A progressive dementia may be seen, but the pathognomonic signs of CNS disease, when present, are oculomasticatory myorhythmia and oculofacial-skeletal myorhythmia. [enotes.tripod.com]

dementia, seizures, personality changes, and meningitis. [eportal.mountsinai.ca]

Fatal Familial Insomnia

A 63-year-old man who had a history of gait ataxia developed rapidly progressive dementia with mild dysautonomic features. [ncbi.nlm.nih.gov]

This case is a compelling example that even with evidence of leukoencephalopathy, prion disease should be an important differential diagnosis of rapidly progressive dementia [ncbi.nlm.nih.gov]

He presented with intractable insomnia, rapidly progressive dementia and autonomic disturbances. [karger.com]

Refsum Disease

and elevated blood pressure came to medical attention because of progressive dementia and walking difficulties. [ncbi.nlm.nih.gov]

Discussion We report the very unusual case of a 72-year-old woman presenting with 2 years’ history of progressive dementia, walking problems, and diffuse leukoencephalopathy [ncbi.nlm.nih.gov]

dementia, gait apraxia, and memory loss, associated with diffuse leukoencephalopathy. [ncbi.nlm.nih.gov]

Alpers Syndrome

Dementia, progressive Progressive dementia [ more ] 0000726 Elevated hepatic transaminase High liver enzymes 0002910 Epilepsia partialis continua 0012847 Ethylmalonic aciduria [rarediseases.info.nih.gov]

The clinical course tends to be progressive and includes dementia, cortical blindness, cortical deafness, spastic hemiplegia, and pseudobulbar palsy. [hon.ch]

Symptoms of Alpers include EPC, organ failure, strokes, hypotonia (low muscle tone) – leading to quadriplegia, spasticity, progressive dementia, blindness and deafness. [hughie.org.au]