Progressive Disease: Causes & Reasons

Warning: Do not use in emergencies, if pregnant, if under 18, or as a substitute for a doctor’s advice or diagnosis. Learn more

Possible Causes for Progressive Disease

Lupus Nephritis WHO Class 6

Black patients with lupus nephritis are also at higher risk of progression to end-stage renal disease. [msdmanuals.com]

- IgA nephropathy - Lupus nephritis - Diabetic nephropathy - Rapidly progressive glomerulonephritis Tubulointerstitial diseases of the kidney Interstitial nephritis - Pyelonephritis [bionity.com]

[…] and more extensive histopathologic changes) and progress to end stage kidney disease. [en.wikipedia.org]

Geographic Atrophy

Central vision loss can be a key indicator of disease progression. [spherixglobalinsights.com]

Clinical Symptoms Progression rate for GA is slow comparing to neovascular AMD (n-AMD), but disease progression is steady over years. [vtc.meduniwien.ac.at]

AMD is a progressive eye disease. Each eye may be in a different stage. Advanced AMD is the last stage of this progressive retinal disease. [webrn-maculardegeneration.com]

Chronic Kidney Insufficiency

[…] the risk factors for disease progression and cardiovascular complications. [karger.com]

The majority of patients with chronic kidney disease rarely progress beyond Stage 2. [medicalnewstoday.com]

Navaneethan SD, Yehnert H: Bariatric surgery and progression of chronic kidney disease. [bmcnephrol.biomedcentral.com]

Primary Progressive Multiple Sclerosis

The majority of patients starts with relapsing remitting (RR) disease; approximately 50-60% of these patients progress to secondary progressive (SP) disease. [ncbi.nlm.nih.gov]

METHODS: A systematic literature research was performed to identify predictors for disease progression in PPMS. [ncbi.nlm.nih.gov]

[…] and disability progression in primary progressive multiple sclerosis: a cohort study. ( 30298572 ) Lorscheider J...MSBase Study Group 2018 22 Disease-Modifying Therapies [malacards.org]

Progressive Myoclonic Epilepsy Type 3

Category Nervous system disease Brite Human diseases [BR: br08402 ] Nervous system diseases Epilepsy H00810 Progressive myoclonic epilepsy Human diseases in ICD-11 classification [genome.jp]

[…] gene sharing: Search GEO for disease gene expression data for Epilepsy Progressive Myoclonic Type 3. [malacards.org]

Entry H00810 Disease Name Progressive myoclonic epilepsy Subgroup Lafora disease [DS:H01994] Unverricht-Lundborg disease [DS:H01995] Neuronal ceroid lipofuscinoses [DS:H00149 [genome.jp]

Lafora Disease

Daily living activities and social interaction were preserved in all cases and, overall, the progression of the disease was slow. [ncbi.nlm.nih.gov]

Citation metadata Abstract : Lafora disease is a rare autosomal recessive progressive myoclonic epilepsy characterized by seizures, myoclonus and progressive cognitive decline [go.gale.com]

In this work, we characterize the mutations present in the EPM2A gene in a patient displaying a slow progression form of the disease. [ncbi.nlm.nih.gov]

Unverricht-Lundborg Syndrome

This disease is classified as a type of progressive myoclonus epilepsy. [ivami.com]

Entry H00810 Disease Name Progressive myoclonic epilepsy Subgroup Lafora disease [DS: H01994 ] Unverricht-Lundborg disease [DS: H01995 ] Neuronal ceroid lipofuscinoses [DS [genome.jp]

Progressive Myoclonic Epilepsy Type 7

Disease Ontology Browser progressive myoclonus epilepsy 6 (DOID:0111449) Alliance: disease page Synonyms: EPM6; GOSR2-related progressive myoclonus ataxia; North Sea progressive [informatics.jax.org]

Search GEO for disease gene expression data for Epilepsy Progressive Myoclonic Type 3. [malacards.org]

J Kor Neurol Ass 17(3):420 ~ 426, 1999 Key Words : Gaucher’s disease, progressive myoclonus epilepsy, ß-glucosidase [jkna.org]

Progressive Myoclonic Epilepsy Type 8

Citation metadata Abstract : Lafora disease is a rare autosomal recessive progressive myoclonic epilepsy characterized by seizures, myoclonus and progressive cognitive decline [go.gale.com]

A type of progressive myoclonic epilepsy, Lafora disease: A case report. Eastern J Med. 2013; 18(1): 34-36 [eastjmed.org]

Primary Sclerosing Cholangitis

Primary sclerosing cholangitis (PSC) is a chronic, progressive disease characterized by inflammatory and fibrosing strictures of the biliary tree. [ncbi.nlm.nih.gov]

[…] of the disease. [ncbi.nlm.nih.gov]

As the disease progresses, the liver may become nodular in appearance. [symptoma.com]

Progressive Bulbar Paralysis

Progressive bulbar paralysis of childhood (Fazio-Londe disease). Ind Pediatr 1982; 19: 805–806. Google Scholar 3. [link.springer.com]

[…] bulbar palsy. ( 8270924 ) Chancellor A.M....Swingler R.J. 1993 8 Progressive bulbar palsy: a case report of a type of motor neuron disease presenting with oral symptoms. [malacards.org]

Bulbar, Progressive Bulbar Palsies, Progressive Bulbar Palsy, Bulbar Palsy, Progressive [Disease/Finding], bulbar palsies, bulbar palsy progressive, bulbar palsy, bulbar [fpnotebook.com]

Progressive Muscular Atrophy

[…] muscular atrophy have a relentlessly progressive disease course. [ncbi.nlm.nih.gov]

Klinefelter's syndrome associated with progressive muscular atrophy simulating Kennedy's disease. [annalsofian.org]

What Is Progressive Muscular Atrophy? Progressive muscular atrophy is an inherited form of motor neuron disease. [healthcare.utah.edu]

Amyotrophic Lateral Sclerosis Type 1

Amyotrophic Lateral Sclerosis (ALS), commonly known as Lou Gehrig's disease, is a progressive neuromuscular disease. [hopkinsmedicine.org]

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. [alsa.org]

ALS is a progressive disease, which means it gets worse over time. It affects nerves in your brain and spinal cord that control your muscles. [webmd.com]

Idiopathic Pulmonary Fibrosis

However, accelerated disease progression after nintedanib discontinuation has never been reported. [ncbi.nlm.nih.gov]

disease progression, and indication for lung transplantation. [ncbi.nlm.nih.gov]

IPF is a progressive disease marked by scarring of the lung tissue. [my.clevelandclinic.org]

Amyotrophic Lateral Sclerosis

This review examined current research related to moderate exercise for maintaining independence without accelerating disease progression in persons with ALS. [ncbi.nlm.nih.gov]

PMID: 19556916 Issn Print: 1557-0576 Publication Date: 2009/06/01 Checking for direct PDF access through Ovid Abstract Amyotrophic lateral sclerosis (ALS) is an idiopathic disease [doi.org]

Amyotrophic Lateral Sclerosis (ALS), commonly known as Lou Gehrig's disease, is a progressive neuromuscular disease. [hopkinsmedicine.org]

Pulmonary Fibrosis

However, accelerated disease progression after nintedanib discontinuation has never been reported. [ncbi.nlm.nih.gov]

IPF is a progressive disease marked by scarring of the lung tissue. [my.clevelandclinic.org]

Accelerated disease progression after the discontinuation of nintedanib therapy for IPF. One patient received steroid therapy. [ncbi.nlm.nih.gov]

Primary Lateral Sclerosis

Primary lateral sclerosis (PLS) is a progressive, degenerative disease of upper motor neurons characterized by progressive spasticity (ie, stiffness). [emedicine.com]

Patients with primary lateral sclerosis (PLS) have a slower progression of disease and different clinical spectrum. [ncbi.nlm.nih.gov]

Classification and terminology of motor neuron diseases Motor neuron diseases (MNDs) are progressive degenerative diseases in which death of the cell bodies of motor neurons [emedicine.com]

Progressive Supranuclear Palsy

The current gold standard for measuring clinical disease progression in PSP is the PSP Rating Scale score. [ncbi.nlm.nih.gov]

The ability to assess the distribution and extent of tau pathology in Alzheimer's disease and progressive supranuclear palsy in vivo would help to develop biomarkers for these [ncbi.nlm.nih.gov]

PSP-RS, Progressive Supranuclear Palsy-Richardson's Syndrome; Parkinson's disease; Progressive Supranuclear Palsy; ROC, receiver operating characteristics; SCP, superior [ncbi.nlm.nih.gov]

Progressive Familial Intrahepatic Cholestasis

Category Digestive system disease Brite Human diseases [BR: br08402 ] Digestive system diseases Liver diseases H00624 Progressive familial intrahepatic cholestasis Human diseases [genome.jp]

Category Digestive system disease Brite Human diseases [BR:br08402] Digestive system diseases Liver diseases H00624 Progressive familial intrahepatic cholestasis Human diseases [genome.jp]

[…] of cholestasis that progresses to hepatic fibrosis, cirrhosis, and end-stage liver disease before adulthood. [malacards.org]

Classic Progressive Supranuclear Palsy Syndrome

Not Applicable tideglusib;tideglusib;placebo 44 Deep TMS for the Treatment of Patients With Parkinson's Disease and Progressive Supranuclear Palsy Completed NCT02734485 Not [malacards.org]

The progression of the disease is slow between 5 to 10 years. The age of onset is typically over 50 years old. The duration of the disease is 7 years. [alzheimer-europe.org]

[…] palsy Steele-Richardson-Olszewski disease tau protein Statistics from Altmetric.com progressive supranuclear palsy Steele-Richardson-Olszewski disease tau protein Progressive [pmj.bmj.com]

Motor Neuron Disease

The aim of the study was to explore the prevalence of VGKC-complex Abs in slow-progression motor neuron disease (MND). [ncbi.nlm.nih.gov]

Here we illustrate a 74-year-old patient presenting with clinical signs of slowly progressive motor neuron disease. [ncbi.nlm.nih.gov]

Abstract We have performed whole-exome sequencing in a family trio with a 16-year-old girl suffering of progressive motor neuron disease. [ncbi.nlm.nih.gov]

Erb Muscular Dystrophy

It is a progressively crippling disease with onset in childhood or adolescence and is usually inherited as an autosomal-recessive trait. It affects both sexes. [medical-dictionary.thefreedictionary.com]

The progression of the disease is very slow, and patients have a normal life expectancy. [checkorphan.org]

Inherited disease that causes progressive weakness in the skeletal (and occasionally heart) muscle. [seslisozluk.net]

Diabetic Nephropathy

Diabetic nephropathy (DN) is a progressive disease that affects about one third of diabetic patients and is among the most frequent causes of the end stage renal disease [ncbi.nlm.nih.gov]

Disease progression depends on many factors. [healthline.com]

Diabetic nephropathy progresses slowly. With early treatment, you can slow or even stop the progression of the disease. [healthline.com]

Chronic Kidney Disease

It is generally believed that significant renal ablation leads to hyperfiltration and eventually progressively worsening chronic kidney disease. [ncbi.nlm.nih.gov]

OBJECTIVES: To assess the cost effectiveness of renin-angiotensin aldosterone system (RAAS) blockade in the progression of chronic kidney disease using Thai clinical data [ncbi.nlm.nih.gov]

Unless intensive intervention is initiated, some patients can rapidly progress to end-stage kidney disease. [ncbi.nlm.nih.gov]

Alpers Syndrome

These findings correlate with the progressive cognitive decline seen with the progression of the disease. The hepatic findings are more specific to AHS. [ncbi.nlm.nih.gov]

With the progression of the disease, motor skills, and muscle strength declines, necessitating the services of physical therapy and occupational therapy. [statpearls.com]

In all, with seizure onset the course of the disease rapidly progressed. [dovepress.com]

Degenerative Brain Disorder

"This is a rapidly progressing disease, so any drug that could slow down the degenerative process would give people the option to live longer." [news.xinhuanet.com]

progression.3-5With markers of clinical disease progression integral to the measurement of efficacy of disease-modifying therapies, a team of investigators led by Professor [quanterix.com]

Can CSF and plasma neurofilament light chain predict disease progression in progressive supranuclear palsy? [neurologyadvisor.com]

Pick Disease of The Brain

Pick’s disease, also known as Pick disease or PiD, is a rare neurodegenerative disorder involving the progressive destruction of brain cells. [news-medical.net]

and progressive supranuclear palsy. [indiana.pure.elsevier.com]

It is a progressive, degenerative disease that attacks the brain and results in impaired memory, thinking, and behavior. [health.uconn.edu]

Kienbock Disease

Abstract Kienbock's disease, or avascular necrosis of the lunate, is a progressive disease ultimately resulting in end-stage arthrosis of the wrist. [ncbi.nlm.nih.gov]

Kienböck’s disease follows a specific progressive pattern through four stages. [concannonplasticsurgery.com]

As the disease progresses, surgical management is indicated. [thesportsphysiotherapist.com]

Keratoconus

Corneal Collagen Cross-Linking (CXL) is the only treatment that can actually halt the progression of the disease. [keratoconuscanada.org]

Keratoconus is a progressive eye disease, in which the normally round cornea thins and begins to bulge into a cone-like shape. [optilase.com]

Keratoconus is a non-inflammatory, progressive disease affecting the cornea. It causes progressive thinning of the cornea and bulging into a cone-like shape. [touchophthalmology.com]

Upper Motor Neuron Disease

However MND usually begins by affecting a single limb or aspect of motor function, becoming more generalised as the disease progresses. [mndnsw.asn.au]

In progressive bulbar palsy a disease of upper motor neurones, lower motor neurones or both? [brainscape.com]

A cervical collar worn in the early stages of disease has been shown to halt progress of the disease in some cases, as it prevents neck flexion. [orpha.net]