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231 Possible Causes for Progressive Intellectual Decline, Prominent Sulci

  • Alcohol Dementia

    The CT showed prominent sulci and gyri with deep white matter changes. There were no other abnormalities.[gponline.com]

  • Frontal Lobe Neoplasm

    A frontal lobe neoplasm might present with an array of symptoms that are collectively included in the "frontal lobe syndrome". Personality and abrupt emotional changes (aggression, apathy, impulsive behavior), and an overall decline of the functions for which the frontal lobe is crucial - planning, judgment, attention,[…][symptoma.com]

    Missing: Prominent Sulci
  • Cannabis Type Drug Dependence

    Ali Said Faqi, DVM, PhD, DABT, ATS, is a Senior Director of Developmental and Reproductive Toxicology, a Senior Principal Scientist at MPI Research and an Adjunct Associate Professor at Wayne State University, School of Medicine, Department of OBGYN in Detroit, MI. He received his Ph.D. from the University of Leipzig in[…][books.google.com]

    Missing: Prominent Sulci
  • Normal Pressure Hydrocephalus

    Definition (MSH) A form of compensated hydrocephalus characterized clinically by a slowly progressive gait disorder (see GAIT DISORDERS, NEUROLOGIC), progressive intellectual[fpnotebook.com] NPH is suggested when ventricular dilation is out of proportion to the prominence of the sulci, but this is a subjective call.[docneuro.com] […] gait disorder (see gait disorders, neurologic), progressive intellectual decline, and urinary incontinence.[icd10data.com]

  • Chediak Higashi Syndrome

    […] in the arms and legs (peripheral neuropathy), and a decline in intellectual functioning.[ghr.nlm.nih.gov] They do, however, have a significant risk of progressive neurological problems such as tremors, difficulty with movement and balance (ataxia), reduced sensation and weakness[ghr.nlm.nih.gov]

    Missing: Prominent Sulci
  • Pick Disease of The Brain

    intellectual decline (cognitive dysfunction/dementia) Sudden loss of muscle tone which may lead to falls (cataplexy) Tremors accompanying movement and, in some cases, seizures[npuk.org] Characteristic features include prominent cerebral sulci (i.e. cortical atrophy) and v entriculomegaly (i.e. central atrophy) without bulging of the third ventricular recesses[radiopaedia.org] Unsteadiness of gait, clumsiness, problems in walking (ataxia) Difficulty in posturing of limbs (dystonia) Slurred, irregular speech (dysarthria) Learning difficulties and progressive[npuk.org]

  • Aspartylglucosaminuria

    The hallmark of this lysosomal storage of oligosaccharides is progressive intellectual decline, markedly behavioral problems, hyperactivity, recurrent infections, epilepsy[ncbi.nlm.nih.gov] sulci Atrophy Normal 2 17.3 F Decreased Decreased Normal None Poor Atrophy Normal 3 26.6 F Decreased Decreased Mildly increased Several Poor Mild cerebral and cerebellar[docksci.com] This progressive decline continues until about age 25–28, when rapid impairment of abilities occurs, resulting in severe intellectual disability.[en.wikipedia.org]

  • Subacute Sclerosing Panencephalitis

    A gradual decline in intellectual abilities and behavioral alterations are followed by progressive myoclonus; muscle spasticity; seizures; dementia; autonomic dysfunction;[icd10data.com] They can range from hyperintensities in the parietal and occipital region, brain stem lesions, and marked atrophy, causing prominence of sulci.[cureus.com] Affected individuals present with poor school performance and progressive intellectual deterioration, personality changes and behavior abnormalities.[pubs.sciepub.com]

  • Unverricht-Lundborg Syndrome

    intellectual decline.[resourcerepository.org] […] with progressive neurologic and intellectual decline; age of onset between 8-13 years of age; autosomal recessive inheritance, caused by mutation in the cystatin B gene ([medical-dictionary.thefreedictionary.com] Cognitive decline, progressive Intellectual deterioration Progressive cognitive decline [ more ] 0001268 Myoclonus 0001336 Showing of 14 Last updated: 7/1/2019 Making a diagnosis[rarediseases.info.nih.gov]

    Missing: Prominent Sulci
  • Alzheimer Disease

    The intellectual decline is usually progressive, and initially spares the level of consciousness.[doi.org]

    Missing: Prominent Sulci

Further symptoms