JB disease first manifests as ataxia, progressive developmental milestone losses, epilepsy, and posterior vision losses in children of 2-4 years of age.
[scielo.br]
0001107 Seizures Seizure 0001250 Visual loss Loss of vision Vision loss [ more ] 0000572 30%-79% of people have these symptoms Abnormality of metabolism/homeostasis Laboratory
[rarediseases.info.nih.gov]
Results: Progressive vision loss was the initial symptom in 66.7% of patients and was isolated or associated with ataxia, epilepsy, and neurodevelopmental involution.
[scielo.br]