Progressive Loss of Vision & Rapidly Progressive to Persistent Vegetative State or Death: Causes & Reasons

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Patient File

Sex unknown, Age unknown

Reported Symptoms

Progressive Loss of Vision, Rapidly Progressive to Persistent Vegetative State or Death,

Negated

None

Unsure

None

Possible Causes

Neuronal Ceroid Lipofuscinosis

Most childhood forms of NCL are clinically characterized by progressive loss of vision as well as mental and motor deterioration, epileptic seizures, and premature death, [ncbi.nlm.nih.gov]

The juvenile form of neuronal ceroid lipofuscinosis (JNCL) is caused by mutations in the CLN3 gene, and is characterized by progressive loss of vision and development of motor [ncbi.nlm.nih.gov]

[…] motor impairment and loss of vision. [ncbi.nlm.nih.gov]

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Retinitis Pigmentosa

A 35-year-old man presented with history of painless, progressive loss of vision in the left eye for the past 7 years. [ncbi.nlm.nih.gov]

Her main complaints were night blindness and progressive loss of vision since the age of 9 years. [ncbi.nlm.nih.gov]

Retinitis pigmentosa (RP) is a highly heterogeneous group of disorders characterized by degeneration of the retinal photoreceptor cells and progressive loss of vision. [ncbi.nlm.nih.gov]

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Stargardt Macular Degeneration

Loss of photoreceptor cells leads to progressive vision loss in people with Stargardt macular degeneration. [ivami.com]

Progressive vision loss eventually leads to blindness in most cases. What Causes Stargardt's Disease? [allaboutvision.com]

Signs and Symptoms The most common symptom of Stargardt disease is the slow, progressive loss of vision in the center of the focal point of sight in both eyes. [news-medical.net]

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Usher Syndrome Type 1J

Usher Syndrome is rare inherited disorder that causes hearing loss and progressive vision loss. [raredr.com]

Usher syndrome is a genetic condition characterised by hearing loss or deafness, the progressive loss of vision and in some cases, vestibular dysfunction. [usherkidsaustralia.com]

Usher Syndrome is a genetic condition characterized by deafness at birth or progressive hearing loss and progressive vision loss. [usher1f.org]

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Macular Degeneration

Age Related Macular Degeneration is a degenerative disease of the retina that causes progressive loss of vision in the center of the eye. [enhancedvision.com]

Both cause progressive central vision loss with intact peripheral vision. [ncbi.nlm.nih.gov]

Early identification of higher risk patients may help prevent vision loss or slow down disease progression. [willseye.org]

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Usher Syndrome Type 1

Usher syndrome type 3 is characterized by post-lingual, progressive hearing loss, late-onset progressive vision loss due to retinitis pigmentosa and variable loss of vestibular [ltd.aruplab.com]

loss of vision due to retinitis pigmentosa. [nejm.org]

An autosomal recessive condition characterized by sensorineural hearing loss and progressive loss of vision due to retinitis pigmentosa. [medical-dictionary.thefreedictionary.com]

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Retinitis

A loss of side vision, or tunnel vision, is also common as RP progresses. [retinaspecialistsnw.com]

Retinitis pigmentosa (RP) describes a group of related diseases that tend to run in families and cause a slow but progressive loss of vision. [bostoneyegroup.com]

French biotech Horama has treated the first patients with a gene therapy for retinitis pigmentosa that could prevent the progressive loss of vision caused by this genetic [labiotech.eu]

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Usher Syndrome

Usher syndrome is a genetic disorder consisting of progressive loss of vision and hearing. [ncbi.nlm.nih.gov]

Progressive loss of vision due to retinitis pigmentosa begins in late childhood or adolescence. [sema4.com]

Some individuals perceive this as an additional loss of hearing, when it is actually the effect of the progressive loss of vision. [helenkeller.org]

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Usher Syndrome Type 1D

An autosomal recessive condition characterized by sensorineural hearing loss and progressive loss of vision due to retinitis pigmentosa. [medical-dictionary.thefreedictionary.com]

Progressive loss of vision due to retinitis pigmentosa begins in childhood. [sema4.com]

[…] type I cause sensorineural hearing loss, loss of vestibular function, and retinitis pigmentosa; three forms of type II and one form of type III are characterized by hearing loss [medical-dictionary.thefreedictionary.com]

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Usher Syndrome Type 2A

Progressive loss of vision due to retinitis pigmentosa begins in late childhood or adolescence. [sema4.com]

progresses to tunnel vision. [scholarsbank.uoregon.edu]

Retinitis pigmentosa first presents with night blindness, but progresses to tunnel vision and eventually blindness. [sema4.com]

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Common Cold

Age-related macular degeneration Researchers have suggested that both zinc and antioxidants delay the progression of age-related macular degeneration (AMD) and vision loss [ods.od.nih.gov]

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Retinitis pigmentosa 40

A loss of side vision, or tunnel vision, is also common as RP progresses. [bostonlaser.com]

A loss of side vision, or tunnel vision, also is common as RP progresses. [nweyes.com]

Year 1996 Retinitis pigmentosa (RP) refers to a group of related diseases that tend to run in families and cause slow but progressive loss of vision. [retinaldiagnostic.com]

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Usher Syndrome Type 1H

[…] from birth and progressive vision loss that begins in adolescence or adulthood. [ncbi.nlm.nih.gov]

Usher syndrome type II is characterized by hearing loss from birth and progressive vision loss that begins in adolescence or adulthood. [ghr.nlm.nih.gov]

Page 1 of 9 Usher syndrome Usher syndrome (USH) is characterized by hearing impairment, progressive vision loss due to retinitis pigmentosa (RP) and, in some cases, by vestibular [institut-vision.org]

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Urinary Tract Disease

A family history of chronic glomerular disease or impaired vision may stem from this syndrome, and men are more likely to progress to chronic renal failure and/or vision loss [healthywomen.org]

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Neuronal Ceroid Lipofuscinosis Type 3

Like the other neuronal ceroid-lipofuscinoses, it is characterized by progressive loss of vision, seizures, and loss of cognitive and motor functions, leading to premature [ingentaconnect.com]

The symptoms of juvenile CLN3 disease usually become apparent between 5 and 15 years of age when progressive loss of vision, seizures, and progressive neurological degeneration [rarediseases.org]

JNCL was suspected on the basis of characteristic symptoms including progressive loss of vision, seizures, mental retardation and motor disabilities. [link.springer.com]

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Alstrom Syndrome

Alstrom syndrome is characterized by a progressive loss of vision and hearing, a form of heart disease that enlarges and weakens the heart muscle (dilated cardiomyopathy), [secure.ssa.gov]

For more information, or to enroll in the trial click here: About Alström Syndrome Alström syndrome is characterized by a progressive loss of vision and hearing, a form of [raredr.com]

It is the result of a mutation in the ALMS1 gene, and symptoms often begin in childhood and commonly include a progressive loss of vision and hearing, obesity and heart disease [raredr.com]

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Infantile Neuroaxonal Dystrophy 1

loss of vision and of physical and mental skills. [onlymyhealth.com]

It affects axons, the part of a nerve cell that carries messages from the brain to other parts of the body, and causes progressive loss of vision, muscular control, and mental [secure.ssa.gov]

loss of vision and of physical and menta Quick Bites The symptoms of INAD get worse over time after beginning. [onlymyhealth.com]

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Usher Syndrome Type 3B

Usher syndrome is a genetic condition characterised by hearing loss or deafness, the progressive loss of vision and in some cases, vestibular dysfunction. [usherkidsaustralia.com]

RP causes night-blindness and a loss of peripheral vision (side vision) through the progressive degeneration of the retina. [news-medical.net]

People with Usher syndrome type III experience progressive hearing loss and vision loss beginning in the first few decades of life, according to Genetics Home Reference. [collive.com]

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Retinitis Pigmentosa Type 4

They are characterized by a gradual breakdown and degeneration of photoreceptor cells, which results in a progressive loss of vision. [eyecareinstitute.com]

Over time this causes photoreceptor cells to die and progressive loss of vision results. [retinaaustraliansw.com.au]

RP causes cells in the retina to die, causing progressive vision loss. The first sign of RP usually is night blindness. [jewishgeneticdiseases.org]

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Boucher-Neuhäuser Syndrome

Progressive loss of vision, dyschromatopsia, and photophobia are the primary ocular symptoms. Night blindness and constricted visual fields are noted by some patients. [disorders.eyes.arizona.edu]

At 12 years of age, he first noticed progressive loss of vision and photophobia in both eyes. The best-corrected visual acuity was 20/200 bilaterally. [synapse.koreamed.org]

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Pars Planitis

This form is more difficult to treat, and is often associated with progressive loss of vision. [bausch.com]

This may lead to blurred vision; dark, floating spots in the vision; and progressive vision loss. [xpertdox.com]

This may lead to blurred vision; dark, floating spots in the vision; and progressive vision loss.[1][2] Approximately 80% of cases are bilateral (affecting both eyes), although [rarediseases.info.nih.gov]

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Glaucoma

Glaucoma is a group of eye disorders characterized by damage to the optic nerve that leads to a progressive loss of peripheral vision that can culminate in blindness. [sylentis.com]

Treatment in glaucoma aims to lower intraocular pressure (IOP) to reduce the risk of progression and vision loss. [ncbi.nlm.nih.gov]

[…] and subsequent vision loss. 12-14 In particular, central corneal thickness has also been shown to be associated with disease progression in open-angle glaucoma, 15 which [web.archive.org]

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Autosomal Recessive Osteopetrosis Type 7

[…] visual loss Progressive loss of vision Progressive vision loss Progressive visual impairment Slowly progressive visual loss Vision loss, progressive Visual loss, progressive [rarediseases.info.nih.gov]

Nystagmus Involuntary, rapid, rhythmic eye movements 0000639 Optic atrophy 0000648 Optic nerve compression 0007807 Osteopetrosis Harder, denser, fracture-prone bones 0011002 Progressive [rarediseases.info.nih.gov]

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Retinitis Pigmentosa 7

Year 1996 Retinitis pigmentosa (RP) refers to a group of related diseases that tend to run in families and cause slow but progressive loss of vision. [retinaldiagnostic.com]

Retinitis pigmentosa is chronically debilitating due to progressive loss of vision. [ema.europa.eu]

This causes progressive peripheral vision loss, night blindness, central vision loss and, in some cases, blindness. [oaklandvision.com]

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Retinal Macular Dystrophy Type 2

It is characterised by macular degeneration that begins in childhood, adolescence or adulthood, resulting in progressive loss of vision. [2] [2] Signs and symptoms [ edit [en.wikipedia.org]

loss of vision. (10) If both parents carry the ABCA4 mutation, there’s a 25 percent chance that a child will have the condition since it is a recessive gene. (12) No cure [everydayhealth.com]

Retinitis pigmentosa (RP) is a group of hereditary retinal diseases, which are characterized by progressive loss of peripheral vision, and... [atlasrleye.com]

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Foster-Kennedy Syndrome

A 36-year-old man presented to the emergency department because of gradual blurring of vision in his right eye over 20 days and progressive loss of vision in the left eye [cmaj.ca]

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Neuronal Ceroid Lipofuscinosis Type 7

She had progressive motor and mental deterioration since the age of 2,5 years. Later she developed progressive vision loss, stereotypies, action myoclonus and epilepsy. [ncbi.nlm.nih.gov]

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Neuronal Ceroid Lipofuscinosis Type 10

JB disease first manifests as ataxia, progressive developmental milestone losses, epilepsy, and posterior vision losses in children of 2-4 years of age. [scielo.br]

Seizure 0001250 Visual loss Loss of vision Vision loss [ more ] 0000572 30%-79% of people have these symptoms Abnormality of metabolism/homeostasis Laboratory abnormality [rarediseases.info.nih.gov]

Results: Progressive vision loss was the initial symptom in 66.7% of patients and was isolated or associated with ataxia, epilepsy, and neurodevelopmental involution. [scielo.br]

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Malnutrition

Progressive loss of vision and hearing, as well as osteoarthritis, may limit mobility and affect the elderly people's ability to shop for food and prepare meals. [mna-elderly.com]

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Hypertension

Adequate control of blood pressure has been proven in randomised clinical trials to reduce vision loss associated with diabetic retinopathy. [ncbi.nlm.nih.gov]

vision loss Peripheral arterial disease causing leg pain with walking (claudication) Outpouchings of the aorta, called aneurysms About 1% of people with high blood pressure [emedicinehealth.com]

High blood pressure increases the risk of both development of diabetic retinopathy and its progression. [ncbi.nlm.nih.gov]

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