Progressive Loss of Visual Acuity: Causes & Reasons

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Possible Causes for Progressive Loss of Visual Acuity

Retinitis Pigmentosa

No trial reported a statistically significant benefit of vitamin supplementation on the progression of visual field loss or visual acuity loss. [cochrane.org]

Loss of or diminished night vision (the earliest & most frequent symptom) Normal visual acuity in early stages Donut shaped visual field loss progressing to severe constriction [mesvision.com]

Background Retinitis pigmentosa (RP) is the name given to a group of inherited eye disorders that cause a gradual, yet progressive, loss of vision. [cochrane.org]

Cone Rod Dystrophy Type 15

The diagnosis of cone dystrophy is suggested by progressive loss of visual acuity and color discrimination, often accompanied by hemeralopia (day blindness) and photophobia [aao.org]

loss of visual acuity leading to legal blindness in older adulthood.1 Advances in molecular genetics have led to the discovery of at least five genes associated with AD-CRD [bjo.bmj.com]

An initial loss of color vision and of visual acuity is followed by nyctalopia (night blindness) and loss of peripheral visual fields. [flybase.org]

Geographic Atrophy

Medical condition: Age-related Macular Degeneration (AMD) presents as a progressive loss of vision in the centre of the retina (the macula) resulting in a blurred area or [clinicaltrialsregister.eu]

[…] disease and loss of visual acuity. [cochranelibrary.com]

Association of 2-year progression along the AREDS AMD scale and development of late age-related macular degeneration or loss of visual acuity: AREDS Report 41. [pubmed.ncbi.nlm.nih.gov]

Retinitis pigmentosa 38

Nonsyndromic Retinitis Pigmentosa, Autosomal recessive retinitis pigmentosa, arRP, Nonsyndromic Retinitis Pigmentosa, Autosomal dominant retinitis pigmentosa, adRP Inheritance pattern Autosomal recessive, autosomal dominant Retinitis pigmentosa (RP) refers to a group of rare inherited diseases characterized by[…] [centogene.com]

Retinal Vasculopathy with Cerebral Leukodystrophy

NEW !Translate documents faster and better thanks to artificial intelligence! Translate Medical Documents Faster and Better thanks to Artificial Intelligence & Built-in Healthcare Terminology (Snomed-Ct, ICD-10) & Neural Machine Translation Translation of "small vessel diseases " (English → French) : TERMINOLOGY see[…] [wordscope.com]

Neuronal Ceroid Lipofuscinosis Type 10

The most frequent visual symptom was progressive visual acuity loss, reported by 10 (66.7%) patients. [scielo.br]

In our series, the most frequent presenting visual symptom was progressive visual acuity loss, a hallmark of NCL, in 10 (66.7%) patients 4 - 6. [scielo.br]

acuity; E= epilepsy; LVA= progressive loss of visual acuity; ATX= ataxia; NPMI= neuro-psycho-motor involution; ONA= optic nerve atrophy; XT= exotropia; JB= Jansky-Bielschowsky [scielo.br]

Cone Rod Dystrophy Type 10

[…] of visual acuity, progressive loss of color vision, progressive loss of peripheral vision more Clinical features from OMIM: 610283 Human phenotypes related to Cone-Rod Dystrophy [malacards.org]

Symptoms of cone dysfunction include loss of visual acuity, photophobia (light intolerance), and progressive color vision loss. [egl-eurofins.com]

Since childhood, the patient experienced reduced visual acuity, glare and, over the last ten years, progressive loss of visual acuity. [nature.com]

Goldmann-Favre Syndrome

A 21-year-old woman complained of progressive loss of visual acuity. She had also had night blindness since she was ten years old. [ncbi.nlm.nih.gov]

GFS manifests with progressive loss of visual acuity and night blindness. Peripheral vision can be decreased. Cataract is a frequent complication. [orpha.net]

Prognosis GFS has a progressive course. In most cases, visual loss occurs in the first two decades of life. [orpha.net]

Autosomal Dominant Optic Atrophy

Abstract Autosomal dominant optic atrophy (ADOA) is the most prevalent hereditary optic neuropathy resulting in progressive loss of visual acuity, centrocoecal scotoma and [ncbi.nlm.nih.gov]

This disorder presents in childhood with progressive loss of visual acuity that is usually bilateral, centrocecal scotoma that is typically symmetrical, and bilateral temporal [athenadiagnostics.com]

Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading [genecards.org]

Neuronal Ceroid Lipofuscinosis Type 8

The most frequent visual symptom was progressive visual acuity loss, reported by 10 (66.7%) patients. [scielo.br]

In our series, the most frequent presenting visual symptom was progressive visual acuity loss, a hallmark of NCL, in 10 (66.7%) patients 4 - 6. [scielo.br]

acuity; E= epilepsy; LVA= progressive loss of visual acuity; ATX= ataxia; NPMI= neuro-psycho-motor involution; ONA= optic nerve atrophy; XT= exotropia; JB= Jansky-Bielschowsky [scielo.br]

Boucher-Neuhäuser Syndrome

At 12 years of age, he first noticed progressive loss of vision and photophobia in both eyes. The best-corrected visual acuity was 20/200 bilaterally. [synapse.koreamed.org]

Progressive loss of vision, dyschromatopsia, and photophobia are the primary ocular symptoms. Night blindness and constricted visual fields are noted by some patients. [disorders.eyes.arizona.edu]

Foster-Kennedy Syndrome

A 52-year-old man had progressive loss of visual acuity in his left eye associated with anosmia of five years duration. [ncbi.nlm.nih.gov]

Case Presentation: In this study, we describe a 34-year-old male who presented with progressive loss of visual acuity and field. [sid.ir]

Gradual and progressive loss of vision is a hallmark of compressive optic neuropathy, the most common causes of which are meningioma, pituitary adenoma, intracranial aneurysm [ircmj.com]

Neuronal Ceroid Lipofuscinosis

He presented with progressive dementia, loss of visual acuity, gradual regression of speech and motor functions, and myoclonic jerks. [ncbi.nlm.nih.gov]

Most childhood forms of NCL are clinically characterized by progressive loss of vision as well as mental and motor deterioration, epileptic seizures, and premature death, [ncbi.nlm.nih.gov]

The juvenile form of neuronal ceroid lipofuscinosis (JNCL) is caused by mutations in the CLN3 gene, and is characterized by progressive loss of vision and development of motor [ncbi.nlm.nih.gov]

Autosomal Recessive Osteopetrosis Type 7

loss of vision Progressive vision loss Progressive visual impairment Slowly progressive visual loss Vision loss, progressive Visual loss, progressive [ more ] 0000529 Proptosis [rarediseases.info.nih.gov]

rhythmic eye movements 0000639 Optic atrophy 0000648 Optic nerve compression 0007807 Osteopetrosis Harder, denser, fracture-prone bones 0011002 Progressive visual loss Progressive [rarediseases.info.nih.gov]

Intermediate Uveitis

This form is more difficult to treat, and is often associated with progressive loss of vision. [bausch.com]

Optic Atrophy

Clinical features of ADOA include a slowly progressive bilateral loss of visual acuity, constriction of peripheral visual fields, central scotomas, and color vision abnormalities [ncbi.nlm.nih.gov]

Retinitis pigmentosa 18

The visual prognosis for children with Bardet-Biedl syndrome is poor, progressive loss of visual acuity arised early in the first decade of life. REFERENCES 1. [scielo.br]

Retinitis Pigmentosa 13

The visual prognosis for children with Bardet-Biedl syndrome is poor, progressive loss of visual acuity arised early in the first decade of life. REFERENCES 1. [scielo.br]

Optic Atrophy Type 2

loss of visual acuity, significant optic nerve pallor and occasionally additional neurological manifestations, with females being unaffected. [orpha.net]

Results: Both affected subjects had poor vision from birth and complained of progressive visual loss over time. Current visual acuity ranged from 6/60 to 6/120. [molvis.org]

[…] definition Early-onset X-linked optic atrophy is a rare form of hereditary optic atrophy, seen in only 4 families to date, with an onset in early childhood, characterized by progressive [orpha.net]

Bardet-Biedl Syndrome Type 8

The visual prognosis for children with Bardet-Biedl syndrome is poor, progressive loss of visual acuity arised early in the first decade of life. REFERENCES 1. [scielo.br]

Autosomal Dominant Optic Atrophy - Hearing Loss - Peripheral Neuropathy Syndrome

Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading [cloud-clone.com]

Autosomal dominant optic atrophy (ADOA) is characterized by progressive visual loss beginning in childhood, loss of visual acuity, and optic nerve pallor. [egl-eurofins.com]

Jalili Syndrome

Cone-rod dystrophies are a heterogeneous group of genetically related retinal diseases characterized by progressive loss of visual acuity and achromatopsia [5]. [clinmedjournals.org]

loss of vision with advancing age. [findzebra.com]

V.9 had photophobia and nystagmus from early infancy with progressive visual impairment detected as moderate visual loss in early childhood progressed to severe visual loss [nature.com]

Macular Dystrophy with Central Cone Involvement

The diagnosis of cone dystrophy is suggested by progressive loss of visual acuity and color discrimination, often accompanied by hemeralopia (day blindness) and photophobia [aao.org]

Patients have night blindness and show progressive peripheral visual field loss over 3-5 decades. Most patients maintain good visual acuity. [quizlet.com]

loss of central visual acuity and peripheral visual dysfunction. [atlasrleye.com]

Late-Adult Onset Retinitis Pigmentosa

Case 3 A 56-year-old man presented with complaints of progressive loss of visual acuity and peripheral field for the past 6 months. [ncbi.nlm.nih.gov]

[…] with slower progression of visual dysfunction. [ncbi.nlm.nih.gov]

She also noted slowly progressive peripheral field loss. [ncbi.nlm.nih.gov]

Choroideremia

[…] vision and a loss of visual acuity later in life. [invitae.com]

[…] characterized by progressive loss of the visual field, with visual acuity remaining close to normal levels until the very late stages of disease. [nejm.org]

[…] scotomas to concentric visual field loss. [orpha.net]

Cancer-Associated Retinopathy

A 70-year-old woman developed progressive visual loss with compromised visual acuity and visual fields, cells in the anterior chamber and vitreous, attenuated retinal arterioles [ncbi.nlm.nih.gov]

Acuity; Visual Fields Abstract A 70-year-old woman developed progressive visual loss with compromised visual acuity and visual fields, cells in the anterior chamber and vitreous [collections.lib.utah.edu]

The patient developed progressive visual dysfunction including bilateral visual acuity loss and concentric constriction of visual fields. [ncbi.nlm.nih.gov]

CAPOS Syndrome

Lastly, at age 12 she presented progressive loss of visual acuity, associated with bilateral optic atrophy. [elsevier.es]

Cone Rod Dystrophy Type 5

Since childhood, the patient experienced reduced visual acuity, glare and, over the last ten years, progressive loss of visual acuity. [nature.com]

followed by progressive loss in peripheral vision and night blindness. [centogene.com]

Decreased visual acuity and loss of color vision occurred after the age of 20 years, followed by progressive atrophy of the central 5° to 10°. [jamanetwork.com]

Acute Zonal Occult Outer Retinopathy

acuity and 21 systemic corticosteroid-treated eyes with progressive visual acuity loss. [ncbi.nlm.nih.gov]

[…] with progressive visual acuity loss. [ncbi.nlm.nih.gov]

Over her 13-year follow-up, best-corrected visual acuity dropped to 20/60 in both eyes and visual field loss because of chorioretinal atrophy progressed significantly. [ncbi.nlm.nih.gov]

Retinal Degeneration-Nanophthalmos-Glaucoma Syndrome

loss of visual acuity, significant optic nerve pallor and occasionally additional neurological manifestations, with females being unaffected. [mendelian.co]

We report a case of a 60–year–old female who presented with bilateral slowly progressive visual loss. [semanticscholar.org]

Decreased acuity Reduced night vision Progressive central field loss Loss of color vision Loss of detail Peripheral fields can be affected May need visual efficiency training [tsbvi.edu]