Progressive Loss of Visual Acuity: Causes & Reasons

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Possible Causes for Progressive Loss of Visual Acuity

Retinitis Pigmentosa

No trial reported a statistically significant benefit of vitamin supplementation on the progression of visual field loss or visual acuity loss. [ncbi.nlm.nih.gov]

Background Retinitis pigmentosa (RP) is the name given to a group of inherited eye disorders that cause a gradual, yet progressive, loss of vision. [cochrane.org]

Loss of or diminished night vision (the earliest & most frequent symptom) Normal visual acuity in early stages Donut shaped visual field loss progressing to severe constriction [mesvision.com]

Cone Rod Dystrophy Type 15

The diagnosis of cone dystrophy is suggested by progressive loss of visual acuity and color discrimination, often accompanied by hemeralopia (day blindness) and photophobia [aao.org]

loss of visual acuity leading to legal blindness in older adulthood.1 Advances in molecular genetics have led to the discovery of at least five genes associated with AD-CRD [bjo.bmj.com]

An initial loss of color vision and of visual acuity is followed by nyctalopia (night blindness) and loss of peripheral visual fields. [flybase.org]

Neuronal Ceroid Lipofuscinosis Type 10

The most frequent visual symptom was progressive visual acuity loss, reported by 10 (66.7%) patients. [scielo.br]

In our series, the most frequent presenting visual symptom was progressive visual acuity loss, a hallmark of NCL, in 10 (66.7%) patients44 Rider JA, Rider DL. [scielo.br]

In our series, the most frequent presenting visual symptom was progressive visual acuity loss, a hallmark of NCL, in 10 (66.7%) patients 4 - 6. [scielo.br]

Neuronal Ceroid Lipofuscinosis Type 8

The most frequent visual symptom was progressive visual acuity loss, reported by 10 (66.7%) patients. [scielo.br]

In our series, the most frequent presenting visual symptom was progressive visual acuity loss, a hallmark of NCL, in 10 (66.7%) patients44 Rider JA, Rider DL. [scielo.br]

In our series, the most frequent presenting visual symptom was progressive visual acuity loss, a hallmark of NCL, in 10 (66.7%) patients 4 - 6. [scielo.br]

Cone Rod Dystrophy Type 10

[…] of visual acuity, progressive loss of color vision, progressive loss of peripheral vision more Clinical features from OMIM: 610283 Human phenotypes related to Cone-Rod Dystrophy [malacards.org]

Symptoms of cone dysfunction include loss of visual acuity, photophobia (light intolerance), and progressive color vision loss. [egl-eurofins.com]

acuity Retinal degeneration Progressive visual loss Pica Retinal dystrophy Visual impairment Autosomal dominant inheritance Ranula Macular atrophy Scotoma Abnormal retinal [mendelian.co]

Boucher-Neuhäuser Syndrome

with involvement of the choriocapillaris, retinal pigment epithelium, and outer retina, resulting in loss of visual acuity with a dense ring scotoma and a spared central [accessanesthesiology.mhmedical.com]

At 12 years of age, he first noticed progressive loss of vision and photophobia in both eyes. The best-corrected visual acuity was 20/200 bilaterally. [synapse.koreamed.org]

Clinical history and examination to evaluate the progression of the condition. No specific anesthetic considerations. [accessanesthesiology.mhmedical.com]

Neuronal Ceroid Lipofuscinosis

He presented with progressive dementia, loss of visual acuity, gradual regression of speech and motor functions, and myoclonic jerks. [ncbi.nlm.nih.gov]

Most childhood forms of NCL are clinically characterized by progressive loss of vision as well as mental and motor deterioration, epileptic seizures, and premature death, [ncbi.nlm.nih.gov]

The juvenile form of neuronal ceroid lipofuscinosis (JNCL) is caused by mutations in the CLN3 gene, and is characterized by progressive loss of vision and development of motor [ncbi.nlm.nih.gov]

Geographic Atrophy

Association of 2-year progression along the AREDS AMD scale and development of late age-related macular degeneration or loss of visual acuity: AREDS Report 41. [pubmed.ncbi.nlm.nih.gov]

[…] disease and loss of visual acuity. [cochranelibrary.com]

Disease Burden of GA GA is associated with considerable disease progression and burden, with patients experiencing a loss of both visual acuity and independence when performing [karger.com]

Intermediate Uveitis

This form is more difficult to treat, and is often associated with progressive loss of vision. [bausch.com]

Autosomal Recessive Osteopetrosis Type 7

loss of vision Progressive vision loss Progressive visual impairment Slowly progressive visual loss Vision loss, progressive Visual loss, progressive [ more ] 0000529 Proptosis [rarediseases.info.nih.gov]

rhythmic eye movements 0000639 Optic atrophy 0000648 Optic nerve compression 0007807 Osteopetrosis Harder, denser, fracture-prone bones 0011002 Progressive visual loss Progressive [rarediseases.info.nih.gov]

Goldmann-Favre Syndrome

A 21-year-old woman complained of progressive loss of visual acuity. She had also had night blindness since she was ten years old. [ncbi.nlm.nih.gov]

GFS manifests with progressive loss of visual acuity and night blindness. Peripheral vision can be decreased. Cataract is a frequent complication. [orpha.net]

Prognosis GFS has a progressive course. In most cases, visual loss occurs in the first two decades of life. [orpha.net]

Autosomal Dominant Optic Atrophy

Abstract Autosomal dominant optic atrophy (ADOA) is the most prevalent hereditary optic neuropathy resulting in progressive loss of visual acuity, centrocoecal scotoma and [ncbi.nlm.nih.gov]

This disorder presents in childhood with progressive loss of visual acuity that is usually bilateral, centrocecal scotoma that is typically symmetrical, and bilateral temporal [athenadiagnostics.com]

The affected family members exhibited early-onset and progressive visual impairment, resulting in mild to profound loss of visual acuity. [ncbi.nlm.nih.gov]

CAPOS Syndrome

Lastly, at age 12 she presented progressive loss of visual acuity, associated with bilateral optic atrophy. [elsevier.es]

Neuronal Ceroid Lipofuscinosis Type 2

[…] changes in visual acuity with eventual visual loss, the onset of seizures, loss of cognitive and motor function, and premature death. [2] The diagnosis is based on the characteristic [saudija.org]

(ANCL, Kufs disease). [2] Despite differences in the age of onset and the exact enzymatic process involved, the NCL share similar phenotypic expression including rapidly progressive [saudija.org]

Retinitis pigmentosa 38

1) Jacobson SG, Cideciyan AV. Treatment possibilities for retinitis pigmentosa. New Engl. J. Med. 2010;363,1669-71 2) Hartong DT, Berson EL, Dryia TP. Retinitis pigmentosa. The Lancet 2006;368(9549):1795-809 3) Rivolta C, Sharon D, DeAngelis MM et Al.. Retinitis pigmentosa and allied diseases: numerous diseases, genes, and[…] [malattierare.regione.veneto.it]

Retinal Vasculopathy with Cerebral Leukodystrophy

NEW !Translate documents faster and better thanks to artificial intelligence! Translate Medical Documents Faster and Better thanks to Artificial Intelligence & Built-in Healthcare Terminology (Snomed-Ct, ICD-10) & Neural Machine Translation Translation of "small vessel diseases " (English → French) : TERMINOLOGY see[…] [wordscope.com]

Retinitis Pigmentosa 13

The visual prognosis for children with Bardet-Biedl syndrome is poor, progressive loss of visual acuity arised early in the first decade of life. REFERENCES 1. [scielo.br]

Retinitis pigmentosa 18

The visual prognosis for children with Bardet-Biedl syndrome is poor, progressive loss of visual acuity arised early in the first decade of life. REFERENCES 1. [scielo.br]

Optic Atrophy Type 2

loss of visual acuity, significant optic nerve pallor and occasionally additional neurological manifestations, with females being unaffected. [orpha.net]

Results: Both affected subjects had poor vision from birth and complained of progressive visual loss over time. Current visual acuity ranged from 6/60 to 6/120. [molvis.org]

[…] definition Early-onset X-linked optic atrophy is a rare form of hereditary optic atrophy, seen in only 4 families to date, with an onset in early childhood, characterized by progressive [orpha.net]

Congenital Neuronal Ceroid Lipofuscinosis

New Mutation Found in Newborn with Congenital Neuronal Ceroid Lipofuscinosis, Case Study Reports A new mutation was identified in a baby girl with congenital neuronal ceroid lipofuscinosis (CLN10), a rare disease that belongs to the heterogeneous group of neuronal ceroid lipofuscinoses (NCL), also known as Batten[…] [battendiseasenews.com]

Neuronal Ceroid Lipofuscinosis Type 7

The neuronal ceroid lipofuscinoses are a group of neurodegenerative, lysosomal storage disorders. They are inherited as an autosomal recessive pattern with the exception of adult neuronal ceroid lipofuscinosis, which can be inherited in either an autosomal recessive or an autosomal dominant manner. The neuronal[…] [ncbi.nlm.nih.gov]

Mitochondrial Membrane Protein-Associated Neurodegeneration

Neurodegeneration with brain iron accumulation (NBIA) refers to an inherited heterogeneous group of disorders pathologically characterized by focal brain iron deposition. Clinical phenotype, imaging findings and genotype are variable among the different types of this disorder. In this case report, we describe the[…] [ncbi.nlm.nih.gov]

Autosomal Dominant Optic Atrophy - Hearing Loss - Peripheral Neuropathy Syndrome

Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading [cloud-clone.com]

Autosomal dominant optic atrophy (ADOA) is characterized by progressive visual loss beginning in childhood, loss of visual acuity, and optic nerve pallor. [egl-eurofins.com]

Cone Rod Dystrophy Type 16

visual loss Reduced visual acuity Rod-cone dystrophy Abnormality of the nervous system Photophobia Etiology Chiu N, Lee W, Liu PK, Levi SR, Wang HH, Chen N, Kang EY, Seo [ncbi.nlm.nih.gov]

Initial symptoms of cone dysfunction include early and progressive loss of central visual acuity, photophobia and defects in color vision2. [nature.com]

followed by progressive loss in peripheral vision and night blindness. [centogene.com]

Bardet-Biedl Syndrome Type 8

The visual prognosis for children with Bardet-Biedl syndrome is poor, progressive loss of visual acuity arised early in the first decade of life. REFERENCES 1. [scielo.br]

Optic Atrophy

Clinical features of ADOA include a slowly progressive bilateral loss of visual acuity, constriction of peripheral visual fields, central scotomas, and color vision abnormalities [ncbi.nlm.nih.gov]

Bardet-Biedl Syndrome Type 6

The visual prognosis for children with Bardet-Biedl syndrome is poor, progressive loss of visual acuity arised early in the first decade of life. [scielo.br]

Macular Dystrophy with Central Cone Involvement

The diagnosis of cone dystrophy is suggested by progressive loss of visual acuity and color discrimination, often accompanied by hemeralopia (day blindness) and photophobia [aao.org]

loss of central visual acuity and peripheral visual dysfunction. [atlasrleye.com]

Patients have night blindness and show progressive peripheral visual field loss over 3-5 decades. Most patients maintain good visual acuity. [quizlet.com]

Foster-Kennedy Syndrome

A 52-year-old man had progressive loss of visual acuity in his left eye associated with anosmia of five years duration. [ncbi.nlm.nih.gov]

Case Presentation: In this study, we describe a 34-year-old male who presented with progressive loss of visual acuity and field. [sid.ir]

Gradual and progressive loss of vision is a hallmark of compressive optic neuropathy, the most common causes of which are meningioma, pituitary adenoma, intracranial aneurysm [ircmj.com]

Acute Zonal Occult Outer Retinopathy

acuity and 21 systemic corticosteroid-treated eyes with progressive visual acuity loss. [ncbi.nlm.nih.gov]

[…] with progressive visual acuity loss. [ncbi.nlm.nih.gov]

Over her 13-year follow-up, best-corrected visual acuity dropped to 20/60 in both eyes and visual field loss because of chorioretinal atrophy progressed significantly. [ncbi.nlm.nih.gov]