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4,964 Possible Causes for Progressive or Intermittent Jaundice, Reticulocytes Increased, Thrombocytopenia

  • HELLP Syndrome

    Despite delivery of the fetus, her condition deteriorated over 3-4 days with high-grade fever, worsening thrombocytopenia and anaemia requiring transfusion support.[ncbi.nlm.nih.gov] […] risk in preeclampsia Counts of 3 meet HELLP criterion Blood smear – evaluate for evidence of microangiopathic hemolysis Helmet cells Burr cells Schistocytes Reticulocyte[arupconsult.com] This might contribute to thrombocytopenia and thrombotic microangiopathy.[ncbi.nlm.nih.gov]

    Missing: Progressive or Intermittent Jaundice
  • Leukoerythroblastic Anemia

    Acute Erythroblastic Leukemia Anemia, X-Linked, without Thrombocytopenia aplastic anemia Aplastic Anemia, Idiopathic Bone Marrow Failure Syndromes chronic myeloid leukemia[rgd.mcw.edu] An increased absolute number of reticulocytes indicates increased marrow erythropoiesis. u. Rouleaux: red cells in stacks, as coins.[kerrybrandis.com] […] who presented seven years following apparently successful surgery and adjuvant chemo-radio-therapy, with blood film findings of microangiopathic hemolytic anemia (MAHA), thrombocytopenia[ncbi.nlm.nih.gov]

    Missing: Progressive or Intermittent Jaundice
  • Primary Myelofibrosis

    Six weeks later, he developed grade 4 thrombocytopenia and grade 3 anemia.[ncbi.nlm.nih.gov] The percentage of reticulocytes is mildly increased but may vary widely in a given case.[patient-help.com] The main adverse effects of ruxolitinib are anemia and thrombocytopenia.[merck.com]

    Missing: Progressive or Intermittent Jaundice
  • Paroxysmal Nocturnal Hemoglobinuria

    The combination of thrombosis, splenomegaly, and thrombocytopenia (TST) is challenging because anticoagulants are indicated but thrombocytopenia may increase the bleeding[ncbi.nlm.nih.gov] Erythrocytes fractionated by centrifugation revealed increased glycolytic enzyme activities of hexokinase, G3PD, PGK, TPI, PK, LDH, G6PD, and 6PGD in the reticulocyte-rich[pediatrics.aappublications.org] This case raises caution for heparin-induced thrombocytopenia in paroxysmal nocturnal hemoglobinuria.[ncbi.nlm.nih.gov]

    Missing: Progressive or Intermittent Jaundice
  • Thrombotic Thrombocytopenic Purpura

    Unfortunately, there is no clear guidance for when thrombocytopenia is refractory for a prolonged period of time.[ncbi.nlm.nih.gov] reticulocytes Haemolysis Screen reduced haptoglobins increased LDH (this is the most sensitive marker of severity and disease activity) unconjugated hyperbilirubinaemia increased[lifeinthefastlane.com] Careful analysis revealed the development of heparin-induced thrombocytopenia (HIT) that precluded platelet count (PLT) normalization.[ncbi.nlm.nih.gov]

    Missing: Progressive or Intermittent Jaundice
  • Gaucher Disease

    KEYWORDS: GBA gene mutation; Gaucher cells; thrombocytopenia; type 1 Gaucher disease[ncbi.nlm.nih.gov] Gaucher disease is a common inborn error of metabolism leading to widespread chronic inflammation and often thrombocytopenia.[ncbi.nlm.nih.gov] Type 1 Gaucher disease At onset, patients with type 1 Gaucher disease commonly present with painless splenomegaly, anemia, or thrombocytopenia.[emedicine.medscape.com]

    Missing: Progressive or Intermittent Jaundice
  • Fetal Erythroblastosis

    Schistocytes, as a sign of disseminated intravascular coagulation and burr cells, are present, as well as neutropenia and thrombocytopenia.[symptoma.com] Management of severe alloimmune thrombocytopenia in the newborn. Arch Dis Child Fetal Neonatal Ed 2000 ; 82 : F173 –5. Ohlsson A, Lacy JB.[doi.org] Peripheral blood morphology shows increased reticulocytes. Erythroblasts (also known as nucleated red blood cells) occur in moderate and severe disease.[moondragon.org]

    Missing: Progressive or Intermittent Jaundice
  • Sickle Cell Disease

    Patients should be monitored for leukopenia and thrombocytopenia. Complications from long-term usage are not yet known. Efficacy in children has not been proven.[symptoma.com] With each course, fetal reticulocytes increased within 48-72 h, peaked in 7-11 d, and fell by 18-21 d.[doi.org] Hydroxyurea is a leukemogen and causes neutropenia and thrombocytopenia. It is also a teratogen and should not be given to females of child-bearing age.[msdmanuals.com]

    Missing: Progressive or Intermittent Jaundice
  • Familial Myelofibrosis

    Blood counts generally reveal normocytic, normochromic anemia, leukopenia, and thrombocytopenia.[symptoma.com] , thrombocytosis, increased LDH Prognostic factors Histologic stage at diagnosis (prefibrotic versus fibrotic) Adverse factors include age 70 years, anemia (Hb 10 g/dL), thrombocytopenia[pathologyoutlines.com] Responses were also reported for anaemia (22%) and thrombocytopenia (50%).[onlinelibrary.wiley.com]

    Missing: Progressive or Intermittent Jaundice
  • Chronic Myeloid Leukemia

    Immune thrombocytopenia (ITP) was also diagnosed in this patient following the detection of antiplatelet autoantibodies.[ncbi.nlm.nih.gov] […] by imatinib, it was intriguing to analyze the role of platelet-derived growth factor receptor-α in relation to imatinib treatment in the development of imatinib-induced thrombocytopenia[ncbi.nlm.nih.gov] […] hemorrhage should be considered as a possible complication in patients with atypical chronic myeloid leukemia, even in chronic phase, if they have hyperleukocytosis and thrombocytopenia[ncbi.nlm.nih.gov]

    Missing: Progressive or Intermittent Jaundice

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