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277 Possible Causes for Progressive Polyneuropathy, Pruritus

  • Diabetes Mellitus

    […] outweighed by the benefits of reducing cardiovascular risk. [ 8 ] Presentation Patients with all types of diabetes may present with polyuria, polydipsia, lethargy, boils, pruritus[patient.info] Symptoms develop 30 min to 2 h after injection and include urticaria, angioedema, pruritus, bronchospasm, and anaphylaxis.[msdmanuals.com] They can produce immediate pain or burning followed by erythema, pruritus, and induration—the latter sometimes persisting for days.[web.archive.org]

  • Paraneoplastic Syndrome

    We report a fatal case of severe chronic progressive axonal polyradiculoneuropathy in association with this antibody.[doi.org] This 59-year-old man developed ophthalmoplegia, dysarthria, dysphagia, pruritus, ataxia, corticobulbar and corticospinal signs in association with prostate cancer.[ncbi.nlm.nih.gov] It is usually a distal sensorimotor polyneuropathy that causes mild motor weakness, sensory loss, and absent distal reflexes.[merckmanuals.com]

  • Multiple Myeloma

    […] to multiple myeloma The initial presentation occasionally is a polyneuropathy when it is part of a POEMS syndrome (mostly the sclerotic form).[radiopaedia.org] Her pruritus resolved, but the lesions persisted. Footnotes Competing interests: None declared. This article has been peer reviewed.[cmaj.ca] Trial-ineligibility was determined by presence of at least one of the common exclusion criteria: heart/renal failure, liver/renal diseases, polyneuropathy, HIV positivity.[ncbi.nlm.nih.gov]

  • Waldenstrom Macroglobulinemia

    Neuropathy is typically slowly progressive, distal, symmetrical, and sensorimotor.[emedicine.medscape.com] POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes) also may be associated with Waldenström macroglobulinemia.[emedicine.medscape.com]

  • Chronic Alcoholism

    Generalised pruritus Generalised skin itching ( pruritus ) may occur due to the build up of poorly metabolised substances that stimulate nerve endings in the skin.[dermnetnz.org] Patients may present with jaundice, pruritus, abnormal laboratory findings (eg, thrombocytopenia, hypoalbuminemia, coagulopathy), or complications of portal hypertension,[clevelandclinicmeded.com]

  • Vasculitis

    The lesions may be asymptomatic or associated with burning, pruritus, or pain.[clinicaladvisor.com] Neuropathy Sensory or Sensory-Motor General patterns Mononeuritis multiplex (13%) Asymmetric polyneuropathy (85%) Distal symmetric polyneuropathy (2%) More slowly progressive[neuromuscular.wustl.edu] The main symptom in urticaria is the presence of intense pruritus, UV lesions may present with a more burning sensation [ 2 ].[intechopen.com]

  • Anxiety Disorder

    The neurological signs are often a progressive spastic paraparesis, cerebellar ataxia, polyneuropathy, and cognitive impairment.[ncbi.nlm.nih.gov]

  • Diabetic Polyneuropathy

    Ms Q is a 52-year-old woman who has had progressive polyneuropathy in the setting of diabetes for the past 8 years.[ncbi.nlm.nih.gov] […] urinary tract infection, urinary frequency or dribbling, erectile dysfunction, loss of libido, dyspareunia, vaginal dryness, anorgasmia Sudomotor (sweat glands) symptoms: pruritus[aafp.org] […] extremities and by flaccid paralysis. progressive hypertrophic polyneuropathy Déjérine-Sottas disease.[medical-dictionary.thefreedictionary.com]

  • Chronic Inflammatory Demyelinating Polyneuropathy

    Shortly after HSCT the patient developed progressive polyneuropathy of the lower legs and hypoesthesia. Five months later a severe dementia followed.[ncbi.nlm.nih.gov] […] were local reactions (ie, swelling, redness, heat, pain, and itching at the injection site), headache, diarrhea, fatigue, back pain, nausea, extremity pain, cough, rash, pruritus[prnewswire.com] We report a 58-year-old woman with DADS that progressed to a severe case of classic CIDP.[ncbi.nlm.nih.gov]

  • Systemic Scleroderma

    […] due to systemic sclerosis Progressive systemic sclerosis Scleredema Scleredema buschkes Scleroderma Scleroderma induced by chemical, including drugs Scleroderma of lung Scleroderma[icd9data.com] The steroids help with the pruritus and may lead to some lesional thinning.[clinicaladvisor.com] For pruritus, camphor and menthol as well as PUVA light treatment may be used.[aocd.org]

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