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71 Possible Causes for Progressive Polyneuropathy, Vertigo, Vitiligo

  • Pernicious Anemia

    The case presented here is a woman who had a restoration of fertility after initiation of vitamin B12 treatment for vitiligo-associated pernicious anemia.[ncbi.nlm.nih.gov] Vertigo The inability to cope with heights and wide open spaces.[pernicious-anaemia-society.org] Vitiligo is an acquired disease characterized by depigmentation of the skin due to destruction of melanocytes.[ncbi.nlm.nih.gov]

  • Multiple Myeloma

    In addition, patients having Addison disease may present other manifestations of autoimmune endocrinopathies, such as hypoparathyroidism, pernicious anemia, and vitiligo.[pediatrics.aappublications.org] […] to multiple myeloma The initial presentation occasionally is a polyneuropathy when it is part of a POEMS syndrome (mostly the sclerotic form).[radiopaedia.org] Sludging in the capillaries can result in purpura, retinal hemorrhage, papilledema, coronary ischemia, or central nervous system (CNS) symptoms (eg, confusion, vertigo, seizure[emedicine.medscape.com]

  • Vitamin B12 Deficiency

    peripheral neuropathy, and spinal degeneration.[ncbi.nlm.nih.gov] Skin Lesions, Vitiligo, And Sore Tongue Any change in the B12 content in the body can lead to skin problems like vitiligo, dermatitis, hyperpigmentation, or acne.[curejoy.com] Dizziness Frequent bouts of dizziness or vertigo can often be a signal that your B12 stores are low.[activebeat.com]

  • Paraneoplastic Syndrome

    […] disease that occur with type 1 diabetes such as Graves' disease, Hashimoto's thyroiditis, hypothyroidism, pernicious anemia, premature ovarian failure, Addison's disease and vitiligo[clinlabnavigator.com] We report a fatal case of severe chronic progressive axonal polyradiculoneuropathy in association with this antibody.[doi.org] BACKGROUND: 69 year old gentleman who presented with persistent and intractable vertigo for over a year.[neurology.org]

  • Adrenal Insufficiency

    […] situation may be associated with symptoms suggestive of chronic adrenal insufficiency such as hyperpigmentation, salt craving, and association with autoimmune diseases such as vitiligo[ncbi.nlm.nih.gov] Adrenomyeloneuropathy begins in adolescence or early adulthood with weakness, spasticity, and distal polyneuropathy but is milder and progresses more slowly.[clinicaladvisor.com] Other symptoms include vertigo, hypotension, depression, salt craving, and vitiligo (depigmented patches of skin).[pharmacytimes.com]

  • Diabetes Mellitus

    A case of acute-onset type 1 diabetes mellitus concomitant with pneumonitis and vitiligo is described. 2017 The Authors.[ncbi.nlm.nih.gov] In addition, using multiple drugs may increase the risk of falls owing to the occurrence of drowsiness, muscle weakness, balance change, vertigo and hypotension [ 31 ].[doi.org] Spritz, Early-onset autoimmune vitiligo associated with an enhancer variant haplotype that upregulates class II HLA expression, Nature Communications, 10.1038/s41467-019-08337[doi.org]

  • Vasculitis

    Neuropathy Sensory or Sensory-Motor General patterns Mononeuritis multiplex (13%) Asymmetric polyneuropathy (85%) Distal symmetric polyneuropathy (2%) More slowly progressive[neuromuscular.wustl.edu] Causes of Vasculitis (Case Report) A rare association of localized scleroderma (LS) type morphea, vitiligo, autoimmune hypothyroidism, pneumonitis, autoimmune thrombocytopenic[sclero.org] Giant cell arteritis: a new association with benign paroxysmal positional vertigo. Laryngoscope, 114 (2004), pp. 1420-1425 [10] C. Saieh, J. Arce, M. Contreras, E.[elsevier.es]

  • Heavy Metal Poisoning

    In addition, non-inflammatory degenerative disease of the sensorimotor nerves (sensorimotor polyneuropathy) may advance to progressive deterioration (atrophy).[rarediseases.org] Similarly mercury poisoning can cause Vitiligo, headaches, depression, eczema, chronic fatigue, and hair loss as the sulfur in the hair binds the mercury.[drmanik.net] Confusion Joint Pain Prostate Cancer Constipation Kidney Failure Speech Impairment Convulsion Liver Disease Testicular Atrophy Deafness Low IQ Tinnitus Dementia Lung Cancer Vertigo[vitalityandwellness.com.au]

  • Stiff-Person Syndrome

    Multifocal motor neuropathy (MMN) is an uncommon immune-mediated, slowly progressive, purely motor neuropathy that is characterised by the presence of multifocal conduction[doi.org] It is frequently associated with other autoimmune diseases such as diabetes, thyroiditis, vitiligo, and pernicious anemia.[ninds.nih.gov] […] gain and fatigue, worsening with tension or stress that also occurred in periods without vertigo.[ncbi.nlm.nih.gov]

  • Diabetes Mellitus Type 2

    […] peripheral nerves Epidemiology : Diabetic polyneuropathy is the most common form of polyneuropathy in Western countries.[amboss.com] These patients are also prone to other autoimmune disorders such as Graves' disease, Hashimoto's thyroiditis, Addison's disease, vitiligo, celiac sprue, autoimmune hepatitis[doi.org] Clinical features Early: progressive symmetric loss of sensation in the distal lower extremities A "stocking-glove" sensory loss pattern with proximal progression is typical[amboss.com]

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