Proliferation: Causes & Reasons

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Possible Causes for Proliferation

Psoriatic Arthritis

The hallmark of PsA is the combination of erosive change with bone proliferation, in a predominantly distal distribution (e.g. interphalangeal more than metacarpophalangeal [radiopaedia.org]

Costimulatory inhibitors (i.e. abatacept and belatacept) effectively abrogate T lymphocyte activation and proliferation and have been shown to be effective for disease control [ncbi.nlm.nih.gov]

[…] and marginal bone erosions; " pencil-in-cup " deformities are common, but not pathognomonic for PsA 3 joint subluxation or interphalangeal ankylosis may be present. bone proliferation [radiopaedia.org]

Exostosis

Distal phalanx of great toe Treatment Simple excision, may recur, particularly with incomplete excision Does not transform Microscopic (histologic) description Spindle cell proliferation [pathologyoutlines.com]

[…] histologic) images Moderately cellular cartilage Reactive bone Molecular / cytogenetics description Differential diagnosis Osteochondroma: different location, no spindle cell proliferation [pathologyoutlines.com]

Florid reactive periostitis is characterized by a loose myxomatous spindle cell proliferation with minimal osteocartilaginous proliferation. 6,10 Bizarre parosteal osteochondromatous [healio.com]

Fibroma

Histological features showed hyperkeratosis, hyperplasia of epidermis, proliferation of fibroblasts and hyaline degeneration in partial hyperplastic collagen. [ncbi.nlm.nih.gov]

JTOF features a proliferation of cellular fibroblastic tissue admixed with woven bone trabeculae with varying histologic presentations. [ncbi.nlm.nih.gov]

MICROSCOPIC DETAILS Histological sections reveal squamous mucosa with a partially ulcerated spindle cell proliferation. [acupath.com]

Epulis

Myofibroblasts play fundamental roles in pathologic conditions, even by activation and proliferation or by deletion. [ncbi.nlm.nih.gov]

Immunohistochemical analysis of the lesion was performed and the rate of cell proliferation was determined by immunostaining with Ki-67 and PCNA, which showed labeling indexes [ncbi.nlm.nih.gov]

It shows a proliferation of multinucleated giant cells in a background of stroma of plump ovoid or spindle cells. [webpathology.com]

Tumor Lysis Syndrome

Tumor lysis syndrome typically occurs in aggressive, rapidly proliferating lymphoproliferative disorders. [icd9data.com]

In chronic lymphocytic leukemia (CLL), historically, TLS has been observed less often, owing to a low proliferation rate and slow response to chemotherapy. [ncbi.nlm.nih.gov]

Initiating chemotherapy in bulky, rapidly proliferating tumors causes rapid cell turnover that in turn releases metabolites into circulation that give rise to metabolic derangements [ncbi.nlm.nih.gov]

Proliferating Angioendotheliomatosis

Proliferating angioendotheliomatosis Specialty Oncology Proliferating angioendotheliomatosis has historically been divided into two groups, (1) a reactive, involuting type [en.wikipedia.org]

proliferating angioendotheliomatosis 解釋增生性血管內皮瘤病 proliferating : 一再繁殖 angioendotheliomatosis : 血管內皮瘤病 ※英文詞彙 proliferating angioendotheliomatosis 在字典百科英英字典中的解釋。 [dict.site]

Immunohistological identification of the proliferating cell type made diagnosis of intravascular B-cell lymphoma possible in paraffin-embedded biopsies. [unboundmedicine.com]

Malignant Angioendotheliomatosis

Conversely, RAE was typified by a cytologically-bland intravascular proliferation, with actin-positive, perivascular, pericytic cuffs. [ncbi.nlm.nih.gov]

Citation metadata Article Preview : Intravascular lymphomatosis is a rare lymphoma characterized by proliferation of malignant cells within the lumen of small blood vessels [go.gale.com]

Reactive angioendotheliomatosis is a rare cutaneous vascular proliferation characterized by intravascular hyperplasia of endothelial cells and tuft-like proliferation of vessels [histopathology-india.net]

Peripheral Vasoproliferative Retinopathy

|On examination - retinal vascular proliferation (disorder)|Peripapillary choroidal neovascular membrane|Peripapillary choroidal neovascular membrane (disorder)|Peripheral [averbis.com]

[…] photocoagulation. 6, 27 More recent papers reported similar favorable surgical results for severe diabetic fibrovascular proliferations. [clinicalgate.com]

Histologically, the removed tissue showed mild vascular proliferation with mild inﬂammatory inﬁltrates, ﬁbrin deposits, and glial cell proliferation. [docksci.com]

Carcinoma of the Prostate

In florid BCH, the proliferation index is intermediate between ordinary BCH and basal cell carcinoma. [ncbi.nlm.nih.gov]

Of the borderline intraductal proliferations, 52% (11/21) showed PTEN loss and 27% (4/15) expressed ERG. [ncbi.nlm.nih.gov]

Cytoplasmic PTEN loss was identified in 84% (38/45) of the intraductal carcinoma and 100% (15/15) of intraductal cribriform proliferation cases. [ncbi.nlm.nih.gov]

Epithelial Ovarian Cancer

Cell proliferation and invasion were monitored by MTT assay and transwell invasion assay. [ncbi.nlm.nih.gov]

Additionally, reintroduction of miR‑320 expression suppressed cell proliferation and invasion in EOC. [ncbi.nlm.nih.gov]

The results showed that TAM CM accelerated the proliferation and migration of ID8 cells. [ncbi.nlm.nih.gov]

Paget Disease of the Breast

Two cases of pigmented mammary Paget disease and all cases of pigmented epidermotropic metastatic breast carcinoma showed the proliferation of dendritic melanocytes arranged [ncbi.nlm.nih.gov]

Malignant epithelial (Paget) cells infiltrate and proliferate in the epidermis, causing thickening of the nipple and the areolar skin. [emedicine.medscape.com]

[…] melanocytic chemotactic factor by neoplastic cells of the mammary carcinoma when they reach the dermoepidermal junction has been postulated as the cause of the melanocytic proliferation [ncbi.nlm.nih.gov]

CDK4-Linked Melanoma

We showed that a target of p21, CDK2, was necessary for proliferation in CDK4/6i-treated cells. [stm.sciencemag.org]

The R24P variant impairs proliferation of U20S cells. [cancerres.aacrjournals.org]

It takes two treatments to tango Inhibitors of cyclin-dependent kinases 4 and 6, proteins involved in cell proliferation, have shown promising results in breast cancer, but [stm.sciencemag.org]

Acanthosis Nigricans

Cardiovascular Congenital generalized lipodystrophy type 1, congenital generalized lipodystrophy type 2 Chemical / poisoning No underlying causes Dermatologic Peroxisome proliferator-activated [wikidoc.org]

On histological examination of the mass, keratin proliferation and epidermal papilloma were observed. [ncbi.nlm.nih.gov]

A, familial partial lipodystrophy type 2, hyperthyroidism, insulin receptor defect, metabolic syndrome, polycystic ovary syndrome, Rabson-Mendenhall syndrome, peroxisome proliferator-activated [wikidoc.org]

Skin Neoplasm

Proliferating Tricholemmal Tumor Proliferating tricholemmal tumor (PTT), also known as proliferating pilar tumor or pilar tumor, is a well-circumscribed proliferation of squamous [hindawi.com]

A variety of benign lesions involve proliferation of melanocytes, including dysplastic nevi, compound nevi, and intradermal nevi. [consultant360.com]

An elastogram (left) and ultrasound image (right) showing a benign cystic proliferation. Figure 14. An elastogram showing a benign cystic proliferation. Figure 15. [radiologyinfo.org]

Plasmablastic Lymphoma

Abstract Plasmablastic lymphoma (PBL) is a unique type of diffuse proliferation of large neoplastic lymphoid cells most of which resemble B immunoblasts, but all tumor cells [ncbi.nlm.nih.gov]

The histological examination of the specimen showed a diffuse proliferation of round- to oval-shaped large cells with scant cytoplasm, and prominent nucleoli. [ncbi.nlm.nih.gov]

The tumor consisted of a monotonous proliferation of undifferentiated large cells with relatively abundant cytoplasm, eccentrically located round nuclei with prominent nucleoli [ncbi.nlm.nih.gov]

Lipid Cell Tumor of the Ovary

[…] of steroid hormone-producing cells: stromal luteoma, luteinized granulosa cell tumor (usually juvenile), fibroma-thecoma, stromal Leydig cell tumor and proliferations at [pathologyoutlines.com]

Functioning ovarian tumors with peripheral steroid cell proliferation. A report of twenty-four cases. Int J Gynecol Pathol. 1986;5:319–337. [humpath.com]

[…] actin (30%) Electron microscopy description Increased smooth endoplasmic reticulum, mitochondria have tubulovesicular cristae Differential diagnosis Tumors with secondary proliferation [pathologyoutlines.com]

Breast Adenoma

Tubular adenoma of the breast is characterized histologically by a circumscribed mass consisting of prominent lobular proliferation and closely packed small ducts with minimal [link.springer.com]

The epithelial proliferation appears in a single terminal ductal unit and describes duct-like spaces surrounded by a fibroblastic stroma. [pathologyatlas.ro]

Definition / general Benign biphasic tumor composed of a proliferation of both glandular epithelial and stromal components of the terminal duct lobular unit Essential features [pathologyoutlines.com]

Glomerulonephritis

"Proliferative" - due to proliferation of endothelial cells and mesangial cells. [pathologyatlas.ro]

Leukocyte proliferation is indicated by the presence of neutrophils and monocytes within the glomerular capillary lumen and often accompanies cellular proliferation. [emedicine.medscape.com]

Almost all glomeruli are enlarged (hypercellular) due to proliferation of endothelial cells and mesangial cells, swelling of endothelial cells and inflammatory infiltrate [pathologyatlas.ro]

Pleomorphic Xanthoastrocytoma

Anaplastic PXAs were microscopically characterized by monotonous proliferation of atypical cells, increased mitotic activity, necrosis and microvascular proliferation. [ncbi.nlm.nih.gov]

A primitive glial proliferation was found, and paraffin-embedded tumor tissue obtained by biopsy confirmed the diagnosis of anaplastic PXA. [ncbi.nlm.nih.gov]

[…] markedly elevated Ki-67 proliferation index. [ncbi.nlm.nih.gov]

Fibrillary Astrocytoma

Endothelial proliferation and necrosis are lacking. [advancedradteaching.com]

Nuclear atypia is a diagnostic criterion but mitotic activity, necrosis and microvascular proliferation are absent. [monarchinitiative.org]

No necrosis if present, would be GBM Dense cellularity Mitotic figures Vascular proliferation Necrosis is present Prognosis High incidence of progression to glioblastoma [pedsoncologyeducation.com]

Atrophic Vaginitis

In the group treated twice weekly, 2 out of the 31 patients who completed the study showed weak proliferation of the endometrium. [ncbi.nlm.nih.gov]

Estrogen also induces epithelial proliferation and maintains adequate elastin/collagen content in these tissues. [medscape.com]

Fewer patients who were using the vaginal tablets experienced endometrial proliferation or hyperplasia compared with patients who were using the vaginal cream. [ncbi.nlm.nih.gov]

Kimura Disease

[…] and later a lymphocyte proliferation. [doi.org]

[…] with e·o·sin·o·phil·i·a solitary or multiple small benign cutaneous erythematous nodules, occurring mainly on the head and neck in young adults, characterized by dermal proliferation [medical-dictionary.thefreedictionary.com]

Lymphoid proliferation and eosinophilic infiltration are common to both. [mjdrdypu.org]

Breast Fibroadenolipoma

This characteristic difference between the mammographic and sonographic findings was attributed to the hamartoma compressibility, and was associated with the over-proliferation [ncbi.nlm.nih.gov]

It results from a benign proliferation of fibrous, glandular, and fatty tissue (hence fibro-adeno-lipoma) surrounded by a thin capsule of connective tissue. [sumerdoc.blogspot.com]

There also proliferated smooth muscle spindle cells with eosinophilic cytoplasm embedded in loose myxoid stroma. [hindawi.com]

Pleuropulmonary Blastoma

We hypothesize that loss of DICER1 in the epithelium of the developing lung alters the regulation of diffusible factors that promote mesenchymal proliferation. [ncbi.nlm.nih.gov]

Further, they indicate that clonal proliferation in pleuropulmonary blastoma is restricted to the malignant mesenchymal elements, supporting the notion that the epithelial [ncbi.nlm.nih.gov]

Both may show benign epithelium-lined cysts and mesenchymal proliferation, often with skeletal muscle differentiation. [ncbi.nlm.nih.gov]

Autoimmune Gastritis

RESULTS: A proportion (25%) of the CD4(+) clones from the gastric corpus of AIG patients proliferated in response to porcine H(+),K(+)-ATPase. [ncbi.nlm.nih.gov]

T cell proliferation induced by phorbol myristate acetate was normal. [ncbi.nlm.nih.gov]

[…] typical parameters for this type of gastritis, such as grade of the periglandular lymphocytic infiltration, grade of glandular destruction and incidence of nodular ECL cell proliferates [ncbi.nlm.nih.gov]

Gynecomastia

Pubertal gynecomastia is the glandular proliferation of male breast tissue. [ncbi.nlm.nih.gov]

It should be differentiated from pseudogynecomastia, which is characterized by fat deposition without glandular proliferation and from breast carcinoma. [ncbi.nlm.nih.gov]

Gynecomastia refers to enlargement of male breast (s) due to benign proliferation of glandular tissue and is caused by excessive estrogen. [ncbi.nlm.nih.gov]

Fibrosarcoma

From Wikidata Jump to navigation Jump to search connective tissue cancer that has material basis in fibrous connective tissue and characterized by the presence of immature proliferating [wikidata.org]

Description Also known as English fibrosarcoma connective tissue cancer that has material basis in fibrous connective tissue and characterized by the presence of immature proliferating [wikidata.org]

Pulmonary Capillary Hemangiomatosis

It is characterized histologically by exuberant proliferation of capillaries that often invade alveolar septae, bronchial walls, and pleura. [ncbi.nlm.nih.gov]

Proliferated capillaries were surrounded by fine collagen and α-smooth muscle actin-positive myofibroblasts. [ncbi.nlm.nih.gov]

We describe the first cases of familial pulmonary capillary hemangiomatosis, a disorder in which capillaries in the lungs proliferate. [ncbi.nlm.nih.gov]

Tufted Angioma

Four children affected by intradermal vascular proliferations are presented. [ncbi.nlm.nih.gov]

Histopathologically, it is characterized by proliferation of closely packed capillaries in the dermis in a 'cannonball' distribution. [ncbi.nlm.nih.gov]

Tufted angioma is a benign vascular proliferation which presents most commonly in infants and children and could occasionally be complicated by Kasabach-Merritt syndrome. [ncbi.nlm.nih.gov]

Spindle Cell Hemangioma

BACKGROUND: Spindle cell hemangioma is a benign vascular proliferation that usually occurs on acral sites. [ncbi.nlm.nih.gov]

The tumor was a well-circumscribed vascular proliferation of spindled to epithelioid endothelial cells. [ncbi.nlm.nih.gov]

Spindle cell hemangioma is a rare benign tumor characterized by cavernous blood vessels and spindle cell proliferation. [ncbi.nlm.nih.gov]