Proliferation: Causes & Reasons

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Possible Causes for Proliferation

Psoriatic Arthritis

The hallmark of PsA is the combination of erosive change with bone proliferation, in a predominantly distal distribution (e.g. interphalangeal more than metacarpophalangeal [radiopaedia.org]

Costimulatory inhibitors (i.e. abatacept and belatacept) effectively abrogate T lymphocyte activation and proliferation and have been shown to be effective for disease control [ncbi.nlm.nih.gov]

[…] and marginal bone erosions; " pencil-in-cup " deformities are common, but not pathognomonic for PsA 3 joint subluxation or interphalangeal ankylosis may be present. bone proliferation [radiopaedia.org]

Proliferating Angioendotheliomatosis

Proliferating angioendotheliomatosis Specialty Oncology Proliferating angioendotheliomatosis has historically been divided into two groups, (1) a reactive, involuting type [en.wikipedia.org]

proliferating angioendotheliomatosis 解釋增生性血管內皮瘤病 proliferating : 一再繁殖 angioendotheliomatosis : 血管內皮瘤病 ※英文詞彙 proliferating angioendotheliomatosis 在字典百科英英字典中的解釋。 [dict.site]

[…] review of Reversing Proliferating Angioendotheliomatosis: As God Intended The Raw Vegan Plant-Based Detoxification & Regeneration Workbook for Healing Patients. [goodreads.com]

Malignant Angioendotheliomatosis

Proliferating angioendotheliomatosis Specialty Oncology Proliferating angioendotheliomatosis has historically been divided into two groups, (1) a reactive, involuting type [en.wikipedia.org]

Proliferating Systematized Angioendotheliomatosis. [jamanetwork.com]

Conversely, RAE was typified by a cytologically-bland intravascular proliferation, with actin-positive, perivascular, pericytic cuffs. [ncbi.nlm.nih.gov]

Peripheral Vasoproliferative Retinopathy

|On examination - retinal vascular proliferation (disorder)|Peripapillary choroidal neovascular membrane|Peripapillary choroidal neovascular membrane (disorder)|Peripheral [averbis.com]

[…] photocoagulation. 6, 27 More recent papers reported similar favorable surgical results for severe diabetic fibrovascular proliferations. [clinicalgate.com]

Histologically, the removed tissue showed mild vascular proliferation with mild inﬂammatory inﬁltrates, ﬁbrin deposits, and glial cell proliferation. [docksci.com]

Plasmablastic Lymphoma

Abstract Plasmablastic lymphoma (PBL) is a unique type of diffuse proliferation of large neoplastic lymphoid cells most of which resemble B immunoblasts, but all tumor cells [ncbi.nlm.nih.gov]

The histological examination of the specimen showed a diffuse proliferation of round- to oval-shaped large cells with scant cytoplasm, and prominent nucleoli. [ncbi.nlm.nih.gov]

The tumor consisted of a monotonous proliferation of undifferentiated large cells with relatively abundant cytoplasm, eccentrically located round nuclei with prominent nucleoli [ncbi.nlm.nih.gov]

Epulis

Immunohistochemical analysis of the lesion was performed and the rate of cell proliferation was determined by immunostaining with Ki-67 and PCNA, which showed labeling indexes [ncbi.nlm.nih.gov]

Myofibroblasts play fundamental roles in pathologic conditions, even by activation and proliferation or by deletion. [ncbi.nlm.nih.gov]

It shows a proliferation of multinucleated giant cells in a background of stroma of plump ovoid or spindle cells. [webpathology.com]

Tumor Lysis Syndrome

Tumor lysis syndrome typically occurs in aggressive, rapidly proliferating lymphoproliferative disorders. [icd9data.com]

In chronic lymphocytic leukemia (CLL), historically, TLS has been observed less often, owing to a low proliferation rate and slow response to chemotherapy. [ncbi.nlm.nih.gov]

Initiating chemotherapy in bulky, rapidly proliferating tumors causes rapid cell turnover that in turn releases metabolites into circulation that give rise to metabolic derangements [ncbi.nlm.nih.gov]

Epithelial Ovarian Cancer

Our findings imply that EIF5A1 is a vital regulator of EOC proliferation and progression and is a potential prognostic marker and therapeutic target in EOC. [ncbi.nlm.nih.gov]

The results showed that TAM CM accelerated the proliferation and migration of ID8 cells. [ncbi.nlm.nih.gov]

Additionally, reintroduction of miR‑320 expression suppressed cell proliferation and invasion in EOC. [ncbi.nlm.nih.gov]

Kimura Disease

[…] and later a lymphocyte proliferation. [doi.org]

[…] with e·o·sin·o·phil·i·a solitary or multiple small benign cutaneous erythematous nodules, occurring mainly on the head and neck in young adults, characterized by dermal proliferation [medical-dictionary.thefreedictionary.com]

Lymphoid proliferation and eosinophilic infiltration are common to both. [mjdrdypu.org]

Pulmonary Capillary Hemangiomatosis

It is characterized histologically by exuberant proliferation of capillaries that often invade alveolar septae, bronchial walls, and pleura. [ncbi.nlm.nih.gov]

Proliferated capillaries were surrounded by fine collagen and α-smooth muscle actin-positive myofibroblasts. [ncbi.nlm.nih.gov]

We describe the first cases of familial pulmonary capillary hemangiomatosis, a disorder in which capillaries in the lungs proliferate. [ncbi.nlm.nih.gov]

Tufted Angioma

Histopathologic and immunohistochemical findings excluded Kaposi's sarcoma and bacillary angiomatosis, the two vascular proliferations most frequently seen in the immunocompromised [ncbi.nlm.nih.gov]

Four children affected by intradermal vascular proliferations are presented. [ncbi.nlm.nih.gov]

Histopathologically, it is characterized by proliferation of closely packed capillaries in the dermis in a 'cannonball' distribution. [ncbi.nlm.nih.gov]

Spindle Cell Hemangioma

BACKGROUND: Spindle cell hemangioma is a benign vascular proliferation that usually occurs on acral sites. [ncbi.nlm.nih.gov]

The tumor was a well-circumscribed vascular proliferation of spindled to epithelioid endothelial cells. [ncbi.nlm.nih.gov]

Spindle cell hemangioma is a rare benign tumor characterized by cavernous blood vessels and spindle cell proliferation. [ncbi.nlm.nih.gov]

Hemangiomatosis

Biopsy of the cutaneous lesions revealed a polypoidal proliferation of vessels consistent with cherry hemangiomata. [ncbi.nlm.nih.gov]

Definition / general Proliferation of benign appearing capillaries in alveolar septa that appear to compress pulmonary veins May represent a secondary angioproliferative process [pathologyoutlines.com]

However, the identification of proliferating and invasive capillaries, which are unique to PCH, led to the correct diagnosis. [mayoclinic.pure.elsevier.com]

Proliferating Trichilemmal Cyst

“Proliferating epithelial cysts. Clinicopathologic analysis of 96 cases”. J Cutan Pathol. vol. 22. 1995. pp. 394-406. [dermatologyadvisor.com]

A spectrum was observed from trichilemmal cyst with minimal hyperplasia, to full-blown proliferating trichilemmal cyst. [ncbi.nlm.nih.gov]

To report a case of proliferating trichilemmal cyst in a 55-year-old woman. Observational case report. [ncbi.nlm.nih.gov]

CDK4-Linked Melanoma

We examined correlation between p53 expression and cell proliferation, and its role in the pathogenesis of keratinocyte skin tumors. [semanticscholar.org]

We showed that a target of p21, CDK2, was necessary for proliferation in CDK4/6i-treated cells. [stm.sciencemag.org]

@article{Rakocevic2018InterplayBT, title={Interplay Between the Immunohistochemical Expression of P53 and the Proliferation Index in the Keratinocyte Tumors of the Skin}, [semanticscholar.org]

Hemangioma

Propranolol suppressed cell proliferation of HemECs by arresting cell progression at G0/G1 phase. [ncbi.nlm.nih.gov]

RESULTS AND CONCLUSION: We found that curcumin potently inhibited proliferation in HemECs, achieving low-micromolar IC50 (the half maximal inhibitory concentration) value. [ncbi.nlm.nih.gov]

Infantile hemangiomas are benign vascular tumors characterized by the proliferation of the endothelial cells. 1 These lesions are rarely present at birth, but appear within [hemangeol.com]

Breast Adenoma

Tubular adenoma of the breast is characterized histologically by a circumscribed mass consisting of prominent lobular proliferation and closely packed small ducts with minimal [link.springer.com]

The epithelial proliferation appears in a single terminal ductal unit and describes duct-like spaces surrounded by a fibroblastic stroma. [pathologyatlas.ro]

Definition / general Benign biphasic tumor composed of a proliferation of both glandular epithelial and stromal components of the terminal duct lobular unit Essential features [pathologyoutlines.com]

Rapidly Involuting Congenital Hemangioma

Congenital hemangiomas (CH) are benign vascular neoplasms that proliferate in utero and have completed development by birth. [ncbi.nlm.nih.gov]

Infantile hemangiomas are not present at birth, go on to proliferate and then involute, whereas congenital hemangiomas are mature at birth. [ncbi.nlm.nih.gov]

The distinctive morphology and behavior suggests that these tumors undergo a life cycle of proliferation and involution during fetal life. [ncbi.nlm.nih.gov]

Ductal Carcinoma in Situ

We report a rare case of low-grade intraductal carcinoma with tumor-associated lymphoid proliferation (TALP) in the parotid gland of a 75-year-old woman. [ncbi.nlm.nih.gov]

Epithelium and Fibroadenoma 71 Degenerative Metaplastic and Sarcomatous Changes in Proliferating Intralobular Connective Tissue 75 References 77 Lesions of the Ductal System [books.google.com]

A noninvasive (noninfiltrating) carcinoma of the breast characterized by a proliferation of malignant epithelial cells confined to the mammary ducts or lobules, without light-microscopy [profiles.umassmed.edu]

Blue Nevus

The blue nevus is a well-described benign melanocytic proliferation that generally occurs on the skin. Infrequently, blue nevi are found on mucosal surfaces. [ncbi.nlm.nih.gov]

They represent benign proliferations of fusiform dermal melanocytes in the submucosa or deep dermis. These cells contain abundant melanin granules. [ncbi.nlm.nih.gov]

Histopathological, dermal and subcutaneous proliferations of pigmented melanocytes with melanophages were detected. [ncbi.nlm.nih.gov]

Lymphangioleiomyomatosis

LAM cells reactive for proliferating-cell nuclear antigen (PCNA), a marker of cellular proliferation, were spindle-shaped, in contrast to the large, epithelioid cells reacting [doi.org]

Reduction in proliferation was also seen in human angiomyolipoma-derived cells. [ncbi.nlm.nih.gov]

Although interferon (IFN)-γ inhibited proliferation of HBFs, IFN-γ treatment had little effect on proliferation of LAMD and TSC2-null cells. [doi.org]

Non-Involuting Congenital Hemangioma

B13 Vascular Proliferation 363 Lymphatic Malformations 369 Bizarreshaped Vessel Vascular Tumors 377 B14 Spindle Cell Proliferation 384 B15 Round Cell Proliferation 409 Round [books.google.it]

Vascular proliferation is also noted around sweat glands. [histopathology-india.net]

The tumor is formed from the proliferation of the endothelial cells. [infantilehemangioma.com]

Fibrillary Astrocytoma

Endothelial proliferation and necrosis are lacking. [advancedradteaching.com]

Nuclear atypia is a diagnostic criterion but mitotic activity, necrosis and microvascular proliferation are absent. [monarchinitiative.org]

No necrosis if present, would be GBM Dense cellularity Mitotic figures Vascular proliferation Necrosis is present Prognosis High incidence of progression to glioblastoma [pedsoncologyeducation.com]

Angiocentric Glioma

Necrosis and vascular proliferation were not observed and mitoses were sparse or absent. MIB-1 proliferation indices ranged from [ncbi.nlm.nih.gov]

AGs characteristically exhibit mixed features of ependymal and diffuse astrocytic differentiation and low proliferation rates, with Ki-67 labeling indices ranging from less [ncbi.nlm.nih.gov]

Necrosis and vascular proliferation were not observed and mitoses were sparse or absent. MIB-1 proliferation indices ranged from PTPRJ ) gene. [doi.org]

Astroblastoma

Because of its high degree of proliferation, the presence of astroblastic pseudorosettes, prominent perivascular hyalinization, regional hyaline changes, and pushing borders [ncbi.nlm.nih.gov]

Assessment of proliferation and ploidy indices in further cases may provide important prognostic data for this poorly understood entity. [ncbi.nlm.nih.gov]

[…] the perivascular pseudorosette pattern with broad, non-tapering processes radiating towards a central vessel without anaplastic features such as necrosis and endothelial proliferation [ncbi.nlm.nih.gov]

Pleomorphic Xanthoastrocytoma

Anaplastic PXAs were microscopically characterized by monotonous proliferation of atypical cells, increased mitotic activity, necrosis and microvascular proliferation. [ncbi.nlm.nih.gov]

A primitive glial proliferation was found, and paraffin-embedded tumor tissue obtained by biopsy confirmed the diagnosis of anaplastic PXA. [ncbi.nlm.nih.gov]

[…] markedly elevated Ki-67 proliferation index. [ncbi.nlm.nih.gov]

Gynecomastia

Pubertal gynecomastia is the glandular proliferation of male breast tissue. [ncbi.nlm.nih.gov]

It should be differentiated from pseudogynecomastia, which is characterized by fat deposition without glandular proliferation and from breast carcinoma. [ncbi.nlm.nih.gov]

Gynecomastia refers to enlargement of male breast (s) due to benign proliferation of glandular tissue and is caused by excessive estrogen. [ncbi.nlm.nih.gov]

Pigmented Villonodular Synovitis

By means of magnetic resonance imaging, synovial proliferation may be depicted directly. [symptoma.com]

This indicates that implantation of the prosthesis might have caused the lesion or might have caused its proliferation. [ncbi.nlm.nih.gov]

Pigmented villonodular synovitis (PVNS) is a rare benign neoplastic proliferation of synovial tissue which is typically localised and usually responds well to surgery and/ [ncbi.nlm.nih.gov]

Vulvar Hemangioma

Cutaneous vascular proliferations. Part II. Hyperplasias and benign neoplasms. J Am Acad Dermatol 1997;37:887–919. 2. Patrice SJ, Wiss K, Mulliken JB. [kundoc.com]

Fig. 2 This figure shows a proliferation of tortuous vessels in the submucosa, with variation in size. [scielo.br]

Cutaneous vascular proliferations. Part II. Hyperplasias and benign neoplasms. J Am Acad Dermatol 1997 ; 37 : 887 –919. ↵ Patrice SJ, Wiss K, Mulliken JB. [sti.bmj.com]

Endometrial Hyperplasia

The aim of this study was to establish whether the expression of proliferation regulatory proteins in the endometria of patients having PCOS, with or without hyperplasia, [ncbi.nlm.nih.gov]

This growth is much more than the normal proliferation of the endometrium during menstrual periods. [symptoma.com]

In CEH, no or limited cyclic patterns of proliferation, apoptosis, Bcl-2 and Bax were found. Increased proliferation rates coincided with deregulated apoptosis. [ncbi.nlm.nih.gov]