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51 Possible Causes for Prominent Corneal Nerves

  • Multiple Endocrine Neoplasia Type 2B

    We studied a two-generation family with an inherited syndrome of prominent corneal nerves and lesions of the tongue resembling neuromas without the characteristic neoplasms[ncbi.nlm.nih.gov] Ocular findings included ptosis secondary to thickening of the lid margins, subconjunctival and perilimbal neuromas, and prominent corneal nerves extending up to the pupillary[ncbi.nlm.nih.gov] All patients had prominent corneal nerves, thickened eyelids, mild ptosis and eversion of the upper eyelids.[ncbi.nlm.nih.gov]

  • Familial Medullary Thyroid Carcinoma

    Although characteristic of MEN 2B, prominent corneal nerves have been noted in subjects with MEN 2A.[jmg.bmj.com] The proband (III.1) was found to have prominent corneal nerves on routine ophthalmological examination in his late 30s.[jmg.bmj.com] Familial medullary thyroid carcinoma and prominent corneal nerves associated with the germline V804M and V778I mutations on the same allele of RET Lidia Kasprzak a , Serge[jmg.bmj.com]

  • Multiple Endocrine Neoplasia Type 4

    prominent corneal nerves of grade 2 or higher.[link.springer.com] Prominent corneal nerves: a novel sign of lipoid proteinosis. Br J Ophthalmol. 2012 Jul;96(7):935-40 Kriszt Á, Losonczy G, Berta A, Takács L.[webeye.ophth.uiowa.edu] Kinoshita, S., Tanaka, F., Ohashi, Y., Ikeda, M., Takai, S.: Incidence of prominent corneal nerves in multiple endocrine neoplasia type 2A. Am. J.[link.springer.com]

  • Lipoid Proteinosis

    Prominent corneal nerves were detected in all patients regardless of age and were more apparent in patients with more severe genetic mutations.[ncbi.nlm.nih.gov] CONCLUSION: Prominent corneal nerves can be helpful in the early diagnosis of LP and should be added to the list of LP ophthalmological diagnostic features.[ncbi.nlm.nih.gov]

  • Familial Congenital Nasolacrimal Duct Obstruction

    Prominent corneal nerves were detected in all patients regardless of age and were more apparent in patients with more severe genetic mutations.[bjo.bmj.com] Prominent corneal nerves: a novel sign of lipoid proteinosis Yasser H Al-Faky 1 , Thomas M Bosley 1 , Turki Al-Turki 2 , Mustafa A M Salih 3 , Khaled K Abu-Amero 1 , Adel[bjo.bmj.com] Conclusion Prominent corneal nerves can be helpful in the early diagnosis of LP and should be added to the list of LP ophthalmological diagnostic features.[bjo.bmj.com]

  • Cataract

    Her ocular findings included corneal clouding, colobomas of the iris and optic nerve, and posterior subcapsular cataracts.[ncbi.nlm.nih.gov] She had a triangular facies, a prominent forehead, proptosis, a small nose, and a small jaw.[ncbi.nlm.nih.gov]

  • Corneal Stromal Dystrophy

    corneal nerves (nerves won't show up in retroillumination ) -manifests later in life than L1 Lattice 3 and 3A Dystrophy -stromal lattice amyloid deposits are fewer and thicker[studyblue.com] […] stromal deposits: bilateral facial palsy ( protruding lips, skin laxity, "hound dog" ) cranial and peripheral neuropathy -cardiac and renal failure -lattice may look like prominent[studyblue.com]

  • Keratoconus

    RESULTS: Corneal protrusion, scissoring reflex, corneal thinning, Fleischer's ring, and prominent nerve fibres were the most prevalent findings in the keratoconic corneas[ncbi.nlm.nih.gov] Do the prominent corneal nerves seen by slit-lamp biomicroscopy anatomically represent either a response or a contribution to the viscious eye rubbing cycle we see clinically[reviewofophthalmology.com] […] well as any additional KC signs such as prominent nerve fibres, scissoring reflex and Charleaux 'oil droplet' sign on retinoscopy.[ncbi.nlm.nih.gov]

  • Multiple Endocrine Neoplasia

    Ocular findings included ptosis secondary to thickening of the lid margins, subconjunctival and perilimbal neuromas, and prominent corneal nerves extending up to the pupillary[ncbi.nlm.nih.gov] Prominent corneal nerves: a novel sign of lipoid proteinosis. Br J Ophthalmol. 2012 Jul;96(7):935-40 Kriszt Á, Losonczy G, Berta A, Takács L.[eyerounds.org] Prominent corneal nerves: a novel sign of lipoid proteinosis. Br J Ophthalmol . 2012 Jul;96(7):935-40 Kriszt Á, Losonczy G, Berta A, Takács L.[webeye.ophth.uiowa.edu]

  • Hypopyon Ulcer

    Lagophthalmos, ectropion, trichiasis, conjunctival leproma, prominent corneal nerves, impaired corneal sensation, exposure keratitis, scleritis and chronic uveitis are commonly[bioline.org.br]

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