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800 Possible Causes for Prominent Nucleoli

  • Malignant Neoplasm

    nucleoli, lymph node metastases, and eventually overwhelming local recurrence and nodal metastases, resulting in death.[ncbi.nlm.nih.gov] Prominent nucleoli or irregular chomatin distribution within nuclei. Mitoses (especially irregular or bizarre mitoses).[library.med.utah.edu] […] bland appearance throughout the patient's entire clinical course, but did develop a pushing pattern of stromal invasion, increased mitotic activity, vesicular nuclei with prominent[ncbi.nlm.nih.gov]

  • BAP1-Related Tumor Predisposition Syndrome

    nucleoli and large, vesicular nuclei that vary substantially in size and shape.[mendelian.co] […] pedunculated, well-circumscribed papules with an average size of 5 mm, histologically predominantly composed of epithelioid melanocytes with abundant amphophilic cytoplasm, prominent[mendelian.co]

  • Primary Pigmented Nodular Adrenocortical Disease 1

    nucleoli and prominent lipofuscin deposits Also lipid-rich fasciculata-like cells May have focal necrosis, mitotic activity, trabecular growth pattern, myelolipomatous change[pathologyoutlines.com] Microscopically, the nodules consist of large cortical cells with eosinophilic cytoplasm and large hyperchromatic nuclei with prominent nucleoli.[academic.oup.com] Sharply circumscribed, but unencapsulated nodules composed of large eosinophilic lipid-poor cells similar to zona reticularis, but often with enlarged pleomorphic nuclei, prominent[pathologyoutlines.com]

  • Retroperitoneal Sarcoma

    They contained variable amounts of eosinophilic to vacuolated to amphophilic granular cytoplasms, and their nuclei were pleomorphic, containing prominent nucleoli and displaying[dx.doi.org] The nucleoli were pleomorphic and hyperchromatic with prominent nucleoli.[ispub.com] The nucleoli were pleomorphic and hyperchromatic with prominent nucleoli. Many branching vessels were seen throughout with bizarre multinucleate giant cells.[ispub.com]

  • Struma Ovarii

    nucleoli, hypercellularity, colloid scalloping, eosinophilic cytoplasm, mitoses, vascular invasion, cytologic atypia, nuclear pleomorphism, and cell size and type.[ncbi.nlm.nih.gov] […] biologically benign and malignant tumors: papillae, pseudo-papillae, psammoma bodies, nuclear grooves, nuclear overlap, "orphan Annie" nuclei, nuclear pseudo-inclusions, prominent[ncbi.nlm.nih.gov]

  • Tendon Sheath Giant Cell Tumor

    nucleoli • Oblong • Frequently blend with spindled forms • Variable numbers of giant cells • Similar type of nuclei • Usually contain 8-10 nuclei • Xanthoma cells • Sparse[tumorsurgery.org] nucleoli.[ijhas.in] nucleoli, and presence of atypical mitotic figures.[clinicalsarcomaresearch.biomedcentral.com]

  • Thyroid Lymphoma

    nucleoli Bizarre cells may be seen MALT lymphoma : Infiltration of thyroid epithelium creates lymphoepithelial lesions (lymphocytes "stuff" glandular lumina, Arch Pathol[pathologyoutlines.com] Figure 1: (a) Dyscohesive sheets of atypical cells having large vesicular nuclei and 1-3 prominent nucleoli.[ccij-online.org] FNAC from the right lobe showed monotonous population of intermediate to large lymphoid cells having prominent nucleoli, cleaved nuclei and moderate amount of cytoplasm in[cancerjournal.net]

  • Papillary Serous Cystadenocarcinoma of the Ovary

    nucleoli, stratification, frequent mitoses, stromal invasion (irregular or destructive infiltration by small glands or sheets of cells) Variable psammoma bodies (calcium[pathologyoutlines.com] The tumor cells were pleomorphic, with vesicular nucleus, prominent nucleoli and a moderate amount of eosinophilic cytoplasm.[ijpmonline.org] COMMENT: The morphology is compatible with a serous carcinoma (prominent nucleoli, large nuclear size variation, psammomatous calcifications).[librepathology.org]

  • Primary Malignant Melanoma of the Conjunctiva

    Tumor cells typically carry pleomorphic nuclei with irregular borders and prominent nucleoli.[symptoma.com] The tumor consisted of spindled and epithelioid cells with hyperchromatic nuclei, prominent nucleoli, and abundant cytoplasmic melanin pigment.[doctiktak.com]

  • Vaginal Sarcoma

    (b) The tumor cells comprised of spindle-shaped nuclei with blunt ends, coarse nuclear chromatin and prominent nucleoli.[ijabmr.org] The stromal cells have oval or round nuclei and prominent nucleoli surrounded by scant eosinophilic cytoplasm. They frequently have indistinct cell borders.[glowm.com] The tumor cells comprised of spindle-shaped nuclei with blunt ends, coarse nuclear chromatin and prominent nucleoli [Figure 1] b.[ijabmr.org]

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